Zobrazeno 1 - 10
of 100
pro vyhledávání: '"H Bea, Kuiperij"'
Autor:
Lieke Jäkel, Anna M. De Kort, Arno Stellingwerf, Carla Hernández Utrilla, Iris Kersten, Marc Vervuurt, Yannick Vermeiren, Benno Küsters, Floris H. B. M. Schreuder, Catharina J. M. Klijn, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Cerebral amyloid angiopathy (CAA) is a highly prevalent and progressive pathology, involving amyloid-β (Aβ) deposition in the cerebral blood vessel walls. CAA is associated with an increased risk for intracerebral hemorrhages (ICH). Insigh
Externí odkaz:
https://doaj.org/article/89e88c86a4f344fb895e0337fee2ad6e
Autor:
Marc Vervuurt, H. Bea Kuiperij, Anna M. de Kort, Iris Kersten, Catharina J. M. Klijn, Floris H. B. M. Schreuder, Marcel M. Verbeek
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Sporadic cerebral amyloid angiopathy (sCAA) is a disease characterised by the progressive deposition of the amyloid beta (Aβ) in the cerebral vasculature, capable of causing a variety of symptoms, from (mild) cognitive impairment
Externí odkaz:
https://doaj.org/article/2b87a95110114374a209b54f84287a4f
Autor:
Anna M. De Kort, Kanishk Kaushik, H. Bea Kuiperij, Lieke Jäkel, Hao Li, Anil M. Tuladhar, Gisela M. Terwindt, Marieke J. H. Wermer, Jurgen A. H. R. Claassen, Catharina J. M. Klijn, Marcel M. Verbeek, Roy P. C. Kessels, Floris H. B. M. Schreuder
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Patients with sporadic cerebral amyloid angiopathy (sCAA) frequently report cognitive or neuropsychiatric symptoms. The aim of this study is to investigate whether in patients with sCAA, cognitive impairment and neuropsychiatric s
Externí odkaz:
https://doaj.org/article/03dc076b60694297b5a5dbf562df35bd
Autor:
Ingeborg Rasing, Sabine Voigt, Emma A. Koemans, Anna M. de Kort, Thijs W. van Harten, Ellis S. van Etten, Erik W. van Zwet, Erik Stoops, Cindy Francois, H. Bea Kuiperij, Catharina J.M. Klijn, Floris H.B.M. Schreuder, Louise van der Weerd, Matthias J.P. van Osch, Marianne A.A. van Walderveen, Marcel M. Verbeek, Gisela M. Terwindt, Marieke J.H. Wermer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Neurofilament light chain (NFL) is a biomarker for neuroaxonal damage and glial fibrillary acidic protein (GFAP) for reactive astrocytosis. Both processes occur in cerebral amyloid angiopathy (CAA), but studies investigating the p
Externí odkaz:
https://doaj.org/article/0774fef1756f448c8cf8ef7d6c1fd7b1
Autor:
Marc Vervuurt, Joseph M. Schrader, Anna M. de Kort, Iris Kersten, Hans J. C. T. Wessels, Catharina J. M. Klijn, Floris H. B. M. Schreuder, H. Bea Kuiperij, Jolein Gloerich, William E. Van Nostrand, Marcel M. Verbeek
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Cerebral amyloid angiopathy (CAA) is a form of small vessel disease characterised by the progressive deposition of amyloid β protein in the cerebral vasculature, inducing symptoms including cognitive impairment and cerebral haemorrhages. Du
Externí odkaz:
https://doaj.org/article/ae6635b300cb4d1ebf5188677a8dfa6a
Autor:
Ingeborg Rasing, Sabine Voigt, Emma A. Koemans, Anna M. de Kort, Thijs W. van Harten, Ellis S. van Etten, Erik W. van Zwet, Erik Stoops, Cindy Francois, H. Bea Kuiperij, Catharina J.M. Klijn, Floris H.B.M. Schreuder, Louise van der Weerd, Matthias J.P. van Osch, Marianne A.A. van Walderveen, Marcel M. Verbeek, Gisela M. Terwindt, Marieke J.H. Wermer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ba7cdf1e1de44ba692105223355907bf
Autor:
Anna M. de Kort, H. Bea Kuiperij, Lieke Jäkel, Iris Kersten, Ingeborg Rasing, Ellis S. van Etten, Sanneke van Rooden, Matthias J. P. van Osch, Marieke J. H. Wermer, Gisela M. Terwindt, Floris H. B. M. Schreuder, Catharina J. M. Klijn, Marcel M. Verbeek
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The diagnosis of probable cerebral amyloid angiopathy (CAA) is currently mostly based on characteristics of brain MRI. Blood biomarkers would be a cost-effective, easily accessible diagnostic method that may complement diagnosis b
Externí odkaz:
https://doaj.org/article/06e73ac1710342818de74131702d0e52
Autor:
Marc Vervuurt, Anna M. de Kort, Lieke Jäkel, Iris Kersten, Wilson F. Abdo, Floris H. B. M. Schreuder, Ingeborg Rasing, Gisela M. Terwindt, Marieke J. H. Wermer, Steven M. Greenberg, Catharina J. M. Klijn, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background To evaluate the potential of cerebrospinal fluid (CSF) levels of matrix metalloproteinases and tissue-type inhibitors (MMP; TIMP), and ratios of MMPs to TIMPs, to function as biomarkers for sporadic or hereditary cerebral amyloid
Externí odkaz:
https://doaj.org/article/3560505f068d49d390437f47507aa204
Autor:
Tainá M. Marques, Anouke van Rumund, Iris Kersten, Ilona B. Bruinsma, Hans J.C.T. Wessels, Jolein Gloerich, Charlotte Kaffa, Rianne A. J. Esselink, Bastiaan R. Bloem, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract The aim of our study was to investigate cerebrospinal fluid (CSF) tryptic peptide profiles as potential diagnostic biomarkers for the discrimination of parkinsonian disorders. CSF samples were collected from individuals with parkinsonism, wh
Externí odkaz:
https://doaj.org/article/20d7ff2906c34b81b81ceb6c702ca96f
Autor:
Paula Marazuela, Montse Solé, Anna Bonaterra-Pastra, Jesús Pizarro, Jessica Camacho, Elena Martínez-Sáez, H. Bea Kuiperij, Marcel M. Verbeek, Anna M. de Kort, Floris H. B. M. Schreuder, Catharina J. M. Klijn, Laura Castillo-Ribelles, Olalla Pancorbo, David Rodríguez-Luna, Francesc Pujadas, Pilar Delgado, Mar Hernández-Guillamon
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Brain accumulation of amyloid-beta (Aβ) is a crucial feature in Alzheimer´s disease (AD) and cerebral amyloid angiopathy (CAA), although the pathophysiological relationship between these diseases remains unclear. Numerous proteins are asso
Externí odkaz:
https://doaj.org/article/9993c0b683ed49239fdcfe80e48f6f7d