Výsledky vyhledávání

Hormonal Profile after Insulin-Induced Hypoglycemia in Chronic Calcific Pancreatitis: Pancreatic, Pituitary and Adrenal Responses

Autor: Harry J. Hirsch, Irving M. Spitz, Segal I, R. Shires, Barry I Joffe, H C Seftel

Publikováno v: Hormone and Metabolic Research. 16:134-137

The present investigation defined the pattern of pancreatic, pituitary and adrenal responses after insulin-induced hypoglycemia in chronic calcific pancreatitis (CCP) related to alcohol abuse, and assessed the role of some of these hormones in the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45478d549778e5360f5e135f30218b8
https://doi.org/10.1055/s-2007-1014917

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Diabetes mellitus in the black communities of Southern Africa

Autor: H. C. Seftel, B. I. Joffe

Publikováno v: Journal of Internal Medicine. 235:137-142

This review, written in the format of a series of answers to topical questions about DM. will outline the current position regarding prevalence amongst black Southern Africans. highlight its pathogenesis, compare this to the situation found in black

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb666fd84e7b099dd1a1ee46c684b09
https://doi.org/10.1111/j.1365-2796.1994.tb01047.x

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Characterization of six patients who are double heterozygotes for familial hypercholesterolemia and familial defective apo B-100

Autor: H C Seftel, G Pilcher, David C. Rubinsztein, F J Raal, D R van der Westhuyzen, G. A. Coetzee

Publikováno v: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 13:1076-1081

Familial defective apolipoprotein B-100 (FDB) and familial hypercholesterolemia (FH) are the common causes of monogenic primary hypercholesterolemia. An individual of mixed English and Afrikaner descent with both FDB and the FH Afrikaner-1 low-densit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e54c1ee2da99cf58201a6f8188867a
https://doi.org/10.1161/01.atv.13.7.1076

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Identification and properties of the proline664-leucine mutant LDL receptor in South Africans of Indian origin

Autor: E Leitersdorf, A.D. Marais, D R van der Westhuyzen, H C Seftel, David C. Rubinsztein, G. A. Coetzee

Publikováno v: Journal of Lipid Research, Vol 33, Iss 11, Pp 1647-1655 (1992)
Europe PubMed Central

The incidence of familial hypercholesterolemia (FH) is high among South African Indians. The proline664-leucine low density lipoprotein (LDL)-receptor mutation was detected in four apparently unrelated Indian FH families in South Africa. This mutatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878c79ed1fd36d75648823b26605b022
http://www.sciencedirect.com/science/article/pii/S0022227520413872

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Relationship Between Plasma Insulin and Blood Pressure in South African Black Women in Johannesburg

Autor: Jefrey R Wing, Frederick J. Raal, Vanessa R. Panz, Barry I Joffe, H C Seftel

Publikováno v: Diabetes Care. 15:556-558

Objectives To examine the relationship between fasting plasma insulin and blood pressure (BP) in 40 urbanized normotensive South African black women aged 24–60 yr, and to assess the effects of body mass index (BMI) and fasting plasma glucose on BP.

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https://doi.org/10.2337/diacare.15.4.556

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Comprehensive management of non-insulin-dependent diabetes mellitus. A diabetes clinic revisited

Autor: F J, Raal, D R, Taylor, B I, Joffe, H C, Seftel

Publikováno v: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 86

To 'revisit' the Johannesburg Hospital diabetes clinic to ascertain whether the established risk factors for CAD were being identified and appropriately managed.Body mass indices (BMI), fasting lipograms and glycated haemoglobin (HBA) estimations wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30f16d9e44410debd516872cf8992da1
https://pubmed.ncbi.nlm.nih.gov/9180771

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SSCP analysis of the tyrosine kinase domain of the insulin receptor gene: polymorphisms detected in South African black and white subjects

Autor: Barry I Joffe, Mary-Anne Kedda, H C Seftel, Vanessa R. Panz, Paul Ruff

Publikováno v: Human genetics. 97(4)

The frequency of DNA polymorphisms in the tyrosine kinase domain (exons 17-21) of the insulin receptor gene was assessed in 30 black and 30 white South Africans, using single-stranded conformation polymorphism and direct sequencing analysis. A compar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8e912ced5b7d736baf0c450128b9bf
https://pubmed.ncbi.nlm.nih.gov/8834239

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MED-PED: An Integrated Genetic Strategy for Preventing Early Deaths

Publikováno v: Genetic Approaches to Noncommunicable Diseases ISBN: 9783642646621

New opportunities are emerging for preventing the consequences of serious diseases because of the discovery of causal mutations in specific gene loci. MED PED is an international collaboration to Make Early Diagnoses and Prevent Early Deaths in MEDic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b3951ffd3ab5bd2df0e23f541cdebce
https://doi.org/10.1007/978-3-642-61028-8_5

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Renal and neuromuscular respiratory failure--is this a syndrome associated with cantharidin poisoning?

Autor: M, Zouvanis, C, Feldman, C, Smith, D A, Promnitz, S, James, H C, Seftel

Publikováno v: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 84

To describe the clinical and laboratory features of patients with renal and neuromuscular respiratory failure due to suspected cantharidin poisoning.Retrospective record review of cases with neuromuscular respiratory failure.Intensive Care Unit (ICU)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::797905bed07725c1956fd798e0b1493c
https://pubmed.ncbi.nlm.nih.gov/8914545

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