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pro vyhledávání: '"H Dolphin"'
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Akademický článek
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Publikováno v:
Age and Ageing. 50:ii9-ii41
Background Aducanumab, the first monoclonal antibody directed against amyloid beta peptide has recently been licensed for use by the FDA for treatment of patients with mild cognitive impairment (MCI) due to Alzheimer’s Disease (ad) or mild ad demen
Autor:
H Dolphin, A Fallon, C McHale, J Dookhy, D O'Neill, T Coughlan, S Coveney, S O'Dowd, S P Kennelly
Publikováno v:
Age and Ageing. 50:ii9-ii41
Background CSF (cerebrospinal fluid) biomarkers [amyloid- beta-42 (AB-42), phosphorylated tau (p-tau)] are increasingly used in supporting clinical diagnosis of Alzheimer’s Disease (AD). Both elevated CSF p-tau and reduced AB-42 are necessary for p
Publikováno v:
Age and Ageing. 50:ii9-ii41
Background It is now well established that VRF place immense burden on cognition, including white matter changes, decreased cerebral perfusion and neuro-inflammation. An innovative Brain Health Clinic (BHC) was developed aligned to a specialist memor
Autor:
H Dolphin, A Dyer, M Domsa, D McNally, M Doyle, J Keating, C Noonan, C McGuinn, L Ahern, A Murphy, N Malone, SP Kennelly
Publikováno v:
Age and Ageing. 51
Background An important consequence of population ageing has been the increasing number of older adults who live alone. According to TILDA data, older adults with the lowest levels of education tend to experience most social isolation and there is a
219 A SOLITARY AWARENESS - PROFILING TIME TO RECOGNITION OF MEMORY LOSS IN A TERTIARY MEMORY SERVICE
Publikováno v:
Age and Ageing. 51
Background Approximately 64,000 people live with dementia in Ireland with expected increases to 150,000 by 2045. Best practice recommends that patients benefit from timely diagnosis. Whilst the presence of cognitive impairment should prompt early ref
Autor:
A Dyer, H Dolphin, E Laird, L Hoey, H McNulty, C Hughes, M Ward, JJ Strain, M O'Kane, F Tracey, A Molloy, C Cunningham, K McCarroll
Publikováno v:
Age and Ageing. 51
Background Impaired mobility is associated with incident cognitive impairment and dementia. However, the complex bi-directional temporal relationships between subtle impairments in neuropsychological performance, mobility trajectories and falls is po
Publikováno v:
Age and Ageing. 51
Background People living with mild cognitive symptoms often require clarity on the underlying aetiology of their symptoms, and with the advent of disease modifying therapies for Alzheimer’s Disease (AD), establishing diagnostic accuracy for amyloid
Akademický článek
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