Výsledky vyhledávání - "H C, Schoemaker"

The effect of motilin on the rectum in healthy volunteers

Autor: M. F. Oppenhuizen-Duinker, H. C. Schoemaker, R. Jones, Ad A.M. Masclee, A. D. Van Haarst, Ingrid M C Kamerling, J. Burggraaf, Adam F. Cohen, Hartmut Heinzerling, Izak Biemond

Publikováno v: British Journal of Clinical Pharmacology. 55:538-543

Aims The role of motilin in the regulation of upper gastrointestinal (GI) motility is well defined. However, little is known about the effects on the distal GI tract. To investigate the effect of exogenous motilin on rectal function, barostat measure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce018f809a5b86cb493d7d28ea2d8b4e
https://doi.org/10.1046/j.1365-2125.2003.01812.x

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Autor: Adam F. Cohen, Ad A.M. Masclee, H. C. Schoemaker, Ingrid M. C. Kamerling, Richard Jones, A. D. Van Haarst, Izak Biemond, J. Burggraaf

Publikováno v: Alimentary Pharmacology & Therapeutics. 16:129-135

Aim: To assess non-invasively the dose–response relations for the effects of exogenous motilin on antrum contraction frequency, gall-bladder volume and gastric myoelectrical activity. Methods: In a double-blind, randomized, placebo-controlled, five

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dc7e9d8102bce91d8c35c9ef9b45cfb
https://doi.org/10.1046/j.1365-2036.2002.01142.x

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The gastrointestinal passage and release of beclomethasone dipropionate from oral delivery systems in ileostomy volunteers

Autor: J. Burggraaf, H. C. Schoemaker, A. D. Van Haarst, Adam F. Cohen, W. J. J. Krauwinkel, P. Fockens

Publikováno v: British Journal of Clinical Pharmacology. 46:207-214

Aims To study the delivery of 15 mg beclomethasone 17,21-dipropionate (BDP) to the distal part of the small bowel for three oral sustained-release formulations (I-III) and a reference capsule in volunteer ileostomists, and to compare these findings w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5188d8f15bc1aca87e984aee67e7ef91
https://doi.org/10.1046/j.1365-2125.1998.00782.x

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Low-dose infusion of recombinant tissue-type plasminogen activator in healthy volunteers to investigate the biodistribution of t-PA in the early phase of infusion

Autor: Cornelis Kluft, Adam F. Cohen, Linda G. M. Huisman, J. M. T. Van Griensven, H. C. Schoemaker

Publikováno v: Fibrinolysis and Proteolysis. 11:21-27

Summary Earlier observations suggested deviations from expected pharmacokinetics of recombinant tissue-type plasminogen activator (rt-PA) in the early phase of a low-dose infusion. A study with two low-dose intravenous infusions of rt-PA was performe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5140eb7f033b107cf94971a432bbb20
https://doi.org/10.1016/s0268-9499(97)80005-7

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The effects of clonazepam and vigabatrin in hyperekplexia

Autor: P.J Edelbroek, J.G. van Dijk, H. C. Schoemaker, Raymund A.C. Roos, Marina A. J. Tijssen, Adam F. Cohen

Publikováno v: Journal of the neurological sciences, 149(1), 63-67. Elsevier

Hyperekplexia is an autosomal dominant disorder caused by a point mutation in the alpha1 subunit of the glycine receptor, characterized by excessive startle responses followed by temporary generalized stiffness. Clonazepam, effective in open case stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14a392ac9c84f693c8b6a15614b4f03
https://doi.org/10.1016/s0022-510x(97)05378-1

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Effects of intravenous temazepam. II. A study of the long-term reproducibility of pharmacokinetics, pharmacodynamics, and concentration-effect parameters

Autor: H. C. Schoemaker, Alfred L van Steveninck, Adam F. Cohen, Jan den Hartigh, Douwe D. Breimer, M. S. M. Pieters

