Zobrazeno 1 - 10
of 22
pro vyhledávání: '"H D, Gresham"'
Autor:
H D Gresham, Robert M. Senior, Albert E. Chung, Jyh-Cheng Hsieh, Li-Jin Dong, Gail L. Griffin, Irene L. Graham
Publikováno v:
Journal of Biological Chemistry. 271:30587-30594
Extracellular matrix proteins activate neutrophils to up-regulate many physiologic functions that are necessary at sites of tissue injury. To elucidate the ligand-receptor interactions that mediate these functions, we examined neutrophil activation b
Publikováno v:
Journal of Biological Chemistry. 267:13895-13902
The ligand binding specificity of the leukocyte response integrin (LRI) expressed by polymorphonuclear leukocyte (PMN) was investigated by examining its interaction with two adhesion motifs within fibrinogen: the alpha chain sequence RGD and the gamm
Publikováno v:
Journal of Clinical Investigation. 88:588-597
Stimulation of PMN with inflammatory mediators markedly augments Fc and CR1 receptor-mediated ingestion. However, CD11/CD18-deficient PMN from three patients with complete leukocyte adhesion deficiency (LAD) failed to recruit phagocytic function in r
Publikováno v:
The Journal of Immunology. 146:3911-3921
Patients with systemic autoimmune diseases such as SLE and rheumatoid arthritis have increased rates of morbidity and mortality caused by infection. Although this increased risk of infection has been primarily attributed to therapeutic immuno-suppres
Publikováno v:
The Journal of Cell Biology
Phagocytosis by monocytes or neutrophils can be enhanced by interaction with several proteins or synthetic peptides containing the Arg-Gly-Asp sequence. Recently we showed that an mAb, B6H12, specifically inhibited this enhancement of neutrophil phag
Publikováno v:
The Journal of biological chemistry. 271(48)
Extracellular matrix proteins activate neutrophils to up-regulate many physiologic functions that are necessary at sites of tissue injury. To elucidate the ligand-receptor interactions that mediate these functions, we examined neutrophil activation b
Publikováno v:
The Journal of clinical investigation. 90(6)
Entactin is an integral component of basement membranes that plays a major role in basement membrane assembly through its ability to bind avidly to both laminin and type IV collagen. Because neutrophil (PMN) interactions with entactin have not been e
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(8)
Integrin-associated protein (IAP) is a 50-kDa intrinsic membrane protein that is involved in signal transduction during neutrophil activation by a variety of Arg-Gly-Asp-containing ligands. However, IAP does not itself directly bind these ligands, wh
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(11)
Patients with systemic autoimmune diseases such as SLE and rheumatoid arthritis have increased rates of morbidity and mortality caused by infection. Although this increased risk of infection has been primarily attributed to therapeutic immuno-suppres
Publikováno v:
The Journal of biological chemistry. 265(14)
Human neutrophils (PMN) possess at least two distinct mechanisms for the ingestion of IgG-opsonized pathogens; one is independent of and the other is dependent on products of the respiratory burst. Oxidant-mediated ingestion is not induced by exposur