Zobrazeno 1 - 10
of 135
pro vyhledávání: '"H J, Klimisch"'
Publikováno v:
Human & Experimental Toxicology. 24:95-99
Wistar rats were exposed to 2-methoxypropylacetate-1 (2-MPAc-1) vapours in concentrations of 0, 110, 560 and 2800 ppm for (equiv. to 0; 0.6; 3.0 and 14.9 mg/L) for 4 weeks in chambers (6 hours/day; 5 days/week; five male and five female animals per g
Publikováno v:
Toxicology Letters. 105:231-237
To assess the prenatal toxicity to rats of the anti-foaming agent, tri-isobutylphosphate (CAS 126-71-6), a study was conducted in which daily dosages of 0, 100, 300 and 1000 mg/kg were administered to different treatment groups by gavage from day 6 t
Publikováno v:
Food and Chemical Toxicology. 36:165-168
A 90-day subchronic inhalation toxicity study was performed on Wistar rats in accordance to OECD testing guidelines to evaluate the toxicological profile of 2-ethylhexanol, potential target organs, and a no-observable-adverse-effect-level (NOAEL). 10
Publikováno v:
Human & Experimental Toxicology. 16:722-726
1 90-day subchronic toxicity studies with 3-methyl-1- butanol (MEB) and 2-methyl-1-propanol (MEP) were performed on rats to evaluate the toxicological profile of the compounds under conditions of drinking water studies, to identify the potential targ
Publikováno v:
Food and Chemical Toxicology. 35:1061-1074
N-Vinylpyrrolidone-2 (NVP) is a monomeric compound used as an industrial intermediate. Nine of 11 studies previously reported involved exposure of rats (two different strains), mice or hamsters to NVP by the inhalation route at concentrations of up t
Publikováno v:
Fundamental and Applied Toxicology. 38:143-147
This study was carried out to provide information on the effects of inhalation of diethylene glycol monoethyl ether, a substance used in industry which may be accidentally inhaled by man. Sprague-Dawley CD rats were exposed by inhalation to a test at
Publikováno v:
Inhalation Toxicology. 9:623-646
Aerosolized n -butyl acetate (n -BA) was reported to have an LC50 value of approximately 160 ppm in a study conducted by 3M at NOTOX. Six follow-up studies at three laboratories (BASF, BRRC, NOTOX) were conducted in an attempt to reproduce this value
Publikováno v:
Toxicological Sciences. 38:143-147
This study was carried out to provide information on the effects of inhalation of diethylene glycol monoethyl ether, a substance used in industry which may be accidentally inhaled by man. Sprague–Dawley CD rats were exposed by inhalation to a test
Autor:
B. Broecker, Helmut Greim, H.-J. Klimisch, R. Vogel, H. Hollander, H.-P. Gelbke, K. Ziegler-Skylakakis, G. Stropp, J. Ahlers, N. Schön, I. Mangelsdorf, E. Bayer, A. Paetz, C. Weber, R. Bias
Publikováno v:
Chemosphere. 28:2203-2236
Currently available data on toxicological and ecotoxicological endpoints for sulfonic acids have been compiled by the BUA. This compilation reveals a common toxicological profile for the sulfonic acids when all the properties of these substances are
Autor:
G. Welter, B. Broecker, R. Bias, W.G. Haltrich, J. Ahlers, H.-J. Klimisch, R. Vogel, H.-P. Gelbke, I. Mangelsdorf, A.O. Gamer, E. Bayer, N. Schön, G. Stropp, Helmut Greim
Publikováno v:
Chemosphere. 26:1653-1666
A method is described, which allows a rapid classification of chemicals. Based on data sets, exposure and ecotoxic and toxic effects are evaluated to enable overall classification into the following groups: I) Chemicals probably hazardous for man or