Immunogenic efficacy of differently produced recombinant vaccines candidates against Pseudomonas aeruginosa infections

Autor: Erika Hundt, H Schmidt-Pilger, H Domdey, Bernhard Knapp, Josef Gabelsberger, S Bauernsachs, Uwe Lenz, B U von Specht

Publikováno v: Journal of Biotechnology. 83:3-12

Three different variants of the recombinant hybrid outer membrane protein OprF (aa 190-342)-OprI (aa 21-83) could be obtained in high yield after expression in Escherichia coli. The hybrid protein was modified N terminally, either with a minimal hist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d59a4596abd328177c59f57830f4478
https://doi.org/10.1016/s0168-1656(00)00311-4

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X

Autor: A. Hennemann, C P Hollenberg, Eckhard Boles, André Goffeau, K D Entian, K. Heumann, A. Baur, Despina Alexandraki, M. de Haan, C. Katsoulou, C. Jacq, L. A. Grivell, C. Cziepluch, F. Galibert, H. Domdey, F. Coster, P. Durand, J. C. Jauniaux, N. Chalwatzis, Meng-Er Huang, C. J. Herbert, L Karpfinger-Hartl, F. Hilger, J. C. Chuat, M. Gatius

Publikováno v: The EMBO Journal. 15:2031-2049

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome X (745 442 bp) reveals a total of 379 open reading frames (ORFs), the coding region covering approximately 75% of the entire sequence. One hundred and eighteen ORFs (31%) corresp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800e37936971b5b64609600987cbec78
https://doi.org/10.1002/j.1460-2075.1996.tb00557.x

Complete DNA sequence of yeast chromosome II

Autor: H, Feldmann, M, Aigle, G, Aljinovic, B, André, M C, Baclet, C, Barthe, A, Baur, A M, Bécam, N, Biteau, E, Boles, T, Brandt, M, Brendel, M, Brückner, F, Bussereau, C, Christiansen, R, Contreras, M, Crouzet, C, Cziepluch, N, Démolis, T, Delaveau, F, Doignon, H, Domdey, S, Düsterhus, E, Dubois, B, Dujon, M, El Bakkoury, K D, Entian, M, Feurmann, W, Fiers, G M, Fobo, C, Fritz, H, Gassenhuber, N, Glandsdorff, A, Goffeau, L A, Grivell, M, de Haan, C, Hein, C J, Herbert, C P, Hollenberg, K, Holmstrøm, C, Jacq, M, Jacquet, J C, Jauniaux, J L, Jonniaux, T, Kallesøe, P, Kiesau, L, Kirchrath, P, Kötter, S, Korol, S, Liebl, M, Logghe, A J, Lohan, E J, Louis, Z Y, Li, M J, Maat, L, Mallet, G, Mannhaupt, F, Messenguy, T, Miosga, F, Molemans, S, Müller, F, Nasr, B, Obermaier, J, Perea, A, Piérard, E, Piravandi, F M, Pohl, T M, Pohl, S, Potier, M, Proft, B, Purnelle, M, Ramezani Rad, M, Rieger, M, Rose, I, Schaaff-Gerstenschläger, B, Scherens, C, Schwarzlose, J, Skala, P P, Slonimski, P H, Smits, J L, Souciet, H Y, Steensma, R, Stucka, A, Urrestarazu, Q J, van der Aart, L, van Dyck, A, Vassarotti, I, Vetter, F, Vierendeels, S, Vissers, G, Wagner, P, de Wergifosse, K H, Wolfe, M, Zagulski, F K, Zimmermann, H W, Mewes, K, Kleine

Publikováno v: The EMBO Journal. 13:5795-5809

In the framework of the EU genome-sequencing programmes, the complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome II (807 188 bp) has been determined. At present, this is the largest eukaryotic chromosome entirely sequenced. A total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be972711eaf43a96271e6ad476de1f6b
https://doi.org/10.1002/j.1460-2075.1994.tb06923.x

Protection of immunosuppressed mice against infection with Pseudomonas aeruginosa by monoclonal antibodies to outer membrane protein OprI

Autor: H Domdey, M. Duchêne, R. Rahner, A. Eckhardt, B U von Specht

Publikováno v: Infection. 18:242-245

Two monoclonal antibodies (mAbs) designated 2A1 and 6A4 which had been shown to be directed against Pseudomonas aeruginosa outer membrane lipoprotein I were tested in cyclophosphamide treated mice for their protective ability against P. aeruginosa in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32a65fcf30dd00c9140bfd4fe76f775
https://doi.org/10.1007/bf01643398

Safety and immunogenicity of an intranasal Pseudomonas aeruginosa hybrid outer membrane protein F-I vaccine in human volunteers

Autor: Gabriele Köhler, M Larbig, Klaus-Dieter Hungerer, J Freihorst, E. Mansouri, Bernhard Knapp, Josef Gabelsberger, B U von Specht, H Domdey, Burkhard Tümmler, Erika Hundt

Publikováno v: Vaccine. 19(17-19)

A hybrid protein [Met-Ala-(His)(6) OprF(190-342)-OprI(21-83)] consisting of the mature outer membrane protein I (OprI) and amino acids 190-342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni(2+) chelate-affinity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521712fba1558f9f86972e4462532222
https://pubmed.ncbi.nlm.nih.gov/11257350