Zobrazeno 1 - 10
of 99
pro vyhledávání: '"H Döbeli"'
Publikováno v:
The Journal of Immunology. 144:1497-1503
The multiplication of Plasmodium falciparum within RBC is energy-dependent and the glucose consumption of infected RBC is increased more than 50 times over the consumption of normal RBC. High levels of glycolytic enzymes such as fructose-1,6-diphosph
Publikováno v:
European journal of biochemistry. 268(22)
NMR studies of amyloid beta-peptides (A beta) in aqueous solution provide a novel way in which to characterize the apparent Alzheimer's disease-related conformational polymorphism of A beta. In the aqueous medium, neither of the polypeptides A beta(1
Publikováno v:
The European journal of neuroscience. 14(6)
Astrocytes and microglia are closely associated with amyloid plaques in Alzheimer's disease (AD). Microglia constitute the first barrier surrounding plaques, although they seem to be unable to remove them efficiently. We evaluated the reaction of mic
Autor:
B, Bohrmann, L, Tjernberg, P, Kuner, S, Poli, B, Levet-Trafit, J, Näslund, G, Richards, W, Huber, H, Döbeli, C, Nordstedt
Publikováno v:
The Journal of biological chemistry. 274(23)
We report that certain plasma proteins, at physiological concentrations, are potent inhibitors of amyloid beta-peptide (Abeta) polymerization. These proteins are also present in cerebrospinal fluid, but at low concentrations having little or no effec
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 31
Publikováno v:
Biochemistry. 31(35)
1H, 13C, and 15N NMR assignments of the protein backbone of human interferon-gamma, a homodimer of 31.4 kDa, have been made using the recently introduced three-dimensional (3D) triple-resonance NMR techniques. It is shown that, despite the approximat
Publikováno v:
Acta Leidensia. 60(1)
P. falciparum lacks a functional citric acid cycle. Unlike most tissues of the mammalian host, it is totally dependent on glycolysis for energy generation. A compound which selectively inhibits the parasite's ATP-generating machinery is therefore a p
Publikováno v:
European Neuropsychopharmacology. 4:229-230
Proteolytic production and deposition of β-amyloid peptide is an early sign of pathology in the brains of Alzheimer's disease patients. This may result not only in disturbance of β-amyloid precursor protein (β-APP) functions but also in accumulati
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Publikováno v:
Antimicrobial Agents and Chemotherapy. 18:111-117
O-Acetyl-L-serine sulfhydrylase catalyzes the final step in the biosynthesis of cysteine from H2S and O-acetyl-L-serine in the fungus Cephalosporsium acremonium, a cephalosporin C-producing organism. We separated this enzyme from the closely related