Zobrazeno 1 - 10
of 14
pro vyhledávání: '"H J, Federoff"'
Autor:
K A, Maguire-Zeiss, H J, Federoff
Publikováno v:
Ernst Schering Research Foundation workshop. (53)
The convergent pathobiologic model of Parkinson's disease stipulates that disparate insults initiate a disease process that obligately share a common pathway leading to cell death. A combinatorial treatment which targets various steps in this pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ff36e97fff65aff3001ce1100bb1974
https://pubmed.ncbi.nlm.nih.gov/16315613
https://pubmed.ncbi.nlm.nih.gov/16315613
Autor:
H J, Federoff
Publikováno v:
Ernst Schering Research Foundation workshop. (43)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1e70438498e2bec175a70acdb2da395
https://pubmed.ncbi.nlm.nih.gov/12894455
https://pubmed.ncbi.nlm.nih.gov/12894455
Autor:
M. W. Halterman, H. J. Federoff
Publikováno v:
CNS Neuroprotection ISBN: 9783642076251
Ischemia in the central nervous system produces a heterogeneous pattern of neuronal loss, which is dependent on the extent, duration, and distribution of vessel occlusion. Profound hypoperfusion produces neuronal necrosis in a matter of hour, resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::531820db1e2a1225413ce49cf3f10a2f
https://doi.org/10.1007/978-3-662-06274-6_12
https://doi.org/10.1007/978-3-662-06274-6_12
Publikováno v:
Current opinion in molecular therapeutics. 3(5)
The efficient and targeted transfer of genes is the goal of gene therapy. In the central nervous system (CNS), this is challenging due in part to the exquisite anatomy of the brain. Herpes simplex virus (HSV) vectors are particularly amenable to CNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::596e8b9c1d2839a4a969a2d9d7557d7d
https://pubmed.ncbi.nlm.nih.gov/11699893
https://pubmed.ncbi.nlm.nih.gov/11699893
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(10)
Evidence for the presence of a novel transporter in primary cultures of rat striatal neurons and mouse cortical neurons similar in function to the multidrug resistance-associated protein (MRP1) is presented. Functional activity was assessed by efflux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3fe514947a1b0ebca03f37ec9218d73
https://pubmed.ncbi.nlm.nih.gov/11560867
https://pubmed.ncbi.nlm.nih.gov/11560867
Autor:
H J, Federoff, M, Atkinson
Publikováno v:
Progress in brain research. 117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e68431e61c97e545f6832ffd173c72f4
https://pubmed.ncbi.nlm.nih.gov/9932428
https://pubmed.ncbi.nlm.nih.gov/9932428
Autor:
R. H. An, C.‐S. Liang, Jing Xia, E. Dong, A. Brooks, H. J. Federoff, B. M. Heath, Robert S. Kass
Publikováno v:
The Journal of physiology. 512
1. The electrophysiological and pharmacological properties of cardiac myocytes from the hearts of adult transgenic mice engineered to overexpress nerve growth factor (NGF) in the heart were studied. 2. There was a 12% increase in the ventricular myoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6cbdc7f5dde62cf84eda7db3eae7f0
https://pubmed.ncbi.nlm.nih.gov/9769421
https://pubmed.ncbi.nlm.nih.gov/9769421
Publikováno v:
Hepatology (Baltimore, Md.). 22(3)
Retroviral vectors have been widely studied as vehicles for hepatocyte gene therapy, but they are limited by an inability to infect nondividing cells and the need for prolonged cell culture. Two replication deficient herpes simplex viral vectors (HSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eba0f269747519ff75de387e8fad78e4
https://pubmed.ncbi.nlm.nih.gov/7657275
https://pubmed.ncbi.nlm.nih.gov/7657275
Publikováno v:
Molecular medicine (Cambridge, Mass.). 1(5)
BACKGROUND: Chronic diabetes causes structural changes in the retinal capillaries of nearly all patients with a disease duration of more than 15 years. Acellular occluded vessels cause hypoxia, which stimulates sight-threatening abnormal angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87e37507655996ce5dcbb3a1a4a74b01
https://pubmed.ncbi.nlm.nih.gov/8529118
https://pubmed.ncbi.nlm.nih.gov/8529118
Autor:
H J Federoff
Publikováno v:
Gene Therapy. 10:365-366
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84c7f148b9712e5f9da13b834b1ac72
https://doi.org/10.1038/sj.gt.3301964
https://doi.org/10.1038/sj.gt.3301964