Zobrazeno 1 - 8
of 8
pro vyhledávání: '"H J Brentzel"'
Autor:
G F Tutwiler, H J Brentzel
Publikováno v:
Biochemical Pharmacology. 29:1421-1427
Pirogliride, a new orally active hypoglycemic agent, was shown to be an effective inhibitor of renal and hepatic gluconeogenesis in isolated rat kidney cortex slices, hepatocytes and perfused liver. The inhibition was concentration dependent (0.1–1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469e7fb97025d6012486d993843d65ce
https://doi.org/10.1016/0006-2952(80)90438-4
https://doi.org/10.1016/0006-2952(80)90438-4
Autor:
H. J. Brentzel, Ronald G. Thurman
Publikováno v:
Alcoholism, clinical and experimental research. 1(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f7e427898f5964c1c1900f55d843a0
https://pubmed.ncbi.nlm.nih.gov/201176
https://pubmed.ncbi.nlm.nih.gov/201176
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 178(2)
The oral hypoglycemic agent, methyl 2-tetradecylglycidate (Me-TDGA), which inhibits in vitro mitochondrial carnitine palmitoyl transferase A (CPT-A) was used to study the relationship of CPT inhibition to changes in ketonemia and glycemia in normal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e555fc2eb030424bd5de72a6aa568cc
https://pubmed.ncbi.nlm.nih.gov/3969383
https://pubmed.ncbi.nlm.nih.gov/3969383
Publikováno v:
Federation proceedings. 34(11)
Rat liver microsomes oxidized ethanol two to three times faster than propanol when incubated with either an NADPH- or an H2O2-generating system. In addition, solubilized, purified microsomal subfractions were found to contain protein with an electrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2981b3de3e3fd10221d3a4f709107963
https://pubmed.ncbi.nlm.nih.gov/240743
https://pubmed.ncbi.nlm.nih.gov/240743
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489951830
Perfused livers from ethanol pretreated rats utilized ethanol and acetaldehyde at higher rates than appropriate controls. This adaptive increase in hepatic ethanol and acetaldehyde uptake was associated with a marked (greater than 60%) increase in he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9984ea04d3b8919fcbd46fee70c7832d
https://doi.org/10.1007/978-1-4899-5181-6_16
https://doi.org/10.1007/978-1-4899-5181-6_16
Publikováno v:
Advances in experimental medicine and biology.
Perfused livers from ethanol pretreated rats utilized ethanol and acetaldehyde at higher rates than appropriate controls. This adaptive increase in hepatic ethanol and acetaldehyde uptake was associated with a marked (greater than 60%) increase in he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01e060c514412f845b7a42f08f213a11
https://pubmed.ncbi.nlm.nih.gov/562603
https://pubmed.ncbi.nlm.nih.gov/562603
Uptake of acetaldehyde in the perfused liver was linear at acetaldehyde concentrations between 0.08 and l. O mM. The intramitochondrial pyridine nucleotide redox state increased as a function of the rate of acetaldehyde uptake. Fructose stimulated ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a263cd4eb0cea1506cd8938884c2ea0d
https://doi.org/10.1016/b978-0-12-691403-0.50033-1
https://doi.org/10.1016/b978-0-12-691403-0.50033-1
Autor:
C L, Arteaga, T D, Brown, J G, Kuhn, H S, Shen, T J, O'Rourke, K, Beougher, H J, Brentzel, D D, Von Hoff, G R, Weiss
Publikováno v:
Cancer research. 49(16)
Brequinar sodium is a 4-quinolinecarboxylic acid analogue that inhibits dihydroorotate dehydrogenase and subsequent de novo pyrimidine biosynthesis. It has shown dose-dependent antineoplastic activity against several mouse and human tumor models. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4082178dc521abd8598ac80340b817fb
https://pubmed.ncbi.nlm.nih.gov/2743343
https://pubmed.ncbi.nlm.nih.gov/2743343