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Publikováno v:
Proceedings of the National Academy of Sciences. 88:8572-8576
Dihydrofolate reductase (DHFR; EC 1.5.1.3) is required in folate metabolism for the synthesis of purines, thymidine, and glycine. Although there have been several reports of induction of DHFR enzyme by methotrexate (MTX), a drug that competitively in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcb52538e3847902dcbb7dca8d6a3ea
https://doi.org/10.1073/pnas.88.19.8572
https://doi.org/10.1073/pnas.88.19.8572
