Zobrazeno 1 - 10
of 59
pro vyhledávání: '"H H, Wellhöner"'
Autor:
H. J. Kalz, H. H. Wellhöner
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 353:606-609
The influence of cytosol acidification on the uptake of two-chain tetanus toxin (TeTX)1 by neurohybridoma cells NG 108-15 and NBr-l0A was investigated with two established techniques, the NH4C1 pulse method and the pH-clamp method. With the former, t
Autor:
H. H. Wellhöner
Publikováno v:
Selective Neurotoxicity ISBN: 9783540578154
Tetanus toxin and the botulinum toxins A, B, Cl, D, E, F, and G are proteins produced by bacilli of the genus Clostridium. The eight toxins have a similar structure, they are translocated into neurons by adsorptive endocytosis, and they act predomina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acda2ce2292ec6cd75082c52ff6c4bfc
https://doi.org/10.1007/978-3-642-85117-9_11
https://doi.org/10.1007/978-3-642-85117-9_11
Publikováno v:
The Journal of biological chemistry. 266(7)
The transferrin cycle was used to attempt the import of bioactive macromolecules into cells with the aid of an acid-labile cross-linking agent. Anti-tetanus F(ab')2 fragments were iodinated and then conjugated to transferrin with a newly developed ac
Autor:
H.-H. Wellhöner
Publikováno v:
Delir und Delirprophylaxe in der Intensivmedizin ISBN: 9783798508804
Ein korpulenter Landtagsabgeordneter von 45 Jahren erleidet wahrend einer Fahrt auf der Autobahn einen Koronarinfarkt und wird zur nachstgelegenen Intensivstation transportiert. Zwei und funf Stunden spater gerat er in eine Kammertachykardie und wird
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00f374dfba0a042e4de0d94078b61f56
https://doi.org/10.1007/978-3-642-85416-3_2
https://doi.org/10.1007/978-3-642-85416-3_2
Autor:
H H, Wellhöner, H, Bigalke, T, Borcholte, G, Erdmann, T, Eschenhagen, K H, Jung, P, Marxen, U, Peukert, D M, Neville, K, Srinivasachar
Publikováno v:
Journal de physiologie. 84(3)
1. In order to introduce antitetanus immunoglobulin fragments into eukaryotic cells, either antitetanus F(ab')2 or Fab' fragments have been linked to carrier molecules. Aciclovir, horseradish peroxidase, wheat germ agglutinin, and transferrin were tr
Publikováno v:
AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie. 17:207-210
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 307:287-290
1. The effect of tetanus toxin injected into one gastrocnemius muscle on the steady state concentration of several amino acids was investigated in spinal cord half segments, spinal roots and dorsal root ganglia of rats. Care was taken to ensure a sym
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 290:357-373
The distribution of radioactivity in the sciatic nerve, the spinal ganglia, the ventral roots and the spinal cord was studied by means of histoautoradiography after injection of 125I-labelled tetanus toxin into gastrocnemius muscles of cats. In the s
Autor:
H H Wellhöner, D M Neville
Publikováno v:
Journal of Biological Chemistry. 262:17374-17378
Differentiated neuroblastoma x glioma hybrid cells NG 108-15 express on their surface specific binding sites for tetanus toxin. 450 sites/cell with a KD of 2 x 10(-11) M were found under "physiological" conditions of pH and salt concentrations. A Hil
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 323:50-62
1. The effect of veratridine on the electrical properties of giant neurones in the sub-oesophageal ganglion of the snail Helix pomatia has been investigated. 2. Veratridine (10−5 g/ml) caused a depolarization of 14–30 mV. Some of the cells showed