Zobrazeno 1 - 10
of 22
pro vyhledávání: '"H J, Kool"'
Publikováno v:
Mutation research. 473(1)
Loss of heterozygosity (LOH) of tumour suppressor genes is a crucial step in the development of sporadic and hereditary cancer. Recently, we and others have developed mouse models in which the frequency and nature of LOH events at an autosomal locus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca269a002e600b2a7b081dbbf4cee4c4
https://pubmed.ncbi.nlm.nih.gov/11166024
https://pubmed.ncbi.nlm.nih.gov/11166024
Autor:
S W, Wijnhoven, H J, Kool, C T, van Oostrom, R B, Beems, L H, Mullenders, A A, van Zeeland, G T, van der Horst, H, Vrieling, H, van Steeg
Publikováno v:
Cancer research. 60(20)
Cockayne syndrome (CS) patients are deficient in the transcription coupled repair (TCR) subpathway of nucleotide excision repair (NER) but in contrast to xeroderma pigmentosum patients, who have a defect in the global genome repair subpathway of NER,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::760dc98f5592366eb5f3a96f6dd75683
https://pubmed.ncbi.nlm.nih.gov/11059760
https://pubmed.ncbi.nlm.nih.gov/11059760
Publikováno v:
C R C Critical Reviews in Environmental Control. 12:307-357
The following subjects in the review article will be considered: (1) The presence or organic compounds in drinking water in relation to possible health effects; (2) Epidemiological studies on the health effects of water borne diseases caused by organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a6275ce21456334e95bba844d9bc124
https://doi.org/10.1080/10643388209381699
https://doi.org/10.1080/10643388209381699
Publikováno v:
Science of The Total Environment. 15:137-147
Several water samples of the rivers Rhine and Meuse have been tested for mutagenic activity in the Ames Salmonella/microsome assay and a fluctuation assay. Samples were taken at places where the rivers enter The Netherlands and at several downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ef835848805ac08ce79fe83b3ec15e
https://doi.org/10.1016/0048-9697(80)90004-2
https://doi.org/10.1016/0048-9697(80)90004-2
Publikováno v:
Toxicological & Environmental Chemistry. 7:111-129
An inventory on the presence of mutagenic activity (Ames test) in 18 cities (20 drinking water types) was carried out in The Netherlands. Fourteen drinking water types of twenty showed mutagenic activity in the Ames test in volumes varying from 0.5 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a765929c6056f90ed189ed7db52a4767
https://doi.org/10.1080/02772248409357021
https://doi.org/10.1080/02772248409357021
Publikováno v:
Environmental Health Perspectives
A retrospective epidemiological study in The Netherlands showed a statistical association between chlorination by-products in drinking water and cancer of the esophagus and stomach for males. A pilot-plant study with alternative disinfectants was car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4c7e1a743907ef3b0f1564711980f6
https://doi.org/10.1289/ehp.8246197
https://doi.org/10.1289/ehp.8246197
Publikováno v:
Chemosphere. 10:85-98
A study of the effects of different XAD-resins, bed volume, flow rate, pH and type of eluent on the extraction of organic mutagens from surface water is presented. XAD-4/8 is as effective as XAD-2 in concentrating organic mutagens from surface water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b10a955df1e033094df6ecff10dca4
https://doi.org/10.1016/0045-6535(81)90172-7
https://doi.org/10.1016/0045-6535(81)90172-7
Autor:
J. Hrubec, H. J. Kool
Publikováno v:
Ozone: Science & Engineering. 8:217-234
Three disinfectants, viz. chlorine, chlorine dioxide, and ozone, were compared with respect to the formation of organic mutagens and halogenated organic compounds in drinking water. Chlorine increased the mutagenic activity (Ames test) drastically, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1c656ddfcc293a023537d12bb8df9f2
https://doi.org/10.1080/01919518608552404
https://doi.org/10.1080/01919518608552404
Publikováno v:
Science of The Total Environment. 47:229-256
Treatment processes which are applied in The Netherlands during the preparation of drinking water have been evaluated with regard to introduction and removal of organic mutagens as well as halogenated organics. It appeared that the most efficient pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bd2bf5774ac4b801775ea8984eac7a
https://doi.org/10.1016/0048-9697(85)90333-x
https://doi.org/10.1016/0048-9697(85)90333-x