Zobrazeno 1 - 10
of 190
pro vyhledávání: '"H K Spencer"'
Autor:
T. P. Jerussi, L. V. Kudzma, H. K. Spencer, N. L. Lalinde, J. A. Colapret, M. J. Benvenga, J. R. Bagley, B.‐S. Huang, Theodore C. Spaulding, M. H. Ossipov, B. M. Doorley, B.‐S. Lin
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b52466b5347d8c0ac12bc1bf7c5b9ffd
https://doi.org/10.1002/chin.199149339
https://doi.org/10.1002/chin.199149339
Autor:
J. R. Bagley, Theodore C. Spaulding, B. M. Doorley, S A Thomas, Michael H. Ossipov, Frieda G. Rudo, H. K. Spencer, Mark J. Benvenga, T. P. Jerussi
Publikováno v:
Journal of Medicinal Chemistry. 34:827-841
A series of new 1-(heterocyclyalkyl)-4-(propionanilido)-4-piperidinyl methyl esters and methylene methyl ethers have been synthesized and pharmacologically evaluated. In the mouse hot-plate test, the majority of compounds exhibited an analgesia (ED50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b2488784bafa855e397dd63e2b3563
https://doi.org/10.1021/jm00106a051
https://doi.org/10.1021/jm00106a051
Autor:
van der Wiel, Erik1 (AUTHOR) e.vanderwiel@uu.nl, Thieulot, Cedric1 (AUTHOR), van Hinsbergen, Douwe J. J.1 (AUTHOR)
Publikováno v:
Solid Earth. 2024, Vol. 15 Issue 7, p861-875. 15p.
Publikováno v:
Journal of medicinal chemistry. 33(10)
The synthesis and intravenous analgesic activity of a series of 3-methyl-4-(N-phenyl amido)piperidines, entries 34-79, is described. The methoxyacetamide pharmacophore produced a series of compounds with optimal analgesic potency and short duration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bf85374972f0bfee284a332a5940512
https://pubmed.ncbi.nlm.nih.gov/2170652
https://pubmed.ncbi.nlm.nih.gov/2170652
Autor:
E. F. Ezell, M. H. Ossipov, Frieda G. Rudo, L. V. Kudzma, M. J. Benvenga, V. V. Knight, Theodore C. Spaulding, S. A. Severnak, H. K. Spencer
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4cc49f5aafa98626298d5edb768206
https://doi.org/10.1002/chin.199017183
https://doi.org/10.1002/chin.199017183
Autor:
C. M. Dee, Arthur E. Schwartz, Noeleen Ostapkovich, H K Spencer, R. S. Matteo, J G Stone, Eugene Ornstein
Publikováno v:
Anesthesiology. 75:A1065-A1065
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f80a6610f76ac2a43ccc1843da92d326
https://doi.org/10.1097/00000542-199109001-01064
https://doi.org/10.1097/00000542-199109001-01064
Autor:
B. M. Doorley, J. R. Bagley, Frieda G. Rudo, H. K. Spencer, Theodore C. Spaulding, R. L. Wynn
Publikováno v:
Journal of Medicinal Chemistry. 32:663-671
A research program based on certain heterocyclic modifications (12-50) of the fentanyl (1) molecule has generated a novel class of opioids. In the mouse hot-plate test, these compounds were weaker analgesics than 1. Two types of antagonists were obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9dfa6e13dd177be45ef1443d649851
https://doi.org/10.1021/jm00123a028
https://doi.org/10.1021/jm00123a028
Autor:
Malhan, Deeksha1 (AUTHOR), Schoenrock, Britt2 (AUTHOR), Yalçin, Müge1,3,4 (AUTHOR), Blottner, Dieter2,5 (AUTHOR), Relόgio, Angela1,3,4 (AUTHOR) angela.relogio@medicalschool‐hamburg.de
Publikováno v:
Aging Cell. Sep2023, Vol. 22 Issue 9, p1-23. 23p.
Autor:
Taghizadeh, M. J.1 (AUTHOR) mohammadjavadtaghizadeh31@yahoo.com, Hosseini, S. J.1 (AUTHOR), Moosavi, S. M.1 (AUTHOR), Parsa, H.1 (AUTHOR)
Publikováno v:
Journal of Heterocyclic Chemistry. Jun2023, Vol. 60 Issue 6, p950-956. 7p.
Autor:
Taimisto, Marjaana1 (AUTHOR), Poropudas, Merja J.1 (AUTHOR), Rautiainen, J. Mikko2 (AUTHOR), Oilunkaniemi, Raija1 (AUTHOR) raija.oilunkaniemi@oulu.fi, Laitinen, Risto S.1 (AUTHOR) risto.laitinen@oulu.fi
Publikováno v:
European Journal of Inorganic Chemistry. 5/12/2023, Vol. 26 Issue 14, p1-7. 7p.