Zobrazeno 1 - 10
of 21
pro vyhledávání: '"H K, Manji"'
Autor:
W Z Potter, H K Manji
Publikováno v:
Clinical Chemistry. 40:279-287
Despite extensive research, the biochemical abnormalities underlying the predisposition to and the pathogenesis of affective disorders remain to be clearly established. Efforts to study norepinephrine (NE) output and function have utilized biochemica
Autor:
H K, Manji, R S, Duman
Publikováno v:
Psychopharmacology bulletin. 35(2)
Mood disorders have traditionally been conceptualized as neurochemical disorders, but there is now evidence from a variety of sources demonstrating regional reductions in central nervous system (CNS) volume, as well as reductions in the numbers and/o
Publikováno v:
The International Journal of Neuropsychopharmacology. 4
Publikováno v:
The British journal of psychiatry : the journal of mental science. 178(Suppl 41)
Background New research is dramatically altering our understanding of the molecular mechanisms underlying neuronal communication. Aim To elucidate the molecular mechanisms underlying the therapeutic effects of mood stabilisers. Method Results from in
Publikováno v:
Bipolar disorders. 2(3 Pt 2)
It has become increasingly appreciated that the long-term treatment of complex neuropsychiatric disorders like bipolar disorder (BD) involves the strategic regulation of signaling pathways and gene expression in critical neuronal circuits. Accumulati
Autor:
H K, Manji, R H, Lenox
Publikováno v:
The Journal of clinical psychiatry.
The underlying pathophysiology of bipolar disorder is a continually evolving complexity of multilayer interacting and independent systems. The dearth of adequate preclinical or clinical models that incorporate the various features of the illness, i.e
Publikováno v:
The Journal of clinical psychiatry. 61
Although mood disorders have traditionally been conceptualized as "neurochemical disorders," considerable literature from a variety of sources demonstrates significant reductions in regional central nervous system (CNS) volume and cell numbers (both
Autor:
H K, Manji, R H, Lenox
Publikováno v:
Biological psychiatry. 46(10)
Understanding the biology of the pharmacological stabilization of mood will undoubtedly serve to provide significant insight into the pathophysiology of manic-depressive illness (MDI). Accumulating evidence from our laboratories and those of other re
Publikováno v:
The Journal of clinical psychiatry. 60
In an attempt to find the key to reducing the excessive morbidity and mortality seen with mood disorders, our laboratory has been extensively investigating lithium's mechanisms of action in an integrated series of clinical and preclinical studies. We
Autor:
H K, Manji, R H, Lenox
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 19(3)