Výsledky vyhledávání - "H F, Heijnen"

Expression of two gibberellin-regulated cDNAs during early flower development in tomato (Solanum lycopersicon ). Effect of grafting and paclobutrazol

Autor: George J. Wullems, P. H. F. Heijnen, K. J. P. T. Van Den Heuvel, G. W. M. Barendse

Publikováno v: Physiologia Plantarum. 108:95-100

To study the role of translocation of gibberellin (GA) intermediates or bioactive GAs from other plant parts to buds during early flower development in tomato (Solanum lycopersicon), the effect of grafting and paclobutrazol (PAC) treatment on the exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc5e0ade56d759996328466d0a892c95
https://doi.org/10.1034/j.1399-3054.2000.108001095.x

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Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin)

Autor: E U, Saelman, H K, Nieuwenhuis, K M, Hese, P G, de Groot, H F, Heijnen, E H, Sage, S, Williams, L, McKeown, H R, Gralnick, J J, Sixma

Publikováno v: Blood. 83:1244-1250

Platelet adhesion to fibrillar collagens (types I, II, III, and V) and nonfibrillar collagens (types IV, VI, VII, and VIII) was investigated in the presence of physiologic concentrations of divalent cations under conditions of stasis and flow. Under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c67fbaff5b8c6bd312d3073cac56071
https://doi.org/10.1182/blood.v83.5.1244.bloodjournal8351244

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Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules

Autor: H F, Heijnen, A E, Schiel, R, Fijnheer, H J, Geuze, J J, Sixma

Publikováno v: Blood. 94(11)

Platelet activation leads to secretion of granule contents and to the formation of microvesicles by shedding of membranes from the cell surface. Recently, we have described small internal vesicles in multivesicular bodies (MVBs) and alpha-granules, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4d5bfd140e6dc4a0c822399078a0f56
https://pubmed.ncbi.nlm.nih.gov/10572093

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A fifty percent reduction of platelet surface glycoprotein Ib does not affect platelet adhesion under flow conditions

Autor: G H, van Zanten, H F, Heijnen, Y, Wu, K M, Schut-Hese, P J, Slootweg, P G, de Groot, J J, Sixma, R, Nieuwland

Publikováno v: Blood. 91(7)

Glycoprotein (GP) Ib is an adhesion receptor on the platelet surface that binds to von Willebrand Factor (vWF). vWF becomes attached to collagens and other adhesive proteins that become exposed when the vessel wall is damaged. Several investigators h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af0a0f8138dc4382fb6fb2b4de266cf7
https://pubmed.ncbi.nlm.nih.gov/9516134

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Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules

Autor: H F, Heijnen, N, Debili, W, Vainchencker, J, Breton-Gorius, H J, Geuze, J J, Sixma

Publikováno v: Blood. 91(7)

We have used ultrathin cryosectioning and immunogold cytochemistry to study the position of alpha-granules in the endocytic and biosynthetic pathways in megakaryocytes and platelets. Morphologically, we distinguished three types of granules; so-calle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f23ac7170d78fc72f28b29dfc94793c5
https://pubmed.ncbi.nlm.nih.gov/9516129

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Platelet adhesion to fibronectin in flow: the importance of von Willebrand factor and glycoprotein Ib

Autor: S, Beumer, H F, Heijnen, M J, IJsseldijk, E, Orlando, P G, de Groot, J J, Sixma

Publikováno v: Blood. 86(9)

We describe glycoprotein (GP) Ib as a mediator of adhesion to fibronectin, specifically in flow. A monoclonal antibody (MoAb) directed to the von Willebrand factor (vWF)-binding site on this receptor or the absence of this receptor on the platelet me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3015123367e81b862e7561c685a86ade
https://pubmed.ncbi.nlm.nih.gov/7579450

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Biochemical and immunohistochemical characteristics of CD62 and CD63 monoclonal antibodies. Expression of GMP-140 and LIMP-CD63 (CD63 antigen) in human lymphoid tissues

Autor: M J, Metzelaar, H J, Schuurman, H F, Heijnen, J J, Sixma, H K, Nieuwenhuis

Publikováno v: Virchows Archiv. B, Cell pathology including molecular pathology. 61(4)

During platelet secretion granule membrane glycoproteins are translocated to the plasma membrane. We report here the biochemical and immunohistochemical characterization of a panel of platelet-secretion-specific, CD62 and CD63 monoclonal antibodies (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc28b1905d455eb00ed0fab57f97a0ef
https://pubmed.ncbi.nlm.nih.gov/1723556

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Morphology of the hemostatic plug in human skin wounds: transformation of the plug

Autor: J, Wester, J J, Sixma, J J, Geuze, H F, Heijnen

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 41(2)

The transformation of hemostatic plugs in human skin wounds was studied in vivo after bleeding had stopped. Standardized bleeding time incisions were made on the dorsal side of the forearm of four normal male volunteers. The wounds were excised by pu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::985e45aba8b98e9b11440748f5253c02
https://pubmed.ncbi.nlm.nih.gov/459434

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