Zobrazeno 1 - 10
of 302
pro vyhledávání: '"H C Palfrey"'
Autor:
H C Palfrey, M M Wert
Publikováno v:
Biochemical Journal. 352:175-182
The mechanisms whereby nerve growth factor (NGF) and basic fibroblast growth factor (bFGF) block apoptosis in serum-deprived PC12 cells were investigated. NGF, but not bFGF, strongly activated Akt/protein kinase B, a downstream effector of phosphoino
Publikováno v:
Journal of Biological Chemistry. 269:10581-10589
PC12 cells possess a bumetanide-sensitive Na/K/2Cl cotransport system similar to that found in other cell types. Between 10-15% of the total 86Rb influx in these cells is mediated by this pathway under normal conditions. The cotransporter has affinit
Publikováno v:
Journal of Biological Chemistry. 269:7772-7776
A M(r) 100,000 phosphoprotein in the corpus luteum was identified as elongation factor 2 (EF-2). Since prolactin (PRL) is necessary for optimal luteal development and protein synthesis, we determined whether this hormone affects the content and/or ph
Publikováno v:
American Journal of Physiology-Cell Physiology. 266:C284-C292
Over time, Xenopus laevis changed from producing stage V and VI oocytes with little native Na(+)-K(+)-2Cl- cotransport activity to those with substantial activity. In oocytes with high endogenous activity, K+ uptake, using the tracer 86Rb+ was approx
Publikováno v:
Science. 8/2/2024, Vol. 385 Issue 6708, p544-549. 6p. 1 Color Photograph, 2 Diagrams.
Autor:
E. B. Pewitt, H. C. Palfrey
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 425:321-328
Na(+)-K(+)-2Cl- cotransport activity has previously been shown to depend on both intracellular ATP and Mg2+, but the mechanisms remain unknown. Cotransport in avian erythrocytes can be stimulated by a variety of agents including cAMP and permeant ser
Publikováno v:
Journal of Biological Chemistry. 268:13422-13433
Calmodulin-dependent protein kinase III (CaM kinase III) phosphorylates and thereby inactivates eukaryotic elongation factor-2 (EF-2). This enzyme, purified to homogeneity from either rabbit reticulocytes or rat pancreas, had similar properties: it m
Publikováno v:
Journal of Biological Chemistry. 268:11176-11187
Kinesin is an ubiquitous heterotetrameric microtubule-based motor which translocates membrane-bound organelles. Since organelle motility and motor protein function can be regulated by components of signaling pathways, the ability of purified bovine b
Publikováno v:
Journal of Biological Chemistry. 265:20747-20756
The Na/K/2Cl cotransport system in the avian erythrocyte can be activated by agents that raise intracellular cAMP suggesting the involvement of cAMP-dependent protein kinase (cAMP-PK) in its regulation. Another group of stimuli including fluoride and
Publikováno v:
Journal of Biological Chemistry. 265:14364-14370
The relationship between Na/K/2Cl cotransport activation in duck erythrocytes and binding of the diuretic [3H]bumetanide to isolated membranes from stimulated cells has been assessed. Cotransport was activated by either cAMP-dependent (norepinephrine