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of 1 277
pro vyhledávání: '"H Gutierrez"'
Autor:
Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
In silico immunogenicity risk assessment has been an important step in the development path for many biologic therapeutics, including monoclonal antibodies. Even if the source of a given biologic is ‘fully human’, T cell epitopes that are contain
Externí odkaz:
https://doaj.org/article/d3ac97f35912434aae9b77e2b10534c0
Autor:
Naonobu Sugiyama, Frances E. Terry, Andres H. Gutierrez, Toshitaka Hirano, Masato Hoshi, Yasushi Mizuno, William Martin, Shin’ichiro Yasunaga, Hiroaki Niiro, Keishi Fujio, Anne S. De Groot
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
HypothesisWhile conventional in silico immunogenicity risk assessments focus on measuring immunogenicity based on the potential of therapeutic proteins to be processed and presented by a global population-wide set of human leukocyte antigen (HLA) all
Externí odkaz:
https://doaj.org/article/d63f2dd7b89147808053eb17c4804104
Autor:
Diana S. Vargas-Bermudez, Alixs Constanza Gil-Silva, María F. Naranjo-Ortíz, José Darío Mogollón, Jair F. Gómez-Betancur, José F. Estrada, Álvaro Aldaz, Harold Garzón-González, José Angulo, Dennis Foss, Andres H. Gutierrez, Jairo Jaime
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1119 (2024)
Porcine circovirus type 2 (PCV2) is strongly linked to a group of syndromes referred to as porcine-circovirus-associated diseases (PCVADs), which are controlled through vaccination; however, this does not induce sterilizing immunity but is instead in
Externí odkaz:
https://doaj.org/article/38fc7cd937b544369b498ffd1ad732d6
Autor:
Arantza Lamas-Paz, Mariana Mesquita, Marcos Garcia-Lacarte, Olga Estévez-Vázquez, Raquel Benedé-Ubieto, Alejandro H. Gutierrez, Hanghang Wu, Hector Leal Lasalle, Javier Vaquero, Rafael Bañares, Eduardo Martínez-Naves, Sergio Roa, Yulia A. Nevzorova, Gonzalo Jorquera, Francisco Javier Cubero
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundAlcohol misuse, binge drinking pattern, and gender-specific effects in the middle-aged population has been clearly underestimated. In the present study, we focused on understanding gender-specific effects of alcohol exposure on the gut-live
Externí odkaz:
https://doaj.org/article/04f399f45ea04962a6213b1a6c44fd11
Publikováno v:
Exploration of Digestive Diseases, Vol 2, Iss 3, Pp 83-99 (2023)
The pathogenesis of drug-induced liver injury (DILI) is still in an early stage of research. However, investigators have shown that both oxidative stress and endoplasmic reticulum (ER) stress play a significant role in the pathological mechanism. How
Externí odkaz:
https://doaj.org/article/bc422d69d6424680beb943efca7e4a22
Autor:
S. M. Shahjahan Miah, Sandra Lelias, Andres H. Gutierrez, Mitchell McAllister, Christine M. Boyle, Lenny Moise, Anne S. De Groot
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pathogens escape host defenses by T-cell epitope mutation or deletion (immune escape) and by simulating the appearance of human T cell epitopes (immune camouflage). We identified a highly conserved, human-like T cell epitope in non-structural protein
Externí odkaz:
https://doaj.org/article/b15d41c0df4c413b9ef411ccc4ae045f
Autor:
José A. Fernández-Gutiérrez, Oscar A. Reyes-Cisneros, Mark R. Litzow, Lorena Bojalil-Álvarez, Elizabeth García-Villaseñor, Eliezer Tomas Gómez-Gomez, Iván Murrieta-Álvarez, David Gomez-Almaguer, Cesar H. Gutierrez-Aguirre, Amado J. Karduss-Urueta, Guillermo J. Ruiz-Delgado, Guillermo José Ruiz-Argüelles
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 449-455 (2022)
Introduction High-dose melphalan (HD-Mel) has been successfully employed in autografting patients with multiple myeloma. An advantage of this regimen is that the total dose of Mel can be delivered in a single day, being particularly useful when non-f
Externí odkaz:
https://doaj.org/article/fa4ee3b7bae5467c86d85eb20a31901d
Akademický článek
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Akademický článek
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Autor:
Mohini A. Gunnett, Elizabeth Baker, Cathy Mims, Staci T. Self, Hector H. Gutierrez, Jennifer S. Guimbellot
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundSome infants undergoing newborn screening (NBS) tests have inconclusive sweat chloride test (SCT) results that lead to the designation of Cystic Fibrosis Screen Positive, Inconclusive Diagnosis/CFTR-related metabolic syndrome (CFSPID/CRMS).
Externí odkaz:
https://doaj.org/article/8035a43de04d4eb3973b919031e6fc56