Zobrazeno 1 - 10
of 11
pro vyhledávání: '"H E, Saqr"'
Publikováno v:
Neurochemical Research. 31:1171-1180
An increasing amount of evidence indicates that the disialoganglioside GD3 is involved in apoptosis in many cell lines. Our previous studies demonstrated that endogenous GD3 expression induced apoptosis in U-1242 MG glioma cells transfected with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b56366d79d6a211c51ef2d71ab57e49
https://doi.org/10.1007/s11064-006-9147-2
https://doi.org/10.1007/s11064-006-9147-2
Publikováno v:
Journal of Neurochemistry. 61:395-441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671686ae425edb3796799aec25c6dd88
https://doi.org/10.1111/j.1471-4159.1993.tb02140.x
https://doi.org/10.1111/j.1471-4159.1993.tb02140.x
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 65:152-161
Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) induces apoptosis in U-1242 MG cells. To investigate the molecular events involved in this process, we studied the effects of TRAIL on the localization within membrane fractions of molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287511f74bf768c2d7fe52839d036db8
https://doi.org/10.1097/01.jnen.0000199574.86170.80
https://doi.org/10.1097/01.jnen.0000199574.86170.80
Publikováno v:
Journal of Neurochemistry. 96:1301-1314
GD3 ganglioside induces apoptosis in several cell types, but the molecular events through which this occurs are largely unknown. We investigated the apoptotic effects of GD3 expression using U-1242 MG glioblastoma cells, as these cells synthesize alm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72779f9ebb7b1e4c8bb2855581496557
https://doi.org/10.1111/j.1471-4159.2005.03640.x
https://doi.org/10.1111/j.1471-4159.2005.03640.x
Publikováno v:
Neurochemistry International. 35:411-422
PDGF-BB induces a rapid, sustained increase in intracellular calcium levels in U-1242 MG cells. We used several calcium channel blockers to identify the types of channels involved. L channel blockers (verapamil, nimodipine, nicardipine, nitrendipine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b971a20e6cdd49da22f1179401a0d0
https://doi.org/10.1016/s0197-0186(99)00092-3
https://doi.org/10.1016/s0197-0186(99)00092-3
Publikováno v:
Neurochemical Research. 20:1389-1395
In this study we investigated the responses of intracellular calcium ([Ca2+]i) and protein kinase C (PKC) to PDGF in U-1242 MG cells. PDGF-BB stimulated [3H]PDBu binding approximately 2-3 fold. This response was inhibited by preincubating the cells w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878fb26beb8561209c8f11832576bd84
https://doi.org/10.1007/bf00992515
https://doi.org/10.1007/bf00992515
Publikováno v:
Journal of Neuro-Oncology. 24:65-73
Gangliosides are a family of glycolipids that are present at the cell surface of all mammalian cells. Patterns of gangliosides are different in gliomas than normal brain, and exogenously added gangliosides affect the growth of cultured glioma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47427a660ccf587c7816c2c12fb4bc63
https://doi.org/10.1007/bf01052661
https://doi.org/10.1007/bf01052661
Autor:
Peter C. Burger, Dennis K. Pearl, Janet L. Oblinger, Allan J. Yates, Thomas W. Prior, Cynthia L. Boardman, Bernd W. Scheithauer, Robert B. Jenkins, H. E. Saqr
Publikováno v:
Neuropathology and applied neurobiology. 32(4)
Glioblastoma multiforme (GBM) is the most common and aggressive primary human brain tumour in adults with an average survival of 11 months. The 2-year survival is less than 10%, and only a small proportion of patients are alive at 3 years. Despite im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b21e8f4db96e26d02f5fd3e99db5e6
https://pubmed.ncbi.nlm.nih.gov/16866986
https://pubmed.ncbi.nlm.nih.gov/16866986
Publikováno v:
Journal of neurochemistry. 96(5)
GD3 ganglioside induces apoptosis in several cell types, but the molecular events through which this occurs are largely unknown. We investigated the apoptotic effects of GD3 expression using U-1242 MG glioblastoma cells, as these cells synthesize alm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::210769ce4c7159e5fd90fc0caee36377
https://pubmed.ncbi.nlm.nih.gov/16441517
https://pubmed.ncbi.nlm.nih.gov/16441517
Publikováno v:
Annals of the New York Academy of Sciences. 845
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e14a244ea78a5f048d32bcf218085c
https://pubmed.ncbi.nlm.nih.gov/9668383
https://pubmed.ncbi.nlm.nih.gov/9668383