Výsledky vyhledávání - "H F, Seigler"

MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele

Autor: N J Crowley, T L Darrow, M A Quinn-Allen, H F Seigler

Publikováno v: The Journal of Immunology. 146:1692-1699

Autologous melanoma-specific CTL recognize a common tumor-associated Ag (TAA) in the context of HLA class I antigens. We have demonstrated that HLA-A2 can be a restricting Ag and, in T cell lines homozygous for HLA-A2, that CTL can be generated by st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e6978e3f98508b7ebd166efc4a71e05
https://doi.org/10.4049/jimmunol.146.5.1692

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Validation of delayed sentinel lymph node mapping for melanoma

Autor: M F, Kalady, D C, White, R C, Fields, R E, Coleman, F R, Schuler, H F, Seigler, D S, Tyler

Publikováno v: Cancer journal (Sudbury, Mass.). 7(6)

Sentinel lymph node mapping using radiolabeled tracer and blue dye is widely accepted and applied for staging melanoma. Common practice involves injection of radiolabeled tracer on the morning of surgery. However, optimal timing of radiolabeled collo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::673bcb63b0d4d0979dab517ace7e6c49
https://pubmed.ncbi.nlm.nih.gov/11769863

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Primary chondroid melanoma

Autor: C D, Ackley, V G, Prieto, R C, Bentley, M G, Horenstein, H F, Seigler, C R, Shea

Publikováno v: Journal of cutaneous pathology. 28(9)

Malignant melanoma is notorious for the wide range of histologic patterns it can assume, among the least frequent of which is chondroid melamona.Two cases of primary chondroid melanoma of the distal lower extremity were studied. Tissue for light micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a14a9025f53609ae501cde639b025a9f
https://pubmed.ncbi.nlm.nih.gov/11553315

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Identification of higher risk thin melanomas should be based on Breslow depth not Clark level IV

Autor: S A, Owen, L L, Sanders, L J, Edwards, H F, Seigler, D S, Tyler, J M, Grichnik

Publikováno v: Cancer. 91(5)

There is good prognostic correlation for the two microstaging systems, Breslow depth and Clark level, commonly used to stage melanomas. Many investigators have reported that Breslow depth is the superior microstaging method. Although Clark level has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e6c5f67d2ed6438ad68e6fc7b440607
https://pubmed.ncbi.nlm.nih.gov/11251950

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Subungual melanoma. A review of 93 cases with identification of prognostic variables

Autor: J A, O'Leary, K R, Berend, J L, Johnson, L S, Levin, H F, Seigler

Publikováno v: Clinical orthopaedics and related research. (378)

From 1970 to 1996, 93 patients received diagnoses of subungual melanoma. Followup data were complete on all patients and reviewed with a median duration of followup of 5.2 years. This study identifies significant clinicopathologic variables that affe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2893ac210522aa3d03f16675dab4fb3e
https://pubmed.ncbi.nlm.nih.gov/10986996

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Positron emission tomography scanning in malignant melanoma

Autor: D S, Tyler, M, Onaitis, A, Kherani, A, Hata, E, Nicholson, M, Keogan, S, Fisher, E, Coleman, H F, Seigler

Publikováno v: Cancer. 89(5)

Several recent studies have demonstrated the low yield of anatomically based computed tomography scans in evaluating Stage III (American Joint Committee on Cancer) patients with malignant melanoma. The purpose of this study was to investigate the eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a5fa916f726bbad1da8d5f9c4290fb5
https://pubmed.ncbi.nlm.nih.gov/10964332

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Analysis of prognosis and disease progression after local recurrence of melanoma

Autor: X D, Dong, D, Tyler, J L, Johnson, P, DeMatos, H F, Seigler

Publikováno v: Cancer. 88(5)

Local recurrence of melanoma is associated with a grave prognosis. However, the characteristics and the mode of disease progression for patients with local recurrence have not been adequately addressed in the literature.A retrospective analysis of pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ac95d80c834963ea446f50af005346d
https://pubmed.ncbi.nlm.nih.gov/10699896

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Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity

Autor: S, Yang, C E, Vervaert, J, Burch, J, Grichnik, H F, Seigler, T L, Darrow

Publikováno v: International journal of cancer. 83(4)

Dendritic cells (DCs) are potent inducers of cytotoxic T lymphocytes (CTLs) when pulsed with an antigenic peptide or tumor lysate. In this report, we have used liposome-mediated gene transfer to examine the ability of plasmid DNA encoding the human m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fb1b60af4051fd84e63213e329480a52
https://pubmed.ncbi.nlm.nih.gov/10508491

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Timing of sentinel lymph node mapping after lymphoscintigraphy

Autor: D C, White, F R, Schuler, S K, Pruitt, D K, Culhane, H F, Seigler, R E, Coleman, D, Tyler

Publikováno v: Surgery. 126(2)

Sentinel lymph node (SLN) mapping is an effective technique for staging patients with melanoma. In an attempt to avoid reinjection of radiolabeled colloid and facilitate SLN mapping at the time of surgery, we examined whether residual radioactivity f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9021c1c968af7641b0cd8a921c67d33
https://pubmed.ncbi.nlm.nih.gov/10455878

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