Zobrazeno 1 - 10
of 112
pro vyhledávání: '"H E, Meyer"'
Autor:
Teri E. Klein, Li Gong, Michelle Whirl-Carrillo, Chiara Jeiziner, Katja Suter, T D Szucs, H. E. Meyer zu Schwabedissen, Kurt E. Hersberger, U Wernli, Julia M. Barbarino
Publikováno v:
The Pharmacogenomics Journal
Implementation of pharmacogenetics (PGx) and individualization of drug therapy is supposed to obviate adverse drug reactions or therapy failure. Health care professionals (HCPs) use drug labels (DLs) as reliable information about drugs. We analyzed t
Akademický článek
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Autor:
D. Canoy, N. C. Harvey, D. Prieto-Alhambra, C. Cooper, H. E. Meyer, B. O. Åsvold, M. Nazarzadeh, K. Rahimi
Publikováno v:
Osteoporosis International. 33:2241-2241
Publikováno v:
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 29(11)
The association between alcohol consumption and hip fracture differed by gender: Men aged 30-59 years drinking frequently or 14+ gl/week had higher risk than moderate drinkers. No significant association was seen in older men. Women not drinking alco
Akademický článek
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Autor:
A Nassif, Heyo K. Kroemer, Zeruesenay Desta, Dieter Lütjohann, H E Meyer zu Schwabedissen, Werner Siegmund, Stefan Oswald, C. Bresser, Evan T. Ogburn, M Marinova, C. Spielhagen, Matthias Nauck, Christiane Modess
Publikováno v:
Clinical Pharmacology & Therapeutics. 92:103-111
Nuclear receptors such as the constitutive androstane receptor (CAR) are central factors that link drug exposure to the activities of drug metabolism and elimination. In order to determine the in vivo effects of efavirenz, a CAR activator, the expres
Autor:
Dave Freeman, H E Meyer zu Schwabedissen, Richard B. Kim, George K. Dresser, Rommel G. Tirona, Bradley L. Urquhart, Murray J. Cutler, Thomas J. Velenosi, Brenda F. Leake
Publikováno v:
The Journal of Clinical Pharmacology. 52:530-542
Mesna and its dimer, dimesna, are coadministered for mitigation of ifosfamide- and cisplatin-induced toxicities, respectively. Dimesna is selectively reduced to mesna in the kidney, producing its protective effects. In vitro screens of uptake and eff
Autor:
Matthias Nauck, H E Meyer zu Schwabedissen, C. Brinkman, Reiner Biffar, Henry Völzke, C. O. Schmidt, Thomas Kocher, Hans-Jörgen Grabe, Olaf Bernhardt, Christian Schwahn, Alexander Teumer
Publikováno v:
European Journal of Pain. 16:878-889
Background Variations within the catechol-O-methyltransferase (COMT) gene have been associated with pain severity in temporomandibular disorders (TMDs). Psychological factors such as personal conflicts, life stress and depression, are well known to b
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 135:133-144
Pharmacogenomics investigates inherited differences in drug responses including beneficial and adverse reactions. While a considerable amount of evidence for genetic influences on drug responses has been accumulated within the last decade, predominan
Publikováno v:
Journal of Biological Chemistry. 275:34068-34072
In yeast, the endoplasmic reticulum membrane proteins Sec11p and Spc3p are essential for the cleavage of signal peptides of nascent polypeptide chains during their passage through translocation sites. Genetic and biochemical experiments demonstrate t