Zobrazeno 1 - 10
of 164
pro vyhledávání: '"H Kogelberg"'
Autor:
R. Barbara Pedley, Kerry A. Chester, Richard H. J. Begent, Mark W. Lowdell, Tim Hillyer, Roland Contreras, Berend Tolner, Mathew Robson, H Kogelberg, Uzma Qureshi, Surinder K. Sharma, Wouter Vervecken
Publikováno v:
Glycobiology. 17:36-45
MFECP1 is a mannosylated antibody-enzyme fusion protein used in antibody-directed enzyme prodrug therapy (ADEPT). The antibody selectively targets tumor cells and the targeted enzyme converts a prodrug into a toxic drug. MFECP1 is obtained from expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2688722ad7bd42135a5bec709ff951
https://doi.org/10.1093/glycob/cwl053
https://doi.org/10.1093/glycob/cwl053
Publikováno v:
The Journal of Heart and Lung Transplantation. 34:S271-S272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989d8a3642bef6418d45adfcee32a2a7
https://doi.org/10.1016/j.healun.2015.01.759
https://doi.org/10.1016/j.healun.2015.01.759
Publikováno v:
The Journal of Heart and Lung Transplantation. 34:S150-S151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d09980c7f6102987c053188d463d5a36
https://doi.org/10.1016/j.healun.2015.01.405
https://doi.org/10.1016/j.healun.2015.01.405
Autor:
David W. Ellison, Berend Tolner, Stephen J. Mather, Carmen Picón, Enrique Miranda, Julie Foster, John Marshall, Gareth J. Thomas, Tim Meyer, Jerome Burnet, Kerry A. Chester, H Kogelberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e73260 (2013)
PLoS ONE, Vol 8, Iss 9, p e73260 (2013)
The αvβ6 integrin is up-regulated in cancer and wound healing but it is not generally expressed in healthy adult tissue. There is increasing evidence that it has a role in cancer progression and will be a useful target for antibody-directed cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c0f4ed9f9ac50bf66651f7dfa7d8c2
http://europepmc.org/articles/PMC3762766
http://europepmc.org/articles/PMC3762766
Publikováno v:
5th Biennial Conference on Heart Valve Biology and Tissue Engineering.
As immune responses likely contribute to degeneration of bioprosthetic heart valves (BHVs), this nonhuman primate study compares the anti-Gal antibody response to BHVs from wild type (WT) pigs (current BHVs) and those from α-galactosyltransferase kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85be8d9d7ed9945da97c3d92e2129cf2
https://doi.org/10.5339/qproc.2012.heartvalve.4.61
https://doi.org/10.5339/qproc.2012.heartvalve.4.61
Publikováno v:
The Journal of Heart and Lung Transplantation. 33:S167-S168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a98414758a0a9f7547867804e515c3c
https://doi.org/10.1016/j.healun.2014.01.450
https://doi.org/10.1016/j.healun.2014.01.450
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b54722fa998d08f006718990908bb9db
https://doi.org/10.1002/chin.199121273
https://doi.org/10.1002/chin.199121273
Autor:
Panagiotis G. Kyrtatos, Berend Tolner, Quentin A. Pankhurst, H Kogelberg, Kim Vigor, Khuloud T. Al-Jamal, Shane Minogue, Kerry A. Chester, Mark F. Lythgoe, Richard H. J. Begent, Kostas Kostarelos
Publikováno v:
Biomaterials. 31(6)
Superparamagnetic iron oxide nanoparticles (SPIONs) can substantially improve the sensitivity of magnetic resonance imaging (MRI). We propose that SPIONs could be used to target and image cancer cells if functionalised with recombinant single chain F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea0b956aa7f8acf98ef0bd31f30c65f
https://pubmed.ncbi.nlm.nih.gov/19889453
https://pubmed.ncbi.nlm.nih.gov/19889453
Autor:
Mark W. Lowdell, Ian R. Hart, Gareth J. Thomas, Berend Tolner, Daniel Marsh, Richard H. J. Begent, Bala Ramesh, Kerry A. Chester, Shane Minogue, H Kogelberg, Danielle Di Cara, Tim Meyer, John Marshall, Serena Sodha
The alpha v beta 6 integrin is a promising target for cancer therapy. Its expression is up-regulated de novo on many types of carcinoma where it may activate transforming growth factor-beta1 and transforming growth factor-beta 3, interact with the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022551d7e8f93d0bc54d33fd58ee229d
https://europepmc.org/articles/PMC2958364/
https://europepmc.org/articles/PMC2958364/
Autor:
Yie Chia Lee, Noelia Sainz-Pastor, Delin Zhu, Berend Tolner, Kerry A. Chester, Alexandra Huhalov, H Kogelberg, Richard H. J. Begent
Publikováno v:
International journal of biological macromolecules. 39(1-3)
Carcinoembryonic antigen (CEA) is a seven domain membrane glycoprotein widely used as a tumour marker for adenocarcinomas and as a target for antibody-directed therapies. Structural models have proposed that the first two domains of CEA (the N termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f569ea9daa502d1661c865ae7a436793
https://pubmed.ncbi.nlm.nih.gov/16678252
https://pubmed.ncbi.nlm.nih.gov/16678252