Zobrazeno 1 - 10
of 11
pro vyhledávání: '"H J de Aizpurua"'
Publikováno v:
Proceedings of the National Academy of Sciences. 89:9841-9845
Insulin-dependent diabetes mellitus (IDDM) is associated with serum antibodies that precipitate a 64-kDa pancreatic islet cell protein reported to be glutamic acid decarboxylase (GAD; glutamate decarboxylase, EC 4.1.1.15). Previously, antibodies to G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8779093d2c9d23d213d67fa13ea6b0b
https://doi.org/10.1073/pnas.89.20.9841
https://doi.org/10.1073/pnas.89.20.9841
Autor:
Iain L. Campbell, Leonard C. Harrison, Thomas Loudovaris, Jonathan Cebon, Peter G. Colman, Brian D. Tait, H J De Aizpurua
Publikováno v:
Diabetes. 40:1128-1133
A simple, direct assay for T-lymphocyte reactivity to islet antigen(s) in human insulin-dependent diabetes mellitus (IDDM) should facilitate preclinical diagnosis and the evaluation of intervention therapy to avert autoimmune-mediated β-cell destruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55aeb52892dd05f905e4f34779a094e9
https://doi.org/10.2337/diab.40.9.1128
https://doi.org/10.2337/diab.40.9.1128
Publikováno v:
The Journal of physiology. 465
1. Rat phaeochromocytoma (PC12) cells were used to investigate the expression of Ca2+ channel types during neuronal differentiation. Neuronal differentiation was induced by treatment with nerve growth factor (NGF) or by activation of a temperature-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364f3008a68646568892d42c6815a057
https://pubmed.ncbi.nlm.nih.gov/8229838
https://pubmed.ncbi.nlm.nih.gov/8229838
Publikováno v:
The Journal of Experimental Medicine
Oral immunization of an animal is generally hard to achieve unless large quantities of antigen are administered. In this study a number of antigens were tested for their ability to elicit a systemic immune response upon oral administration. It was fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02598880d972c9821df152227031d50
https://doi.org/10.1084/jem.167.2.440
https://doi.org/10.1084/jem.167.2.440
Publikováno v:
Clinical and experimental immunology. 62(3)
Sera from 20 of 24 patients with pernicious anaemia reacted by immunoblotting with a 65-70 kD protein in canine and rodent gastric mucosal cells enriched for 80-90% parietal cells, and in microsomal preparations derived from these cells. All 20 react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84c5768cf3da3f8c676ba901558f3158
https://pubmed.ncbi.nlm.nih.gov/4085153
https://pubmed.ncbi.nlm.nih.gov/4085153
Publikováno v:
The New England journal of medicine. 313(8)
We examined serum IgG fractions from 20 patients with pernicious anemia and 25 control subjects for their capacity to inhibit binding of [125I]15-leu human gastrin-17 to parietal-cell-enriched gastric mucosal cells. IgG fractions from six patients re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3d5506433d7570aae0780ed9995dc4
https://pubmed.ncbi.nlm.nih.gov/2991762
https://pubmed.ncbi.nlm.nih.gov/2991762
Publikováno v:
Clinical and experimental immunology. 61(2)
We examined 51 sera from patients with pernicious anaemia for their capacity to block maximal gastrin stimulation of acid secretion by isolated rodent gastric parietal cells. 14C-aminopyrine accumulation was used as the index of acid secretion in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24185304f2ae65c7f6d530fc76218bd1
https://pubmed.ncbi.nlm.nih.gov/4042425
https://pubmed.ncbi.nlm.nih.gov/4042425
Publikováno v:
Clinical and experimental immunology. 54(2)
Using flow microfluorimetry (FMF), 60 sera from patients with pernicious anaemia (PA) were examined for immunoreactivity with the surface membranes of viable canine parietal cells. FMF analyses showed that the percentage of parietal cells giving a su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::639bfd01e34ed066992801fee7366acb
https://pubmed.ncbi.nlm.nih.gov/6652965
https://pubmed.ncbi.nlm.nih.gov/6652965
Publikováno v:
Cancer research. 48(17)
The Lambert-Eaton myasthenic syndrome (LES) is an autoimmune presynaptic disorder of peripheral cholinergic neurotransmission in which there is often an associated small cell lung carcinoma (SCC). SCC lines established from patients with and without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1a13ea1fdd92777a38baee6503b6634
https://pubmed.ncbi.nlm.nih.gov/2457429
https://pubmed.ncbi.nlm.nih.gov/2457429
Autor:
J R, Underwood, F T, Mu, F, Alderuccio, W, Williams, H J, De Aizpurua, J S, Pedersen, P J, Chalmers, B H, Toh
Publikováno v:
Journal of clinicallaboratory immunology. 17(3)
A monoclonal IgMk antibody secreted by a hybrid (MUI-6) of mouse plasmacytoma NS-1 with spleen cells from a mouse immunized with canine parietal cell-enriched gastric mucosal cells was tested for immunofluorescence reactivity with gastric mucosal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60f506f7fe0d16ec559df82b2772d53d
https://pubmed.ncbi.nlm.nih.gov/3900410
https://pubmed.ncbi.nlm.nih.gov/3900410