Zobrazeno 1 - 10
of 362
pro vyhledávání: '"H L, Bonkovsky"'
Autor:
Hanh Nguyen, Suzanne U. Emerson, Kristina Faulk, H. L. Bonkovsky, Karly Mather, Udana Torian, Ronald E. Engle, E. Thompson
Publikováno v:
Journal of General Virology. 93:526-530
Hepatitis E virus is the aetiological agent of acute hepatitis E, a self-limiting disease prevalent in developing countries. Molecular analysis of viral genomic RNA from a chronically infected patient confirmed the recent discovery that chronic infec
Autor:
Suzuki A; Gastroenterology, Duke University, Durham, North Carolina, USA.; Gastroenterology, Durham VA Medical Center, Durham, North Carolina, USA., MinjunChen; Division of Bioinformatics and Biostatistics, FDA's National Center for Toxicological Research, Jefferson, Arkansas, USA.
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Nov 04. Date of Electronic Publication: 2024 Nov 04.
Publikováno v:
Journal of viral hepatitis. 18(10)
Chronic hepatitis C (CHC) infection caused by hepatitis C virus (HCV) is a major cause of liver disease and remains a major therapeutic challenge. A variety of host proteins interact with HCV proteins. The definitive role of cytoskeletal (CS) protein
Autor:
K K, Snow, H L, Bonkovsky, R J, Fontana, H-Y, Kim, R K, Sterling, A M, Di Bisceglie, T R, Morgan, J L, Dienstag, M G, Ghany
Publikováno v:
Alimentary pharmacologytherapeutics. 31(7)
Primary analysis of the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) Trial showed long-term peginterferon therapy did not reduce complications in patients with chronic hepatitis C and advanced fibrosis or cirrhosis.To assess t
Publikováno v:
Molecular and cellular biochemistry. 226(1-2)
Heme oxygenase-1, the major inducible isoform of heme oxygenase (HO), can be induced by heme and numerous other physical and chemical factors, many of which cause cellular 'stress'. This has led to the realization that HO-1 is a major highly conserve
Autor:
H L, Bonkovsky, D, Stefancyk, K, McNeal, B F, Banner, Q, Liu, G M, Zucker, J, Israel, J, Stagias, J, Colker
Publikováno v:
Digestive diseases and sciences. 46(10)
Compared to either drug alone, therapy with the combination of ribavirin and interferon-alpha leads to improved rates of response in patients with chronic hepatitis C. Side effects often mandate downward dose adjustment or cessation of therapy, and t
Publikováno v:
Molecular and cellular biochemistry. 209(1-2)
Previously, chick heme oxygenase-1 (cHO-1) gene was cloned by us and two regions important for induction by sodium arsenite were identified. These two regions were found to contain consensus sequences of an AP-1 (-1580 to -1573) and a MRE/cMyc comple
Autor:
R J, Fontana, J, Israel, P, LeClair, B F, Banner, K, Tortorelli, N, Grace, R A, Levine, G, Fiarman, M, Thiim, A S, Tavill, H L, Bonkovsky
Publikováno v:
Hepatology (Baltimore, Md.). 31(3)
Patients with chronic hepatitis C and low serum and hepatic iron stores may have an improved response to interferon (IFN). We tested whether iron reduction before and during IFN therapy would lead to an improved sustained biochemical and virological
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(3)
Patients with any of the acute porphyrias may suffer from acute attacks. If these patients are treated with certain drugs, such as barbiturates, the likelihood of developing an attack is increased. Patients treated with antidepressants or benzodiazep
Autor:
K K, Elbirt, H L, Bonkovsky
Publikováno v:
Proceedings of the Association of American Physicians. 111(5)
Heme oxygenase (HO) is responsible for the physiological breakdown of heme into equimolar amounts of biliverdin, carbon monoxide, and iron. Three isoforms (HO-1, HO-2, and HO-3) have been identified. HO-1 is ubiquitous and its mRNA and activity can b