Zobrazeno 1 - 10
of 13
pro vyhledávání: '"H J, Clewell"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: ß-chloroprene (2-chloro-1,3-butadiene; CP) causes lung tumors after inhalation exposures in rats and mice. Mice develop these tumors at lower exposures than rats. In rats CP exposures cause depletion of lung glutathione (GSH).Methods:
Externí odkaz:
https://doaj.org/article/58999fb3e0744a04b0c9dfbee0d38f0e
Autor:
H J, Clewell, J L, Campbell, C, Van Landingham, A, Franzen, M, Yoon, D E, Dodd, M E, Andersen, P R, Gentry
Publikováno v:
Inhalation toxicology. 32(9-10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0bdb26afc61164958cbf0aba39f0151c
https://pubmed.ncbi.nlm.nih.gov/32791864
https://pubmed.ncbi.nlm.nih.gov/32791864
Autor:
N. P. Page, D. V. Singh, W. Farland, J. I. Goodman, R. B. Conolly, M. E. Andersen, H. J. Clewell, C. B. Frederick, H. Yamasaki, G. Lucier
Publikováno v:
Toxicological Sciences. 37:16-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b83075f7f6265bd64aaa7d2df200e7
https://doi.org/10.1093/toxsci/37.1.16
https://doi.org/10.1093/toxsci/37.1.16
Publikováno v:
Toxicological Sciences. 21:258-269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eeadf61227e1728e767f4c49f502c95
https://doi.org/10.1093/toxsci/21.3.258
https://doi.org/10.1093/toxsci/21.3.258
Publikováno v:
Environmental Health Perspectives
A physiologically based pharmacokinetic (PBPK) model was developed that provides a comprehensive description of the kinetics of trichloroethylene (TCE) and its metabolites, trichloroethanol (TCOH), trichloroacetic acid (TCA), and dichloroacetic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbe531373fa5ecd96c68ac0320da641
https://pubmed.ncbi.nlm.nih.gov/10807559
https://pubmed.ncbi.nlm.nih.gov/10807559
Autor:
Hugh A. Barton, rd H J Clewell
Publikováno v:
Environmental Health Perspectives
Alternatives for developing chronic exposure limits for noncancer effects of trichloroethylene (TCE) were evaluated. These alternatives were organized within a framework for dose-response assessment--exposure:dosimetry (pharmacokinetics):mode of acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2973681db35e8b4a6cbc69abfec870c7
https://pubmed.ncbi.nlm.nih.gov/10807562
https://pubmed.ncbi.nlm.nih.gov/10807562
Autor:
H J, Clewell, J M, Gearhart, P R, Gentry, T R, Covington, C B, VanLandingham, K S, Crump, A M, Shipp
Publikováno v:
Risk analysis : an official publication of the Society for Risk Analysis. 19(4)
An analysis of the uncertainty in guidelines for the ingestion of methylmercury (MeHg) due to human pharmacokinetic variability was conducted using a physiologically based pharmacokinetic (PBPK) model that describes MeHg kinetics in the pregnant huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3820347ddbe34c9bfbcafa517c0a3d53
https://pubmed.ncbi.nlm.nih.gov/10765421
https://pubmed.ncbi.nlm.nih.gov/10765421
Publikováno v:
Mercury as a Global Pollutant ISBN: 9789401040693
An analysis was performed of a large epidemiological study conducted in New Zealand to evaluate the neurological effects of prenatal methylmercury (MeHg) exposure in children. In the epidemiological study, 6-year-old children, whose mothers had been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::380aa2a983240722153e42a36ba4c0eb
https://doi.org/10.1007/978-94-011-0153-0_6
https://doi.org/10.1007/978-94-011-0153-0_6
Publikováno v:
Risk analysis : an official publication of the Society for Risk Analysis. 14(4)
The parameters in a physiologically based pharmacokinetic (PBPK) model of methylene chloride were varied systematically, and the resulting variation in a number of model outputs was determined as a function of time for mice and humans at several expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cd108b320f254e6ac05c1983b8ed92
https://pubmed.ncbi.nlm.nih.gov/7972956
https://pubmed.ncbi.nlm.nih.gov/7972956
Publikováno v:
Journal of pharmaceutical sciences. 83(5)
The kinetics of water vapor absorption-desorption was studied in the porcine stratum corneum (sc) at 25 degrees C. Dry sc samples were exposed to several relative humidities followed by exposure to dry air, and the change in weight was monitored over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b09fd869908ff398afbe865b55f6126
https://pubmed.ncbi.nlm.nih.gov/8071823
https://pubmed.ncbi.nlm.nih.gov/8071823