Zobrazeno 1 - 10
of 37
pro vyhledávání: '"H K Blomhoff"'
Autor:
Kirsten Skarstad, Harald B. Steen, L. Smedshammer, H. K. Blomhoff, T. S. Jonassen, Trond Stokke
Publikováno v:
Cell Proliferation. 30:197-218
The protein kinase inhibitor staurosporine (SSP) was employed to study the involvement of kinases in human cell cycle progression. Thirty to 100 ng/ml SSP blocks entry into S phase and M phase. Lack of entry into S phase is due to impaired activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3163e95f87e0fcf50680fdb67fa71183
https://doi.org/10.1046/j.1365-2184.1997.00087.x
https://doi.org/10.1046/j.1365-2184.1997.00087.x
Publikováno v:
Blood. 87:1728-1736
Previous studies have shown that retinoic acid (RA), similar to tumor necrosis factor-alpha (TNF-alpha), can act as a bifunctional regulator of the growth of bone marrow progenitors, in that it can stimulate granulocyte-macrophage colony-stimulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf52bfad3272d4965526f3245eafeb1
https://doi.org/10.1182/blood.v87.5.1728.1728
https://doi.org/10.1182/blood.v87.5.1728.1728
Publikováno v:
The Journal of Immunology. 155:58-65
In the present paper we demonstrate that physiologic levels (10 nM) of both all-trans- and 9-cis-retinoic acid (RA) are potent inhibitors of the growth of human as well as murine B cell precursors in vitro. Ten nanomolar concentrations of all-trans-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ea5b7ffc08f17d15f8f05020852228
https://doi.org/10.4049/jimmunol.155.1.58
https://doi.org/10.4049/jimmunol.155.1.58
Publikováno v:
The Journal of Immunology. 154:1634-1643
TGF-beta and agents that elevate intracellular cAMP levels are potent inhibitors of B cell activation in vitro and have been shown to arrest stimulated B cells in the G1 phase of the cell cycle. We tested the effects of TGF-beta 1 and the cAMP-induci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f51fdfbbfdac59d3188009a989c69a07
https://doi.org/10.4049/jimmunol.154.4.1634
https://doi.org/10.4049/jimmunol.154.4.1634
Publikováno v:
The Journal of Immunology. 153:4997-5007
The CD53 pan-leukocyte glycoprotein is a member of the recently described tetraspan family of cell membrane proteins. The structure and functional characteristics of these molecules indicate that they may play important roles in transmembrane signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb10f19103c1b2e986f1b58adf8e777
https://doi.org/10.4049/jimmunol.153.11.4997
https://doi.org/10.4049/jimmunol.153.11.4997
Autor:
Anne Aas‐Eng, Catharina de Lange Davies, H. K. Blomhoff, Bjørn K. Erikstein, Klaus Beiske, Erlend B. Smeland, Steinar Funderud
Publikováno v:
European Journal of Immunology. 22:1149-1155
Within the hematopoietic system, CDw75 is primarily expressed on cells of the B cell lineage. Cloning and sequencing of the gene has shown CDw75 to be a beta-galactoside alpha-2,6-sialyltransferase. This enzyme plays an important role in the intracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7f120a69cfb4b877f0c0ebca5ebeb7
https://doi.org/10.1002/eji.1830220507
https://doi.org/10.1002/eji.1830220507
Publikováno v:
European journal of immunology. 30(6)
cAMP is an important physiological mediator of lymphoid growth inhibition. The purpose of the present study was to establish the link between cAMP and the cell cycle machinery leading to inhibition of G1/S transition in human peripheral blood lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35d1a22e321ac18627341a99ee12ea58
https://pubmed.ncbi.nlm.nih.gov/10898514
https://pubmed.ncbi.nlm.nih.gov/10898514
Autor:
S, Naderi, H K, Blomhoff
Publikováno v:
Blood. 94(4)
The mechanisms underlying the growth-inhibitory effect of retinoids on normal human B lymphocytes are not well understood. We addressed this issue by examining the effect of retinoic acid on the cell cycle machinery involved in G1/S transition. When
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fad6eeb734ed6aeb4080f129e0ca8a1
https://pubmed.ncbi.nlm.nih.gov/10438723
https://pubmed.ncbi.nlm.nih.gov/10438723
Publikováno v:
Journal of cellular physiology. 180(1)
During B- and T-cell ontogeny, extensive apoptosis occurs at distinct stages of development. Agents that increase intracellular levels of cAMP induce apoptosis in thymocytes and mature B cells, prompting us to investigate the role of cAMP signaling i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab2d42d14f44b49a8b52267658ba1e5e
https://pubmed.ncbi.nlm.nih.gov/10362019
https://pubmed.ncbi.nlm.nih.gov/10362019
Autor:
S, Naderi, H K, Blomhoff
Publikováno v:
Journal of cellular physiology. 178(1)
The protein Mad1 heterodimerizes with Max to form an E-box binding complex able to interfere with the transcriptional and transforming activities of c-Myc. Downregulation of c-Myc accompanied by induction of Mad1 upon differentiation has fueled the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b464ebfe4e68badbfa16b27742a9d8c
https://pubmed.ncbi.nlm.nih.gov/9886493
https://pubmed.ncbi.nlm.nih.gov/9886493