Publikováno v: Europe PubMed Central

To evaluate the long-term reproducibility of pharmacokinetic, pharmacodynamic, and concentration-effect parameters after intravenous administration of temazepam.Nine healthy volunteers were studied. Temazepam, 0.4 mg/kg, was infused intravenously for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233effdf17a6900260dd23b792ad7519
https://doi.org/10.1038/clpt.1994.68

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Abstracts of papers clinical pharmacological meeting

Autor: M. M. Klauw, B. H. Ch. Stricker, J. P. Ottervanger, F. G. A. Meché, J. M. T. Griensven, H. H. P. J. Lemkes, J. M. Kroon, H. C. Schoemaker, A. F. Cohen, J. H. M. Schellens, W. Loos, B. Acker, M. Boer-Dennert, A. S. T. Planting, M. E. L. Burg, G. Stoter, R. Krediet, J. Verweij, E. E. Blaak, M. A. Baak, G. J. Kemerink, M. T. W. Pakbiers, G. A. K. Heidendal, W. H. M. Saris, S. Bouckaert, L. Vakaet, M. Dhont, J. P. Remon, S. A. J. Broek, P. A. Graeff, W. H. Gilst, D. J. Veldhuisen, H. L. Hillige, H. Wesseling, K. I. Lie, C. A. Gaillard, P. N. Es, P. W. Leeuw, L. M. A. B. Bortel, M. J. F. Kool, F. A. T. Lustermans, J. G. S. Breed, A. P. G. Hoeks, H. A. J. Struijker Boudier, R. P. Pickkers, P. Smits, H. Baadenhuysen, A. Laar, Th. Thien, M. M. Elseviers, M. E. Broe, A. J. A. M. Ven, P. P. Koopmans, W. H. M. Peters, T. B. Vree, J. W. M. Meer, E. Snoeck, A. Peer, M. Sack, M. Horton, G. Mannens, R. Woestenborghs, J. Heykants, R. Meibach, T. B. Witsen, H. A. Valkenburg, R. H. Stichele, B. Potter, P. Vyncke, M. G. Bogaert, J. Burggraaf, H. Wollersheim, J. Aalen, R. G. Schoemaker, X. Y. Du, W. A. Bax, E. Bos, P. R. Saxena, G. A. Rongen, P. N. M. Heiningen, H. R. Schwietert, J. M. Kortboyer, F. A. E. Sollie, C. Piraube, P. Desché, J. H. G. Jonkman, W. L. Blok, I. C. Gyssens, Y. A. Hekster, P. A. F. Jansen, R. C. Sival, J. F. Nieuwkerk, B. Klaverwiiden, E. A. Bruijn, O. Driessen

Publikováno v: Pharmacy World & Science. 15:1-7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef2aae6a441771cb628d57e3209c1802
https://doi.org/10.1007/bf01876624

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Pharmacodynamic interactions of diazepam and intravenous alcohol at pseudo steady state

Autor: J. M. Kroon, Ronald Gieschke, Douwe D. Breimer, M. S. M. Pieters, H. C. Schoemaker, Adam F. Cohen, A. L. Van Steveninck

Publikováno v: Psychopharmacology. 110:471-478

Pharmacodynamic interactions of low doses of diazepam and alcohol were investigated in a double blind, randomised, 2 x 2 factorial, cross-over study in eight healthy volunteers. Alcohol or glucose 5% were administered intravenously at rates calculate

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https://doi.org/10.1007/bf02244655

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Autor: A. L. Van Steveninck, M. S. M. Pieters, Adam F. Cohen, H. C. Schoemaker, D. D. Breimer

Publikováno v: British Journal of Clinical Pharmacology. 35:114-120

1. The effects of metoprolol-Oros 14/190 once daily, propranolol 80 mg twice daily and temazepam 10 mg once daily on central nervous system (CNS) related performance and haemodynamic variables were evaluated in a double-blind, randomized, placebo con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32c79b0305a7d7723d04f72418c803f
https://doi.org/10.1111/j.1365-2125.1993.tb05676.x

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