Zobrazeno 1 - 6
of 6
pro vyhledávání: '"H B, Kimmel"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(5)
The metabolic disposition of recainam, an antiarrhythmic drug, was compared in mice, rats, dogs, rhesus monkeys, and humans. Following oral administration of [14C]recainam-HCl, radioactivity was excreted predominantly in the urine of all species exce
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 10(6)
The concentrations of (R)-(-)- and (S)-(+)-oxazepam glucuronides in plasma and urine of several species have been measured. The relative amounts of these diastereoisomers vary among species. Thus, in the plasma and urine of rhesus monkeys the concent
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 2(1)
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 7(1)
Following single intragastric doses of d- and dl-[24C]norgestrel (Ng), rhesus monkeys excreted 29.5 +/- 2.0 (SE) and 52.6 +/- 5.4% of the administered radioactivity in urine. Fecal excretion accounted for 57.1 +/- 4.0 and 37.2 +/- 4.4%, respectively.
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 3(3)
Excretion data and urinary metabolite patterns of di-, d-, and l-norgestrel were obtained from women who received a single, oral 1.5-mg dose of 14C-labeled racemic norgestrel (Ng) or one of its enantiomers. The average percentage of administered radi
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 1(2)