Zobrazeno 1 - 10
of 30
pro vyhledávání: '"H F, Yam"'
Autor:
Andri K. Riau, Zhuojian Look, Gary H. F. Yam, Craig Boote, Qian Ma, Evelina J. Y. Han, Nur Zahirah binte M. Yusoff, Hon Shing Ong, Tze-Wei Goh, Nuur Shahinda Humaira binte Halim, Jodhbir S. Mehta
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Intrastromal cell therapy utilizing quiescent corneal stromal keratocytes (qCSKs) from human donor corneas emerges as a promising treatment for corneal opacities, aiming to overcome limitations of traditional surgeries by reducing procedural
Externí odkaz:
https://doaj.org/article/4ceb77a7600e4c138995de9678ab67d4
Autor:
Beau J. Fenner, Nur Zahirah B. M. Yusoff, Matthias Fuest, Lei Zhou, Francisco Bandeira, Howard Y. Cajucom-Uy, H. K. Tan, Jodhbir S. Mehta, Gary H. F. Yam
Publikováno v:
Eye and Vision, Vol 6, Iss 1, Pp 1-14 (2019)
Abstract Background Human corneal stromal keratocytes propagated in culture media supplemented with human amnion extract (AME) can correct early corneal haze in an animal model. Clinical application of cultivated keratocytes is limited by infectious
Externí odkaz:
https://doaj.org/article/75738034ce6e4282a6acf44db0839e08
Autor:
Nur Zahirah binte M. Yusoff, Andri K. Riau, Gary H. F. Yam, Nuur Shahinda Humaira binte Halim, Jodhbir S. Mehta
Publikováno v:
Cells, Vol 11, Iss 1, p 178 (2022)
The human corneal stroma contains corneal stromal keratocytes (CSKs) that synthesize and deposit collagens and keratan sulfate proteoglycans into the stromal matrix to maintain the corneal structural integrity and transparency. In adult corneas, CSKs
Externí odkaz:
https://doaj.org/article/c73ddba187584401b4479a02130c81cf
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Recent literature has ascribed that the paracrine action of stem cells is mediated by exosomes. Exosomes are nano-sized extracellular vesicles (30 to 100 nm) of endocytic origin that play important roles in intercellular communication. They have the
Externí odkaz:
https://doaj.org/article/0e0e9dd6a06747c09b2b7a840b760649
Autor:
Andri K. Riau, Thet T. Aung, Melina Setiawan, Liang Yang, Gary H. F. Yam, Roger W. Beuerman, Subbu S. Venkatraman, Jodhbir S. Mehta
Publikováno v:
Pathogens, Vol 8, Iss 3, p 93 (2019)
Bacterial biofilm on medical devices is difficult to eradicate. Many have capitalized the anti-infective capability of silver ions (Ag+) by incorporating nano-silver (nAg) in a biodegradable coating, which is then laid on polymeric medical devices. H
Externí odkaz:
https://doaj.org/article/ad7d25a707e54a7397d7a346d25cdb6d
Autor:
Nur Zahirah binte M. Yusoff, Andri K. Riau, Gary H. F. Yam, Nuur Shahinda Humaira binte Halim, Jodhbir S. Mehta
Publikováno v:
Cells
Cells, Vol 11, Iss 178, p 178 (2022)
Cells, Vol 11, Iss 178, p 178 (2022)
The human corneal stroma contains corneal stromal keratocytes (CSKs) that synthesize and deposit collagens and keratan sulfate proteoglycans into the stromal matrix to maintain the corneal structural integrity and transparency. In adult corneas, CSKs
Autor:
Gary S. L. Peh, Zhenzhi Chng, Heng-Pei Ang, Terence Y. D. Cheng, Khadijah Adnan, Xin-Yi Seah, Benjamin L. George, Kah-Peng Toh, Donald T. Tan, Gary H. F. Yam, Alan Colman, Jodhbir S. Mehta
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Corneal endothelium-associated corneal blindness is the most common indication for corneal transplantation. Restorative corneal transplant surgery is the only option to reverse the blindness, but a global shortage of donor material remains an issue.
Externí odkaz:
https://doaj.org/article/87235556c9a94396802f68fd7af97ad1
Autor:
W.H. Irwin McLean, Sarah D. Atkinson, Gary H F Yam, Eleonora Maurizi, Johnny Moore, Forbes D C Manson, Chiara Serafini, Edwin H. A. Allen, David G. Courtney, Graeme C.M. Black, C.B. Tara Moore, Caroline J MacEwen, Graziella Pellegrini
PURPOSE: This study aimed to investigate the potency and specificity of short-interfering RNA (siRNA) treatment for TGFBI-Arg124Cys lattice corneal dystrophy type I (LCDI) using exogenous expression constructs in model systems and endogenous gene tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffd515f5e569f4eaf225f5994531305
https://hdl.handle.net/11380/1053714
https://hdl.handle.net/11380/1053714
Autor:
Barend F T, Hogewind, Katarina, Gaplovska-Kysela, Thomas, Theelen, Frans P M, Cremers, Gary H F, Yam, Carel B, Hoyng, Arijit, Mukhopadhyay
Publikováno v:
Molecular vision. 13
Glaucoma is the second most prevalent cause of blindness worldwide, projected to affect more than 60 million people by 2010, 75% of which represents primary open angle glaucoma (POAG). Of the three genes, namely, Myocilin (MYOC), Optineurin (OPTN), a
Publikováno v:
Anticancer research. 19(1A)
Esophageal cancer is a common cancer among ethnic Chinese. The reported incidence of esophageal cancer has increased many fold in the past decades and is apparently still rising. Nuclear matrix forms the scaffold of the nucleus and participates in va