Zobrazeno 1 - 10
of 75
pro vyhledávání: '"H Benjamin Peng"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90187 (2014)
In a majority of patients with myasthenia gravis (MG), anti-acetylcholine receptor (AChR) antibodies target postsynaptic AChR clusters and thus compromise the membrane integrity of neuromuscular junctions (NMJs) and lead to muscle weakness. Antibody-
Externí odkaz:
https://doaj.org/article/f746e180ff6a43deaada02e68743293a
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44759 (2012)
BACKGROUND: The assembly of the vertebrate neuromuscular junction (NMJ) is initiated when nerve and muscle first contact each other by filopodial processes which are thought to enable close interactions between the synaptic partners and facilitate sy
Externí odkaz:
https://doaj.org/article/a37f8f49d5574a59960b7c2ba2cce98b
Autor:
Hailong Luke Zhang, H Benjamin Peng
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26805 (2011)
BACKGROUND: The formation of acetylcholine receptor (AChR) cluster is a key event during the development of the neuromuscular junction. It is induced through the activation of muscle-specific kinase (MuSK) by the heparan-sulfate proteoglycan agrin re
Externí odkaz:
https://doaj.org/article/d998bb5a5d6349b380bb6661636341e7
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8478 (2009)
BACKGROUND:Postsynaptic enrichment of acetylcholine receptors (AChRs) at the vertebrate neuromuscular junction (NMJ) depends on the activation of the muscle receptor tyrosine MuSK by neural agrin. Agrin-stimulation of MuSK is known to initiate an int
Externí odkaz:
https://doaj.org/article/b2390dc571f7466d9a3ffa02eb98aa95
Publikováno v:
Molecular Biology of the Cell
We have carried out a comparative study of the lateral motion of ganglioside GM1, which is a glycosphingolipid residing on the outer leaflet of the plasma membrane, and acetylcholine receptor (AChR), which is a well-characterized ion channel. Both th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b98f93701a8f56d7a19706d9721b443
https://doi.org/10.1091/mbc.e19-08-0473
https://doi.org/10.1091/mbc.e19-08-0473
Autor:
H. Benjamin Peng, Yang Zhao
Publikováno v:
Neuroscience letters. 733
The formation of acetylcholine receptor (AChR) clusters at the postsynaptic muscle membrane in response to motor innervation is a key event in the development of the neuromuscular junction. The synaptic AChR clustering process is initiated by motor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c98cd71192885f3f73d3e9aed5df1d
https://pubmed.ncbi.nlm.nih.gov/32428606
https://pubmed.ncbi.nlm.nih.gov/32428606
Autor:
H. Benjamin Peng, Nicolas Arbez, Christopher A. Ross, Xin Sun, Shanshan Zhu, Arnulf H. Koeppen, Pan P. Li, Guangbin Xia, Dobrila D. Rudnicki, Tetsuo Ashizawa, Russell L. Margolis, Stefan M. Pulst, Sharan Paul
Publikováno v:
Annals of Neurology. 80:600-615
Objective Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease caused by a CAG repeat expansion in the gene ataxin-2 (ATXN2). ATXN2 intermediate-length CAG expansions were identified as a risk factor for amyotrophic lateral sclerosis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ad386ad23428f15a0067672d7ab0598
https://doi.org/10.1002/ana.24761
https://doi.org/10.1002/ana.24761
Publikováno v:
Molecular Biology of the Cell
The signaling by p120 catenin via its downstream effector RhoA is essential for filopodial growth and synaptic vesicle clustering along spinal axons and contributes to the formation of the neuromuscular junction.
At the developing neuromuscular
At the developing neuromuscular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e80116f0fe75b1d6ee5d345943e1cba
https://doi.org/10.1091/mbc.e12-01-0004
https://doi.org/10.1091/mbc.e12-01-0004
Publikováno v:
Pflugers Archiv
Nicotinic acetylcholine receptors (nAChRs) are heteropentameric ligand-gated ion channels that mediate excitatory neurotransmission at the neuromuscular junction (NMJ) and other peripheral and central synapses. At the NMJ, acetylcholine receptors (AC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222b379059c311f6081b88ffe19fb593
https://doi.org/10.1007/s00424-012-1132-9
https://doi.org/10.1007/s00424-012-1132-9
Autor:
Pan P. Li, H. Benjamin Peng
Publikováno v:
Molecular Biology of the Cell
Axonal growth and synaptogenesis are sequential events of neuronal development. Phosphatase and tensin homologue (PTEN) is expressed in motor neurons, and its disruption leads to continued axonal extension, even upon muscle contact, leading to synapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6174b1a326a56630c9c643ce2aef1399
http://europepmc.org/articles/PMC3469524
http://europepmc.org/articles/PMC3469524