Zobrazeno 1 - 10
of 34
pro vyhledávání: '"H J, Lewis"'
Autor:
James M. Seckler, Paulina M. Getsy, Walter J. May, Benjamin Gaston, Santhosh M. Baby, Tristan H. J. Lewis, James N. Bates, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
We have provided indirect pharmacological evidence that hypoxia may trigger release of the S-nitrosothiol, S-nitroso-L-cysteine (L-CSNO), from primary carotid body glomus cells (PGCs) of rats that then activates chemosensory afferents of the carotid
Externí odkaz:
https://doaj.org/article/a0ec66bd442e4023aed4041f3f036733
Autor:
Tristan H. J. Lewis, Junqi Zhuo, Jacob X. McClellan, Paulina M. Getsy, Rita M. Ryan, Michael. J. Jenkins, Stephen J. Lewis
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The left and right occipital arteries provide blood supply to afferent cell bodies in the ipsilateral nodose and petrosal ganglia. This supply is free of an effective blood-ganglion barrier, so changes in occipital artery blood flow directly affect t
Externí odkaz:
https://doaj.org/article/4e9e29bb50784b01a82ffda00a8445d2
Autor:
Paulina M. Getsy, Santhosh M. Baby, Walter J. May, James N. Bates, Christopher R. Ellis, Michael G. Feasel, Christopher G. Wilson, Tristan H. J. Lewis, Benjamin Gaston, Yee-Hsee Hsieh, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
We are developing a series of thiolesters that produce an immediate and sustained reversal of the deleterious effects of opioids, such as morphine and fentanyl, on ventilation without diminishing the antinociceptive effects of these opioids. We repor
Externí odkaz:
https://doaj.org/article/58575678264d4a8ca9cc27c71351a745
Autor:
Paulina M. Getsy, Santhosh M. Baby, Walter J. May, Alex P. Young, Benjamin Gaston, Matthew R. Hodges, Hubert V. Forster, James N. Bates, Christopher G. Wilson, Tristan H. J. Lewis, Yee-Hee Hsieh, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cell-penetrant thiol esters including the disulfides, D-cystine diethyl ester and D-cystine dimethyl ester, and the monosulfide, L-glutathione ethyl ester, prevent and/or reverse the deleterious effects of opioids, such as morphine and fentanyl, on b
Externí odkaz:
https://doaj.org/article/498c8bb8e48f4686a17a66cbccf872fb
Autor:
Paulina M. Getsy, Santhosh M. Baby, Ryan B. Gruber, Benjamin Gaston, Tristan H. J. Lewis, Alan Grossfield, James M. Seckler, Yee-Hsee Hsieh, James N. Bates, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Endogenous and exogenously administered S-nitrosothiols modulate the activities of central and peripheral systems that control breathing. We have unpublished data showing that the deleterious effects of morphine on arterial blood-gas chemistry (i.e.,
Externí odkaz:
https://doaj.org/article/917a88664b534ff3bbaeda91c4bb6f4b
Publikováno v:
Journal of Applied Physiology. 134:1188-1206
We present data showing that the ventilatory responses elicited by a hypoxic gas challenge in male C57BL6 mice are markedly altered by coexposure to hypercapnic gas challenge with hypercapnic responses often dominating the hypoxic responses. These da
Autor:
M. McGuire, H. J. Lewis
Publikováno v:
Proceeding of Flexible Automation and Integrated Manufacturing 1998.
Publikováno v:
Psychology in the Schools. 59:471-479
Autor:
Tristan H J, Lewis, Walter J, May, Alex P, Young, James N, Bates, Santhosh M, Baby, Paulina M, Getsy, Rita M, Ryan, Yee-Hsee, Hsieh, James M, Seckler, Stephen J, Lewis
Publikováno v:
Biomedicine & Pharmacotherapy. 156:113939
This study demonstrates that intravenous infusion of the cell-penetrant thiol ester, L-cysteine ethyl ester (L-CYSee), to adult male Sprague-Dawley rats elicited (a) minor alterations in frequency of breathing, expiratory time, tidal volume, minute v
Autor:
F. M. Coughlan, H. J. Lewis
Publikováno v:
Journal of Adhesion Science and Technology. 22:801-813
Electrically conductive adhesives (ECAs) have been utilised in the internal bonding of leads to chips for some time. With the need to replace leaded solder, ECAs are an obvious candidate as a drop-in replacement. This paper discusses the general make