Zobrazeno 1 - 10
of 330
pro vyhledávání: '"H Bluethmann"'
Autor:
ZhiQiang Liu, Marion Bohatschek, Christian U.A. Kloss, M. Labow, Gennadij Raivich, H. Bluethmann
Publikováno v:
Experimental Neurology. 178:186-193
Neural injury is known to trigger inflammatory changes, including the synthesis of proinflammatory cytokines such as interleukin-1-beta (IL1beta), tumor necrosis factor-alpha (TNFalpha), and interferon-gamma (IFNgamma) [G. Raivich, L. L. Jones, C. U.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a56cd4c04e2bdbad7e8ceb74447ce1
https://doi.org/10.1006/exnr.2002.8024
https://doi.org/10.1006/exnr.2002.8024
Autor:
C K Edwards, T Zhou, J Zhang, T J Baker, M De, R E Long, D R Borcherding, T L Bowlin, H Bluethmann, J D Mountz
Publikováno v:
The Journal of Immunology. 157:1758-1772
We have used fas-defective MRL-lpr/lpr mice to study the effects of the staphylococcal enterotoxin superantigens on the development of autoimmune, inflammatory joint disease in animals that are susceptible to the development of rheumatoid arthritis-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e594e15baf2b08deddb486a9da33e05d
https://doi.org/10.4049/jimmunol.157.4.1758
https://doi.org/10.4049/jimmunol.157.4.1758
Publikováno v:
The Journal of Immunology. 156:2661-2665
Fas and TNF receptor I (TNF-RI) share homology at their cytoplasmic death domain and belong to the same gene family, but utilize different pathways to signal activation-induced cell death. To determine the combined effects of defective TNF-RI and Fas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b8dd3b8f0903366c0b0258065085bf
https://doi.org/10.4049/jimmunol.156.8.2661
https://doi.org/10.4049/jimmunol.156.8.2661
Publikováno v:
The Journal of Immunology. 155:4829-4837
MRL-lpr/lpr mice are defective in the fas Ag/APO-1 apoptosis gene (CD95). Using the hepatotoxin D-galactosamine (D-GalNH2), we demonstrate that MRL-lpr/lpr mice have an increased susceptibility to staphylococcal enterotoxin B (SEB)-induced lethal sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368c594320946e1a4987987ef991bfcd
https://doi.org/10.4049/jimmunol.155.10.4829
https://doi.org/10.4049/jimmunol.155.10.4829
Autor:
Naofumi Mukaida, Yi Zhang, Akihisa Harada, H. Bluethmann, Koji Matsushima, Jian-bin Wang, Nakao S
Publikováno v:
Blood. 86:2930-2937
Murine bone marrow cells with lineage phenotypes (Lin)-Sca-1+c-kit+ and Lin-Sca-1-c-kit+ cells represent primitive hematopoietic stem cells (HSCs) and committed hematopoietic progenitor cells, respectively. The number of Lin-Sca-1+c-kit+ HSCs in bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378b789f4b7c851b7139b4249c7cdd05
https://doi.org/10.1182/blood.v86.8.2930.2930
https://doi.org/10.1182/blood.v86.8.2930.2930
Publikováno v:
The Journal of Immunology. 153:5274-5284
The role of the two TNF receptor types, TNF-R55 and TNF-R75, was studied on mouse fibroblasts, taking advantage of TNF-R55-deficient mice generated by gene targeting (Tnfr1 degree-mice), and selectivity of human TNF-alpha for mouse TNF-R55. Radioliga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a71f3a5ed921da28532f6dc10cdadc89
https://doi.org/10.4049/jimmunol.153.11.5274
https://doi.org/10.4049/jimmunol.153.11.5274
Publikováno v:
The EMBO Journal. 12:2329-2336
Immunoglobulins (Ig) secreted from a plasma cell contain either kappa or lambda light chains, but not both. This phenomenon is termed isotypic kappa-lambda exclusion. While kappa-producing cells have their lambda chain genes in germline configuration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483be65a1933099f5d9185016e82b0b4
https://doi.org/10.1002/j.1460-2075.1993.tb05887.x
https://doi.org/10.1002/j.1460-2075.1993.tb05887.x
Publikováno v:
The Journal of Immunology. 150:3651-3667
Abnormal development of T cells in the thymus is thought to be related to autoimmune disease and the expansion of the unusual CD4-CD8-B220+ peripheral T cel subset that results in lymphadenopathy in MRL-lpr/lpr mice. Although we and others have previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e29d3dcde7db56e3ba28aa3338d35205
https://doi.org/10.4049/jimmunol.150.8.3651
https://doi.org/10.4049/jimmunol.150.8.3651
Publikováno v:
The Journal of Immunology. 147:466-474
Development of a C57BL/6-+/+ TCR transgenic mouse containing the rearranged TCR alpha- and beta-chain specific for the Db + HY male Ag results in production of a nearly monoclonal population of early thymocytes expressing the Db + HY reactive TCR. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0575d8a7272fdfb6447e64aa1e1d2235
https://doi.org/10.4049/jimmunol.147.2.466
https://doi.org/10.4049/jimmunol.147.2.466
Autor:
F. Mueller-Spahn, F. Meier, Anne Eckert, J. Goetz, Rhein, L. Ozmen, C. Czech, Egemen Savaskan, H. Bluethmann, G. Baysang
Publikováno v:
Pharmacopsychiatry. 40
Alzheimer's disease is characterized by neuropathological hallmarks of extracellular amyloid plaques and intracellular neurofibrillary tangles in the brain of patients. Amyloid plaques are composed of the amyloid-beta (Aβ) protein, derived from its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2a06b4415d069e018e08064e101dfa
https://doi.org/10.1055/s-2007-991813
https://doi.org/10.1055/s-2007-991813