Zobrazeno 1 - 10
of 150
pro vyhledávání: '"H Coenraad Hemker"'
Autor:
Romy M W Kremers, Marie-Claire Kleinegris, Marisa Ninivaggi, Bas de Laat, Hugo Ten Cate, Ger H Koek, Rob J Wagenvoord, H Coenraad Hemker
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177020 (2017)
Impaired coagulation factor synthesis in cirrhosis causes a reduction of most pro- and anticoagulant factors. Cirrhosis patients show no clear bleeding or thrombotic phenotype, although they are at risk for both types of hemostatic event. Thrombin ge
Externí odkaz:
https://doaj.org/article/1074baf786d4412cbed9327212ed6273
Autor:
Romy M W Kremers, Abdulrahman B O Mohamed, Leonie Pelkmans, Salwa Hindawi, H Coenraad Hemker, H Bas de Laat, Dana Huskens, Raed Al Dieri
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141491 (2015)
Individuals with blood group O have a higher bleeding risk than non-O blood groups. This could be explained by the lower levels of FVIII and von Willebrand Factor (VWF) levels in O individuals. We investigated the relationship between blood groups, t
Externí odkaz:
https://doaj.org/article/cf843ff520904d30bc8fdaf0bf7c446f
Autor:
Romy M.W. Kremers, Stéphane Zuily, Hilde Kelchtermans, Tessa C. Peters, Saartje Bloemen, Véronique Regnault, H. Coenraad Hemker, Philip G. de Groot, Denis Wahl, Bas de Laat
Publikováno v:
Blood Advances, Vol 2, Iss 11, Pp 1315-1324 (2018)
Abstract: Antiphospholipid syndrome (APS) is a condition in which the presence of antibodies against phospholipid-binding proteins is associated with thrombophilia and/or pregnancy morbidity. Although antiphospholipid antibodies have anticoagulant ch
Externí odkaz:
https://doaj.org/article/7767c9c787474847b0d80b489c894b54
Autor:
Hugo ten Cate, H. Coenraad Hemker
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 8 (2016)
Externí odkaz:
https://doaj.org/article/f83440b293374683bd8bcf34372d7e66
Autor:
H. Coenraad Hemker, Roy Schrijver, Chris P. M. Reutelingsperger, Danielle M. H. Beurskens, Joram Huckriede, Gerry A. F. Nicolaes
Publikováno v:
Thrombosis and Haemostasis. 120:1371-1383
Heparins represent one of the most frequently used pharmacotherapeutics. Discovered around 1926, routine clinical anticoagulant use of heparin was initiated only after the publication of several seminal papers in the early 1970s by the group of Kakka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26df757fbd1bb6c4551e6d439e730b9
https://doi.org/10.1055/s-0040-1715460
https://doi.org/10.1055/s-0040-1715460
Autor:
H. Coenraad Hemker, Henri M. H. Spronk, Hugo ten Cate, Yvonne M. C. Henskens, Anne Marije Hulshof
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2590, p 2590 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2590, p 2590 (2021)
Fibrinogen is a well-known risk factor for arterial and venous thrombosis. Its function is not restricted to clot formation, however, as it partakes in a complex interplay between thrombin, soluble plasma fibrinogen, and deposited fibrin matrices. Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c8f84f3c8bd414b1a6abd7b1a87f2c
https://pubmed.ncbi.nlm.nih.gov/33806700
https://pubmed.ncbi.nlm.nih.gov/33806700
Publikováno v:
Haematologica, Vol 98, Iss 4 (2013)
Anticoagulation by a standard dosage of an inhibitor of thrombin generation presupposes predictable pharmacokinetics and pharmacodynamics of the anticoagulant. We determined the inter-individual variation of the effect on thrombin generation of a fix
Externí odkaz:
https://doaj.org/article/7efa9f21e7e84d2e97664618045224e2
Autor:
H. Coenraad Hemker, Bas de Laat, Philip G. de Groot, Hilde Kelchtermans, Saartje Bloemen, Romy Kremers, Stéphane Zuily, Denis Wahl, Tessa Peters, Véronique Regnault
Publikováno v:
Blood advances, 2(11), 1315-1324. The American Society of Hematology
Antiphospholipid syndrome (APS) is a condition in which the presence of antibodies against phospholipid-binding proteins is associated with thrombophilia and/or pregnancy morbidity. Although antiphospholipid antibodies have anticoagulant characterist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c3b4d2df9b1da1ce2005738af7b8f7
https://cris.maastrichtuniversity.nl/en/publications/6c04e989-a414-4e5a-9c25-c53db2ae508e
https://cris.maastrichtuniversity.nl/en/publications/6c04e989-a414-4e5a-9c25-c53db2ae508e
Publikováno v:
Thrombosis Journal, Vol 16, Iss 1, Pp 1-4 (2018)
Thrombosis Journal, 16:10. BioMed Central Ltd
Thrombosis Journal
Thrombosis Journal, 16:10. BioMed Central Ltd
Thrombosis Journal
Accurate thrombin generation determination by calibrated automated thrombinography can be sustained when reducing the plasma and reagent volumes up to half, but not for higher reductions or plasma dilutions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d6f6909ed5fba3fb77c5b6963a65f3
http://link.springer.com/article/10.1186/s12959-018-0164-6
http://link.springer.com/article/10.1186/s12959-018-0164-6
Autor:
Thomas Lecompte, Denis Wahl, Christine Perret-Guillaume, H. Coenraad Hemker, Patrick Lacolley, Véronique Regnault
Publikováno v:
Haematologica, Vol 92, Iss 5 (2007)
Interference of antiphospholipid antibodies (aPL) with coagulation was investigated in 40 aPL-patients (24 with thrombosis) using thrombography. Impairment of the activated protein C anticoagulant pathway was partially offset by the genuine anticoagu
Externí odkaz:
https://doaj.org/article/1da217e8d29b4aa18628d7bddfdb2991