Zobrazeno 1 - 10
of 75
pro vyhledávání: '"H Hoge"'
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nucleosome profiling from cell-free DNA (cfDNA) represents a potential approach for cancer detection and classification. Here, the authors develop Griffin, a computational framework for tumour subtype classification based on cfDNA nucleosome profilin
Externí odkaz:
https://doaj.org/article/a2aa19ff06af40648abe298b2dc9bb6b
Autor:
Anna C. H. Hoge, Michal Getz, Anat Zimmer, Minjeong Ko, Linoy Raz, Rameen Beroukhim, Todd R. Golub, Gavin Ha, Uri Ben David
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-7 (2022)
Abstract Genomic evolution of patient-derived xenografts (PDXs) may lead to their gradual divergence away of their tumors of origin. We previously reported the genomic evolution of the copy number (CN) landscapes of PDXs during their engraftment and
Externí odkaz:
https://doaj.org/article/0ee932769b144f99adb5cd6d33e0312c
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0c649e0ae1ad4fdc955cfa5df22bd466
Autor:
Anna C. H. Hoge, Michal Getz, Anat Zimmer, Minjeong Ko, Linoy Raz, Rameen Beroukhim, Todd R. Golub, Gavin Ha, Uri Ben-David
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/86d55386cbab4b8db646e0b027a9e238
Autor:
C. Kikawa, Peter S. Nelson, Jonathan Reichel, Joseph B. Hiatt, Gavin Ha, M. Ko, Anna C. H. Hoge, Zachary Weber, K. Santos, H. Liao, K. Chen, Paz Polak, R. D. Patton, Heather A. Parsons, A. E. Cruikshank, David MacPherson, Anna-Lisa Doebley, N. De Sarkar, Viktor A. Adalsteinsson, M. Adil, Daniel G. Stover
Cell-free DNA (cfDNA) has the potential to inform tumor subtype classification and help guide clinical precision oncology. Here we developed Griffin, a new method for profiling nucleosome protection and accessibility from cfDNA to study the phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::185396b2c9af9216f56097d088cb65d1
https://doi.org/10.1101/2021.08.31.21262867
https://doi.org/10.1101/2021.08.31.21262867
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature communications. 13(1)
Cell-free DNA (cfDNA) has the potential to inform tumor subtype classification and help guide clinical precision oncology. Here we develop Griffin, a framework for profiling nucleosome protection and accessibility from cfDNA to study the phenotype of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5562d4a0e2e6705d4023073d2fe1691f
https://pubmed.ncbi.nlm.nih.gov/36463275
https://pubmed.ncbi.nlm.nih.gov/36463275
Autor:
Susan E. Erdman, Sushmita Patwardhan, Sean M. Gibbons, Anna C. H. Hoge, Sean M. Kearney, Robert L. Moritz, Ulrike Kusebauch, Christian Diener
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Broad spectrum antibiotics cause both transient and lasting damage to the ecology of the gut microbiome. Antibiotic-induced loss of gut bacterial diversity has been linked to susceptibility to enteric infections. Prior work on subtherapeutic antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52a9587db754138a6577348c047c80f
https://doi.org/10.1038/s42003-021-01841-8
https://doi.org/10.1038/s42003-021-01841-8
Autor:
Gavin Ha, Roman Gulati, Jonathan Reichel, Pankaj Vats, Andrew J. Armstrong, Colin C. Pritchard, Arul M. Chinnaiyan, Vaibhav G. Patel, Rana R. McKay, Anna C. H. Hoge, Ajjai Alva, William Oh, R. Bruce Montgomery, Deepak Kilari, Landon C. Brown, Michael T. Schweizer, Tanya B. Dorff
Publikováno v:
JCO Precis Oncol
PURPOSE Translational studies have shown that CDK12 mutations may delineate an immunoresponsive subgroup of prostate cancer, characterized by high neo-antigen burden. Given that these mutations may define a clinically distinct subgroup, we sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5753fd80165dc1328ffe28ce5f2d4a
https://europepmc.org/articles/PMC7363399/
https://europepmc.org/articles/PMC7363399/
Autor:
Paz Polak, Gavin Ha, Anna-Lisa Doebley, Heather A. Parsons, Caroline Kikawa, Viktor A. Adalsteinsson, Eden Cruikshank, Minjeong Ko, Joseph B. Hiatt, Peter S. Nelson, Daniel G. Stover, David MacPherson, Anna C. H. Hoge, Navonil De Sarkar, Hanna Liao
Publikováno v:
Cancer Research. 81:LB022-LB022
Background: Cell-free DNA (cfDNA) is released from dying cells, including tumor cells, and can be isolated from peripheral blood for studying cancer. In the bloodstream, cfDNA is protected from degradation by nucleosomes and other DNA binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::557358cec3d0eb07205cd65bbdb94e49
https://doi.org/10.1158/1538-7445.am2021-lb022
https://doi.org/10.1158/1538-7445.am2021-lb022
Autor:
R H, HOGE, A M, SALZBERG
Publikováno v:
The Southern surgeon. 16(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c42b807db3a818e6c45e580bf740b08
https://pubmed.ncbi.nlm.nih.gov/24538260
https://pubmed.ncbi.nlm.nih.gov/24538260