Zobrazeno 1 - 10
of 242
pro vyhledávání: '"H J, Mest"'
Publikováno v:
Annals of the New York Academy of Sciences. 763:620-633
Moxonidine is a centrally acting antihypertensive agent with potent action on I1-imidazoline receptors. Moxonidine as an SIR modulator elicits a persistent reduction in circulating levels of epinephrine, demonstrating a reduction in sympathetic tone.
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 50:115-121
Different HDL preparations from rabbit blood were injected intravenously (10 mg HDL protein/injection and animal) into cholesterol fed rabbits twice a week for 8 weeks. The composition of the used high density lipoprotein (HDL) was modified by dietar
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 46:197-201
Vasopressor response and release of eicosanoids following intravenous injection of arachidonic acid (AA) were examined in normotensive rats. AA administration caused a rapid initial fall of arterial pressure followed by a brief rise and a subsequent
Publikováno v:
Prostaglandins. 43:331-338
The influence of a transient asphyxia on cochlear potentials, i.e. endolymphatic potential (EP), summating potential (SP) and cochlear microphonics (CM) was investigated in guinea pigs when pretreating the animals with various substances interacting
Autor:
J. Beitz, H.-J. Mest
Publikováno v:
Cardiovascular Drug Reviews. 9:385-397
Publikováno v:
Klinische Monatsblätter für Augenheilkunde. 199:278-282
BN 52 021, a specific antagonist of PAF receptors, was tested in the early-phase treatment of chemically burned eyes in 30 rabbits. The local application of BN 52 021 eyedrops-1% (water-soluble preparation, 5 times daily, in comparison with the other
Publikováno v:
European Journal of Ophthalmology. 1:137-141
S 872419 A, a specific receptor antagonist of peptide leukotrienes, was tested in the early-phase treatment of chemically burned eye (0.25 mol/l sodium hydroxide) of the rabbit. The drug was topically applied 5 times a day in a 1% solution, controls
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 40:211-215
The i.v. administration of high density lipoprotein (HDL) into cholesterol fed rabbits decreased statistically significantly the serum level of total cholesterol and of low density lipoprotein cholesterol after a feeding period of 8 weeks. These dimi
Publikováno v:
Drug Development Research. 19:321-327
Trapidil and some other 5,7-disubstituted s-triazolo(1,5-a) pyrimidine derivatives (TD's: AR 12455, AR 12456, AR 12463, AR 12465), which have been shown to possess inhibitory effects on proliferative activity in cultured cells, influenced the cyclic
Autor:
H.-J. Mest, Rolf Mentlein
Publikováno v:
Diabetologia. 48(4)
Inhibitors of the regulatory protease dipeptidyl peptidase-IV (DPP-IV) are currently under development in preclinical and clinical studies (several pharmaceutical companies, now in Phase III) as potential drugs for the treatment of type 2 diabetes. T