Zobrazeno 1 - 10
of 135
pro vyhledávání: '"H F, Dvorak"'
Publikováno v:
European Journal of Cancer. 32:2467-2473
Autor:
L F, Brown, A J, Guidi, S J, Schnitt, L, Van De Water, M L, Iruela-Arispe, T K, Yeo, K, Tognazzi, H F, Dvorak
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(5)
The generation of vascular stroma is essential for solid tumor growth and involves stimulatory and inhibiting factors as well as stromal components that regulate functions such as cellular adhesion, migration, and gene expression. In an effort to obt
Publikováno v:
Microcirculation (New York, N.Y. : 1994). 6(1)
The goal of these studies was to define the anatomic pathways by which circulating macromolecules extravasate from the hyperpermeable microvessels that supply tumors and from normal venules that have been rendered hyperpermeable by vasoactive mediato
Publikováno v:
Current topics in microbiology and immunology. 237
This Chapter has reviewed the literature concerning VPF/VEGF as a potent vascular permeabilizing cytokine. In accord with this important role, microvessels have been found to be hyperpermeable to plasma proteins and other circulating macromolecules a
Publikováno v:
Cancer research. 58(6)
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) is a multifunctional cytokine and growth factor that has important roles in both pathological and physiological angiogenesis. VPF/VEGF induces vascular hyperpermeability, cell
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 77(6)
Increased microvessel density has been described in squamous cell carcinoma of the head and neck and is related to patient prognosis. The factors responsible for the angiogenesis have not been identified. Vascular permeability factor (VPF), also know
Publikováno v:
Cancer. 80(10)
Prior studies have indicated that ductal carcinoma in situ (DCIS) lesions are capable of inducing a vascular stroma. However, the mechanisms responsible for angiogenesis in DCIS currently are not defined. The goal of this study was to determine the r
Autor:
M L, Iruela-Arispe, H F, Dvorak
Publikováno v:
Thrombosis and haemostasis. 78(1)
Angiogenesis, the formation of new blood vessels from a pre-existing vasculature, is tightly regulated in normal adults. Under physiological circumstances, angiogenesis occurs in only a few instances; e.g., the female reproductive system in response
Publikováno v:
EXS. 79
VPF/VEGF is a multifunctional cytokine that contributes to angiogenesis by both direct and indirect mechanisms. On the one hand, VPF/VEGF stimulates the endothelial cells lining nearby microvessels to proliferate, to migrate and to alter their patter
Publikováno v:
The American journal of pathology. 148(6)
The mouse ovarian ascites tumor, MOT, and mammary ascites tumor, TA3/St, served as models to follow changes in hyaluronan levels during tumor growth, attachment, and invasion. Subsequent to introduction of tumor cells into the peritoneal cavity, hyal