Zobrazeno 1 - 10
of 129
pro vyhledávání: '"H Brent Clark"'
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2023)
We report a rare case of biopsy-proven isolated immunoglobulin G4 (IgG4)-related hypophysitis and Rathke’s cleft cyst (RCC) presenting as panhypopituitarism. A 54-year-old Caucasian female presented with symptoms of slurred speech, altered mental s
Externí odkaz:
https://doaj.org/article/661e9953485a4ed486460ae28fa90af5
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2018)
IgG4-related hypophysitis is an important diagnostic consideration in patients with a pituitary mass or pituitary dysfunction and can initially present with headaches, visual field deficits and/or endocrine dysfunction. Isolated IgG4-related pituitar
Externí odkaz:
https://doaj.org/article/e90cdde8a4044b109c2e3814600296b4
Autor:
H. Brent Clark
Publikováno v:
Brain Sciences, Vol 12, Iss 2, p 257 (2022)
Autoimmune-mediated ataxia has been associated with paraneoplastic disease, gluten enteropathy, Hashimoto thyroiditis as well as autoimmune disorders without a known associated disease. There have been relatively few reports describing the neuropatho
Externí odkaz:
https://doaj.org/article/c0e3ca314cd3471695d3ada29e2aebb4
Publikováno v:
Neurobiology of Disease, Vol 116, Iss , Pp 69-77 (2018)
Spinocerebellar ataxia type 1 (SCA1) is a fatal inherited neurodegenerative disease. In this study, we demonstrate the label-free optical imaging methodology that can detect, with a high degree of sensitivity, discrete areas of degeneration in the ce
Externí odkaz:
https://doaj.org/article/f00fe5d3852a404d93666da1c25c0d49
Autor:
Brent Berry, Stephanie Joppa, Edward Labin, Vikram Puram, Kaci McCleary, H. Brent Clark, Flavia Nelson
Publikováno v:
Life, Vol 11, Iss 11, p 1120 (2021)
Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the
Externí odkaz:
https://doaj.org/article/0ef4edbbd52145b6aa1f53a3102a268b
Autor:
Gülin Öz, Emily Kittelson, Döne Demirgöz, Orion Rainwater, Lynn E. Eberly, Harry T. Orr, H. Brent Clark
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 158-166 (2015)
Suppression of transgene expression in a conditional transgenic mouse model of spinocerebellar ataxia 1 (SCA1) reverses the Purkinje cell pathology and motor dysfunction that are hallmarks of SCA1. We previously showed that cerebellar neurochemical l
Externí odkaz:
https://doaj.org/article/d0ac534b1da847ebb0c9958edc5b43a8
Autor:
Ghaidan A. Shamsan, Chao J. Liu, Brooke C. Braman, Susan K. Rathe, Aaron L. Sarver, Nima Ghaderi, Mariah M. McMahon, Rebecca L. Klank, Barbara R. Tschida, S. Joey McFarren, Pamela C. Rosato, David Masopust, Jann N. Sarkaria, H. Brent Clark, Steven S. Rosenfeld, David A. Largaespada, David J. Odde
SUMMARYGlioblastoma remains a deadly cancer driven by invasion of tumor cells into the brain. Transcriptomic analyses have revealed distinct molecular subtypes, but mechanistic differences that explain clinical differences are not clear. Here, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d23ad164c074cfa8d8ecf88b97687e16
https://doi.org/10.1101/2022.06.26.497270
https://doi.org/10.1101/2022.06.26.497270
Autor:
H. Brent Clark, Rajagopal N. Aravalli, John W. Osborn, Parker O’Brien, Dalong Liu, Hasan Aldiabat, Dusty Van Helden, M. Gerard O'Sullivan, Emad S. Ebbini, Alexandru Flaviu Tăbăran
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Carotid bodies (CBs) are chemoreceptors that monitor and register changes in the blood, including the levels of oxygen, carbon dioxide, and pH, and regulate breathing. Enhanced activity of CBs was shown to correlate with a significant elevation in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171c439309b69f95cddfb70c7db2a341
http://link.springer.com/article/10.1038/s41598-020-66209-0
http://link.springer.com/article/10.1038/s41598-020-66209-0
Autor:
Mathieu Marella, Xiang Yao, Vinicius Carreira, Marta F. Bustamante, H. Brent Clark, Carolyn C. Jackson, Enrique Zudaire, Jordan M. Schecter, Tynisha D. Glover, Jacintha Shenton, Ingrid Cornax
Publikováno v:
J Histochem Cytochem
B-cell maturation antigen (BCMA) is a target for the treatment of multiple myeloma with cytolytic therapies, such as chimeric antigen receptor T-cells or T-cell redirecting antibodies. To better understand the potential for “on-target/off-tumor”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2aab657a4b23cf6ef58b8827699f46a
https://europepmc.org/articles/PMC8971684/
https://europepmc.org/articles/PMC8971684/
Autor:
Flavia Nelson, Brent M. Berry, Edward Labin, Stephanie Joppa, Kaci McCleary, Vikram Puram, H. Brent Clark
Publikováno v:
Life, Vol 11, Iss 1120, p 1120 (2021)
Life
Life
Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cc4c365214480f5fe8f474bbe383d4
https://www.mdpi.com/2075-1729/11/11/1120
https://www.mdpi.com/2075-1729/11/11/1120