Výsledky vyhledávání

Subchronic Vapor Inhalation Toxicity Studies on 3.1 Oil in Male Fischer 344 Rats

Autor: David R. Mattie, Carlyle D. Flemming, H. F. Leahy, H. G. Wall, E.R. Kinkead, R. E. Whitmire, E. C. Kimmel

Publikováno v: Inhalation Toxicology. 3:357-377

3.1 Oil is a chlorofluorocarbon oil consisting of C6 and C8 oligomers of chlorotriflu-oroethylene. Physical properties such as high thermal stability, good lubricity, and high dielectric strength make 3.1 oil promising for potential use in hydraulic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d62f2d0d3539b9e70ebe0bd7c81f5352
https://doi.org/10.3109/08958379109145295

Zobrazit plný text záznamu

The Effects of Exercise Following Exposure to Bis(Trefluoromethyl) Disulfide

Autor: D. H. Moore, H. G. Wall

Publikováno v: Drug and Chemical Toxicology. 14:343-352

Bis(trifluoromethyl) disulfide (TFD) was originally designed for use as an agricultural fumigant. Inhalation of toxic doses of TFD results in varying degrees of pulmonary edema. The purpose of this study was to determine if exhaustive exercise would

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6923d9f1313d0f8e3a8a9910a65823
https://doi.org/10.3109/01480549109011638

Zobrazit plný text záznamu

Comparative Hepatotoxicity of Two Polychlorotrifluoroethylenes (3.1 Oils) and Two Chlorotrifluoroethylene (CTFE) Oligomers in Male Fischer 344 Rats

Autor: N. J. DELRASO, C. S. GODIN, C. E. JONES, H. G. WALL, D. R. MATTIE, C. D. FLEMMING

Publikováno v: Toxicological Sciences. 17:550-562

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ec2bc30392e8c3a6d0bdab50ab5d7a7
https://doi.org/10.1093/toxsci/17.3.550

Zobrazit plný text záznamu

Safety of omeprazole paste in foals and mature horses

Autor: H. G. Wall, C. P. Daurio, J. L. Cox, D. H. Wallace, D. K. Attebery, R. E. Plue

Publikováno v: Equine veterinary journal. Supplement. (29)

Omeprazole has been shown to promote healing of spontaneously occurring gastric ulcers in horses when administered for 28 days at a dose of 4 mg/kg bwt/day and to prevent recurrence of ulcers in almost all horses when treatment is continued at a dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b79d63dd983d020c2fed87b059d581d
https://pubmed.ncbi.nlm.nih.gov/10696297

Zobrazit plný text záznamu

Evaluation of the promotion potential of chlorotrifluoroethylene trimer acid in male Sprague-Dawley rats

Autor: C D Flemming, H G Wall, J M Drerup, C S Godin

Publikováno v: Toxicology letters. 66(1)

The promoting effect of chlorotrifluoroethylene trimer acid (TRA), a metabolite of the 6-carbon oligomer of Halocarbon 3.1 oil, was investigated using a bioassay designed to detect enzyme-altered foci. These oligomers, as well as their carboxylic aci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534be25e785ebc134a054c0d32b0216b
https://pubmed.ncbi.nlm.nih.gov/8093986

Zobrazit plný text záznamu

The toxicologic and oncogenic potential of JP-4 jet fuel vapors in rats and mice: 12-month intermittent inhalation exposures

Autor: Carlyle D. Flemming, D. R. Mattie, Richard H. Bruner, T. P. O'neill, H. G. Wall, E.R. Kinkead, C. A. Russell

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 20(1)

Three-hundred Fischer 344 rats and 300 C57BL/6 mice of each sex were divided into three treatment groups and exposed intermittently (6 hr/day, 5 days/week) to JP-4 jet fuel vapors at concentrations of 0, 1000, and 5000 mg/m3 for 12 months. At exposur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c500b5306807a1f958bcb762a8793b3
https://pubmed.ncbi.nlm.nih.gov/8432432

Zobrazit plný text záznamu

Comparative hepatotoxicity of two polychlorotrifluoroethylenes (3.1 oils) and two chlorotrifluoroethylene (CTFE) oligomers in male Fischer 344 rats

Autor: N J, DelRaso, C S, Godin, C E, Jones, H G, Wall, D R, Mattie, C D, Flemming

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 17(3)

Polychlorotrifluoroethylene (3.1 oil) is a nonflammable hydraulic fluid composed of chlorotrifluoroethylene (CTFE) oligomers of different carbon chain lengths (C5 to C9), primarily six (trimer) and eight (tetramer) carbons. Four test groups of Fische

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e677390b193056e1e5b4607debd15e0
https://pubmed.ncbi.nlm.nih.gov/1794657

Zobrazit plný text záznamu

Chloropentafluorobenzene: short-term inhalation toxicity, genotoxicity and physiologically-based pharmacokinetic model development

Autor: E R, Kinkead, H G, Wall, C J, Hixson, R R, Tice, R S, Kutzman, A, Vinegar

Publikováno v: Toxicology and industrial health. 6(6)

Ten Fischer 344 rats and six B6C3F1 mice of each sex were exposed to air, 0.25, 0.80, or 2.50 mg chloropentafluorobenzene (CPFB)/liter of air for three weeks, excluding weekends. Exposure to 2.50 mg/liter caused a reduction in the growth rate of rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dfc957f218e413cde0660de5e18ffae
https://pubmed.ncbi.nlm.nih.gov/2097818

Zobrazit plný text záznamu

Development of an Initiation/Promotion Assay to Detect Foci of Enzyme-Altered Hepatocytes

Autor: H. G. Wall, C. S. Godin

The progression of biochemical and morphological changes that occur following the transformation of a normal cell to a malignant cell have been poorly understood. There have been nine well-documented experimental protocols that have been developed an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cabf2b53d76461072d3c7121ab5a867
https://doi.org/10.21236/ada221927

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání