Zobrazeno 1 - 10
of 19
pro vyhledávání: '"H C Kelker"'
Publikováno v:
The Journal of Immunology. 152:4139-4148
An HIV-1 envelope protein gp120-derived monomeric peptide (amino acid residues 419-439) and its homologous multiple chain peptide (MCP) construct were compared for immunogenicity in mice. The Abs stimulated by the MCP recognized epitopes on the MCP t
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8555 (2010)
PLoS ONE, Vol 5, Iss 1, p e8555 (2010)
Background Novel strategies are needed for the elicitation of broadly neutralizing antibodies to the HIV envelope glycoprotein, gp120. Experimental evidence suggests that combinations of antibodies that are broadly neutralizing in vitro may protect a
Publikováno v:
AIDS Research and Human Retroviruses. 8:1355-1359
A comparison of the proliferative responses of lymphocytes to human immunodeficiency virus (HIV) antigens from long-term, seronegative heterosexual partners of HIV-infected subjects, from normal unexposed controls and from healthy seropositive hetero
Publikováno v:
Retrovirology, Vol 6, Iss Suppl 3, p P84 (2009)
Retrovirology
Retrovirology
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(8)
An HIV-1 envelope protein gp120-derived monomeric peptide (amino acid residues 419-439) and its homologous multiple chain peptide (MCP) construct were compared for immunogenicity in mice. The Abs stimulated by the MCP recognized epitopes on the MCP t
Autor:
Berish Y. Rubin, Bharat B. Aggarwal, E Rinderknecht, Junming Le, Donna S. Stone-Wolff, D. Henriksen-Destefano, Y K Yip, Jan Vilcek, H C Kelker
Publikováno v:
The Journal of Experimental Medicine
Crude preparations of interferon (IFN)-gamma derived from human peripheral blood leukocyte (PBL) cultures induced with 12-O-tetra-decanoylphorbol-13-acetate (TPA) and phytohemagglutinin (PHA) were more cytotoxic to HeLa cells than partially purified
Autor:
H C Kelker, M E Pullman
Publikováno v:
Journal of Biological Chemistry. 254:5364-5371
Publikováno v:
The Journal of Immunology. 132:1300-1304
Monoclonal antibody GIF-1 was found to neutralize human natural immune interferon (IFN-gamma), but not Escherichia coli-derived recombinant IFN-gamma. In addition, GIF-1 antibody failed to immunoprecipitate 125I-labeled recombinant IFN-gamma, whereas
Publikováno v:
Journal of Biological Chemistry. 258:8010-8013
Highly purified human interferon (IFN)-gamma was treated with a preparation of mixed glycosidases in order to evaluate the effect of carbohydrate depletion on its biological activity, isoelectric point, and molecular size. Glycosidase treatment did n
Autor:
Bharat B. Aggarwal, H C Kelker, D. Henriksen-Destefano, Joel D. Oppenheim, Donna S. Stone-Wolff, Henry C. Stevenson, Jan Vilcek
Publikováno v:
International Journal of Cancer. 36:69-73
Cultures of human peripheral blood leukocytes (PBL) induced with phytohemagglutinin (PHA) and the phorbol ester 12-0-tetradecanoylphorbol 13-acetate (TPA) produced two types of cytotoxic proteins, indistinguishable in the in vitro assay employing mur