Zobrazeno 1 - 10
of 56
pro vyhledávání: '"H C, Charles"'
Autor:
M.-P. Hellio Le Graverand, O. Nemirovskyi, David J. Hunter, B. Wyman, H. C. Charles, Robert J. Buck, Felix Eckstein, T. Sunyer, Virginia B. Kraus
Publikováno v:
Annals of the Rheumatic Diseases. 70:1223-1230
Objective To examine the relationship of baseline clinical, radiographic, molecular and MRI measures with structural progression (subregional MRI-based femorotibial cartilage loss) in knee osteoarthritis (OA). Methods Single knees of 75 female partic
Publikováno v:
Journal of Orthopaedic Research. 28:1149-1154
Obesity, as a primary risk factor for osteoarthritis (OA), has been shown to alter joint loading, but may also result in metabolic changes characterized by chronic, low-level inflammation due to increased circulating levels of adipose-derived cytokin
Autor:
Thomas M. Link, S. Majumdar, Muriel Piperno, Virginia B. Kraus, Kenneth D. Brandt, Pottumarthi V. Prasad, Eric Vignon, Christopher G. Jackson, A. Vaz, David J. Hunter, M.-P. Hellio Le Graverand, B. Wyman, Martin Hudelmaier, H. C. Charles, Robert J. Buck, Thomas J. Schnitzer, S.A. Mazzuca, Felix Eckstein, Wolfgang Wirth
Publikováno v:
Osteoarthritis and Cartilage. 17(9):1177-1185
Summary Objective To identify subregional differences in femorotibial cartilage morphology between healthy controls and women with different grades of radiographic knee osteoarthritis (OA). Design 158 women aged ≥40 years were studied. Weight-beari
Autor:
F, Eckstein, R J, Buck, D, Burstein, H C, Charles, J, Crim, M, Hudelmaier, D J, Hunter, G, Hutchins, C, Jackson, V Byers, Kraus, N E, Lane, T M, Link, L S, Majumdar, S, Mazzuca, P V, Prasad, T J, Schnitzer, M S, Taljanovic, A, Vaz, B, Wyman, M-P Hellio, Le Graverand, Kenneth, Brandt
Publikováno v:
Annals of the Rheumatic Diseases. 67:1683-1688
Quantitative MRI (qMRI) of cartilage morphology is a promising tool for disease-modifying osteoarthritis drug (DMOAD) development. Recent studies at single sites have indicated that measurements at 3.0 Tesla (T) are more reproducible (precise) than t
Publikováno v:
Acta Neurologica Scandinavica. 102:20-26
This paper reviews published post-mortem brain and in-vivo proton magnetic resonance spectroscopy (1H-MRS) studies in Alzheimer's disease (AD) and focuses on the emerging role of N-acetylaspartate (NAA) as a prognostic marker of neuronal function. Po
Autor:
J. Sylvester, Suman Vidyarthi, K. R R Krishnan, P.M. Doraiswamy, Daniel P. Barboriak, H. C. Charles
Publikováno v:
Neurology. 54:2150-2153
Article abstract Hippocampal sulcal cavities are usually considered incidental findings on brain MRI. In a group of 92 elderly volunteers, the authors graded the number and size of hippocampal sulcal cavities with brain MRI to obtain a cavity score.
Autor:
H P McAdams, P Bogonad, J M Majure, Lane F. Donnelly, James R. MacFall, H C Charles, Donald P. Frush, Jean S. Smith, Carl E. Ravin
Publikováno v:
Radiology. 212:885-889
Four patients with cystic fibrosis (CF) were examined with combined hyperpolarized helium 3-enhanced and conventional proton magnetic resonance (MR) imaging. After inhalation of the polarized 3He gas, single breath-hold, gradient-echo images (resonan
Autor:
J. L. K. Van Hove, F. Lazeyras, Linda Gray, H. C. Charles, Jaak Jaeken, T. Bottiglieri, Stephen G. Kahler, Steven H. Zeisel, K. Hyland
Publikováno v:
Journal of Inherited Metabolic Disease. 21:799-811
Non-ketotic hyperglycinaemia (NKH) is a rare, severe brain disease caused by deficient glycine cleavage enzyme complex activity resulting in elevated glycine concentrations. Recent experience suggests that factors in addition to glycine kinetics are
Autor:
Christopher J. Erickson, Carl E. Ravin, H C Charles, Bastiaan Driehuys, Gordon D. Cates, G. A. Johnson, H. Middleton, J. C. Swartz, James R. MacFall, William Happer, Brian Saam, R.D. Black
Publikováno v:
Radiology. 200:553-558
Two healthy volunteers who had inhaled approximately 0.75 L of laser-polarized helium-3 gas underwent magnetic resonance imaging at 1.5 T with fast gradient-echo pulse sequences and small flip angles ( < 10 degrees). Thick-section (20 mm) coronal ima
Publikováno v:
Magnetic Resonance in Medicine. 35:606-610
The application of proton (1H) magnetic resonance spectroscopic imaging (MRSI) allows for noninvasive, localized analyses of brain biochemistry; however, minimal work has been devoted to the evaluation of 1H MRSI reproducibility. This study examined