Zobrazeno 1 - 10
of 62
pro vyhledávání: '"H C, van der Heyde"'
Autor:
Patrick R. Flaherty, Joan Batchelder, C. Wong, H C van der Heyde, William P. Weidanz, GayeLyn LaFleur
Publikováno v:
Experimental Parasitology. 111:97-104
Our previous observation that B-cell-deficient J H - / - mice utilize T cell-dependent immunity to suppress acute Plasmodium chabaudi adami -induced malaria but then develop chronic low-level parasitemia prompted this study of control mechanisms for
Publikováno v:
The Journal of Immunology. 157:2096-2102
We examined the cellular and molecular basis of the proliferative response of human gamma delta T cells in cultures of PBMC stimulated with blood-stage Plasmodium falciparum malarial Ag. Flow cytometry revealed that maximal gamma delta T cell prolife
Publikováno v:
The Journal of Immunology. 157:1620-1624
We determined the requirement for selected lymphocyte subsets and cytokines in the pathogenesis of experimental murine cerebral malaria (CM) by using gene-targeted knockout and mAb-suppressed mice. Plasmodium berghei ANKA infection induced CM in A 0/
Autor:
Joan Batchelder, H C van der Heyde, W L Chang, William P. Weidanz, M. Merle Elloso, Barbara J. Pepper
Publikováno v:
Journal of Leukocyte Biology. 60:221-229
Mice rendered B cell-deficient either by chronic anti-mu treatment initiated at birth or by gene knockout (JHD and mu-MT mice) suppressed acute Plasmodium chabaudi infections with a time course similar to intact control mice. Moreover, both kinds of
Autor:
Andrés Vázquez-Torres, Edward Balish, H C van der Heyde, R D Wagner, Jessica Jones-Carson, Thomas F. Warner
Publikováno v:
Nature Medicine. 1:552-557
Despite the prevalence of gamma delta T cells in mucosae that are typically colonized by Candida albicans, little is known of the possible role of these cells in resistance to candidiasis. A sharp increase in the number of gamma delta T cells and mac
Publikováno v:
The Journal of Immunology. 154:3985-3990
To determine whether gamma delta T cells are essential for the resolution of acute Plasmodium chabaudi adami (P. c. adami) malaria, we depleted gamma delta T cells from C57BL/6 mice with hamster monoclonal anti-TCR gamma delta Ab treatment. During th
Publikováno v:
The Journal of Immunology. 153:1187-1194
As assessed by flow cytometry, human gamma delta T cells were shown here to inhibit replication of blood-stage Plasmodium falciparum in vitro in a dose-dependent fashion; no other leukocyte population tested was suppressive. Replication of intraeryth
Publikováno v:
The Journal of Immunology. 152:4557-4562
Because the role of cell-mediated immunity (CMI) in the resolution of blood-stage malaria remains unclear, we examined the question of whether mice completely lacking Ab-mediated immunity (AMI) but possessing some CMI can resolve experimental malaria
Publikováno v:
The Journal of Immunology. 151:6311-6317
The previously observed expansion of the splenic gamma delta T cell subset was examined during the course of murine malaria to determine whether CD4+ T cells are required. Flow cytometric analysis during the course of Plasmodium chabaudi adami malari
γδ T-Cell Function in Pathogenesis of Cerebral Malaria in Mice Infected with Plasmodium berghei ANKA
Publikováno v:
Infection and Immunity. 67:446-448
Mice depleted of γδ T cells by monoclonal antibody treatment and infected with Plasmodium berghei ANKA did not develop cerebral malaria (CM). In striking contrast, δ 0/0 mice infected with P. berghei developed CM despite their γδ T-cell deficien