Zobrazeno 1 - 10
of 69
pro vyhledávání: '"H H, Sussman"'
Autor:
J L, Twiss, H G, Wada, K S, Fok, S D, Chan, A N, Verity, G T, Baxter, E M, Shooter, H H, Sussman
Publikováno v:
Journal of neuroscience research. 51(4)
The role of the low affinity neurotrophin receptor p75LNTR in neurotrophin signal transduction remains open. Recent reports show that this receptor generates intracellular signals independent of Trk activity, and others imply that it collaborates wit
Publikováno v:
Cell motility and the cytoskeleton. 35(1)
Microtubules play an essential role in cell division. Little is known about possible variations of total tubulin and tubulin isotype expression during the cell cycle. We analyzed the total tubulin content, tubulin polymerization status and tubulin is
Publikováno v:
Journal of Biological Chemistry. 254:12629-12635
Evidence is presented demonstrating the existence of a receptor specific for transferrin on the brush border membrane of the human syncytial trophoblast. Equilibrium-binding studies were conducted using a placental vesicle preparation to demonstrate
Publikováno v:
Clinical Chemistry. 32:381-385
Automated digoxin immunoassays with the Abbott TDx, Dade Stratus, and Du Pont aca were evaluated against an RIA similar to the Centers for Disease Control Candidate Reference Method. All three automated methods correlated poorly with the reference me
Publikováno v:
Journal of Biological Chemistry. 259:2689-2692
Treatment of K562 cells with the iron chelator desferrioxamine results in the gradual increase in total cell receptors for transferrin. Receptor number rises 2.5-4.5-fold over 24 h and remains at the elevated level if the chelator is continuously pre
Autor:
B S Stein, H H Sussman
Publikováno v:
Journal of Biological Chemistry. 258:2668-2673
Human transferrin receptor protein from various human cell lines in tissue culture (phytohemagglutinin-activated lymphocytes, normal embryonic fibroblasts (WI-38), a choriocarcinoma (Be Wo), an epidermoid carcinoma (KB), and a metastatic breast carci
Autor:
H H Sussman, H Tsunoo
Publikováno v:
Journal of Biological Chemistry. 258:4118-4122
The effect of endogenous ligand on transferrin binding to receptor was investigated using a Triton X-100 extract of acetone powder from human placentae as the source of transferrin receptor. This extract contained 2.0 +/- 0.4 micrograms of endogenous
Autor:
H H Sussman, M A Ludueña
Publikováno v:
Journal of Biological Chemistry. 251:2620-2628
The alkaline phosphatase from KB cells was purified, characterized, and compared to placental alkaline phosphatase, which it resembles immunologically. Two nonidentical nonomeric subunits of the KB phosphatase were found. The two subunits, which have
Publikováno v:
Journal of Biological Chemistry. 259:14762-14772
Monensin blocks human transferrin recycling in a dose-dependent and reversible manner in K562 cells, reaching 100% inhibition at a noncytocidal dose of 10(-5) M, whereas transferrin recycling is virtually unaffected by noncytocidal doses of chloroqui
Autor:
H H Sussman, B S Stein
Publikováno v:
Journal of Biological Chemistry. 261:10319-10331
The endocytosis and recycling of the human transferrin receptor were evaluated by several experimental modalities in K562 cells perturbed with 10(-5) M monensin. The work presented is an extension of a previous study demonstrating both complete inhib