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Akademický článek

Rapid determination of apolipoprotein E phenotypes from whole plasma by automated isoelectric focusing using PhastSystem and immunofixation.

Autor: R Hackler, J R Schäfer, S Motzny, S Brand, T O Kleine, H Kaffarnik, A Steinmetz

Publikováno v: Journal of Lipid Research, Vol 35, Iss 1, Pp 153-158 (1994)

The influence of the genetic apolipoprotein (apo) E isoforms on human plasma lipoproteins is well established. There is, however, still a need for a phenotyping procedure applicable in laboratories not specialized in lipid research. To this end, we d

Externí odkaz: https://doaj.org/article/7c77ebf4ce6244a78bff75b242d6068f

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Akademický článek

Normolipemic dysbetalipoproteinemia and hyperlipoproteinemia type III in subjects homozygous for a rare genetic apolipoprotein E variant (apoE1).

Autor: A Steinmetz, N Assefbarkhi, C Eltze, K Ehlenz, H Funke, A Pies, G Assmann, H Kaffarnik

Publikováno v: Journal of Lipid Research, Vol 31, Iss 6, Pp 1005-1013 (1990)

A family with three heterozygote and two homozygote carriers of the rare apolipoprotein E1 isoform was detected by isoelectric focusing. One of the homozygous patients had type III hyperlipidemia, while the other showed normolipemic dysbetalipoprotei

Externí odkaz: https://doaj.org/article/6c47c6cbfce04444813dc4219f31f6c6

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Durch orale Kontrazeptiva induzierte Pankreatitis bei Hyperchylomikronämie-Syndrom

Autor: A. Steinmetz, Schaefer, K. Dugi, von Wichert P, K. Ehlenz, H. Kaffarnik

Publikováno v: DMW - Deutsche Medizinische Wochenschrift. 120:325-328

A now 24-year-old woman was found at the age of 2 years to have an hyperchylomicronaemia syndrome due to lipoprotein lipase deficiency: the triglyceride level was then 6000 mg/dl. But in subsequent years it had been reduced to between 550 and 2600 mg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02e39b5ee36a49f600f388f85effb86e
https://doi.org/10.1055/s-2008-1055349

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Adrenomyeloneuropathie: Eine häufige Ursache des Morbus Addison*

Autor: K. Ehlenz, C. Baerwald, Armin Steinmetz, H. Kaffarnik, C. Pilz, J. R. Schafer, P. von Wichert, D. H. Hunneman

Publikováno v: DMW - Deutsche Medizinische Wochenschrift. 119:327-331

Adrenomyeloneuropathy (AMN) is a "milder form" of adrenoleukodystrophy with a X-linked inheritance. Abnormal catabolism of the very long-chain fatty acids (VLCFA) results in Addison's disease and spastic paraparesis. The VLCFA concentration was measu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::328c939eb2ea52e34b93e946a1e33ba0
https://doi.org/10.1055/s-2008-1058698

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Metabolic basis of high density lipoproteins and apolipoprotein A-I increase by HMG-CoA reductase inhibition in healthy subjects and a patient with coronary artery disease

Autor: Bernhard Maisch, H. Kaffarnik, H.J. Seyberth, Armin Steinmetz, Horst Schweer, J. R. Schaefer, Katsunori Ikewaki, H. Stracke

Publikováno v: Atherosclerosis. 144:177-184

HMG-CoA reductase inhibitors, such as pravastatin, are widely used as lipid lowering drugs in hypercholesterolemia. Pravastatin does not only reduce the atherogenic low density lipoprotein (LDL)-cholesterol, but is also increasing high density lipopr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7124956607ef40409943893d64741074
https://doi.org/10.1016/s0021-9150(99)00053-2

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Multicenter Comparison of Micronized Fenofibrate and Simvastatin in Patients with Primary Type IIA or IIB Hyperlipoproteinemia

Autor: Uwe Hehnke, Thomas Schwartz, H. Kaffarnik, Armin Steinmetz

Publikováno v: Journal of Cardiovascular Pharmacology. 27:563-570

In 12 weeks of active treatment, we compared the efficacy and safety of a new (micronized) formulation of fenofibrate (F) (200 mg/day) with that of simvastatin (S) (20 mg/day), an inhibitor of hydroxy-methyl-glutaryl coenzyme A (HMG-CoA)-reductase. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec59dbc6c6adf96ff8dbc7806c965f1
https://doi.org/10.1097/00005344-199604000-00016

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The Influence of Apolipoprotein E Polymorphism on Plasma Concentrations of Apolipoprotein B and A-I During the First Year of Life

Autor: W, Herrmann, S, Hanf, H, Kaffarnik, S, Motzny, J, Reissner, A, Steinmetz

Publikováno v: Pediatrics. 93:296-302

Apolipoprotein (apo)E polymorphism has been shown to be associated with different serum levels of cholesterol, apoB, and apoE. In clarifying the degree of influence of the apoE isoforms, investigations in an early stage of life are useful. The aim of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f9e779628ff20b8f479e76c3fa1c8d
https://doi.org/10.1542/peds.93.2.296

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