Zobrazeno 1 - 10
of 48
pro vyhledávání: '"H Attaway"'
Autor:
Amy H. Attaway, Rocio Lopez, Nicole Welch, Annette Bellar, Umur Hatipoğlu, Joe Zein, Marielle PKJ Engelen, Srinivasan Dasarathy
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder with systemic consequences that can cause a muscle loss phenotype (MLP), which is characterized by the loss of muscle mass, muscle strength, or loss o
Externí odkaz:
https://doaj.org/article/592798e4bdff47c89243dd29b2f2ee27
Autor:
Amy H. Attaway, Annette Bellar, Nicole Welch, Jinendiran Sekar, Avinash Kumar, Saurabh Mishra, Umur Hatipoğlu, Merry‐Lynn McDonald, Elizabeth A. Regan, Jonathan D. Smith, George Washko, Raúl San José Estépar, Peter Bazeley, Joe Zein, Srinivasan Dasarathy
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 1083-1095 (2023)
Abstract Background Sarcopenia, or loss of skeletal muscle mass and decreased contractile strength, contributes to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). The severity of sarcopenia in COPD is variable,
Externí odkaz:
https://doaj.org/article/62aaf16a8ff94490b943c20b2a887b98
Autor:
Nicole Welch, Shashi Shekhar Singh, Ryan Musich, M. Shahid Mansuri, Annette Bellar, Saurabh Mishra, Aruna K. Chelluboyina, Jinendiran Sekar, Amy H. Attaway, Ling Li, Belinda Willard, Troy A. Hornberger, Srinivasan Dasarathy
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105325- (2022)
Summary: Skeletal muscle generation of ammonia, an endogenous cytotoxin, is increased during exercise. Perturbations in ammonia metabolism consistently occur in chronic diseases, and may blunt beneficial skeletal muscle molecular responses and protei
Externí odkaz:
https://doaj.org/article/58ed0697bcec441494f70e8cf21d93b0
Autor:
Avinash Kumar, Nicole Welch, Saurabh Mishra, Annette Bellar, Rafaella Nasciemento Silva, Ling Li, Shashi Shekhar Singh, Mary Sharkoff, Alexis Kerr, Aruna Kumar Chelluboyina, Jinendiran Sekar, Amy H. Attaway, Charles Hoppel, Belinda Willard, Gangarao Davuluri, Srinivasan Dasarathy
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
Ammonia is a cytotoxic metabolite with pleiotropic molecular and metabolic effects, including senescence induction. During dysregulated ammonia metabolism, which occurs in chronic diseases, skeletal muscle becomes a major organ for nonhepatocyte ammo
Externí odkaz:
https://doaj.org/article/0ebae34ec55e4a5d9fee0cbae28c8a7f
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252576 (2021)
Inhaled Corticosteroids (ICS) are commonly prescribed to patients with severe COPD and recurrent exacerbations. It is not known what impact ICS cause in terms of COVID-19 positivity or disease severity in COPD. This study examined 27,810 patients wit
Externí odkaz:
https://doaj.org/article/353511f74fbb48a68372cb24dd0bb28c
Autor:
Amy H. Attaway, Annette Bellar, Saurabh Mishra, Manikandan Karthikeyan, Jinendiran Sekar, Nicole Welch, Ryan Musich, Shashi Shekhar Singh, Avinash Kumar, Aishwarya Menon, Jasmine King, Ramon Langen, Justine Webster, Rachel G. Scheraga, Kristy Rochon, Jason Mears, Sathyamangla V. Naga Prasad, Maria Hatzoglou, Abhishek A. Chakraborty, Srinivasan Dasarathy
Publikováno v:
The Journal of Physiology, 601(3), 567-606. Wiley-Blackwell
KEY POINTS: Sarcopenia or skeletal muscle loss is one of the most frequent complications that contributes to mortality and morbidity in patients with chronic obstructive pulmonary disease (COPD). Unlike chronic hypoxia, prolonged intermittent hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed0bb6a32c36206eeedb85ac4dfdd00
https://doi.org/10.1113/JP283700
https://doi.org/10.1113/JP283700
Autor:
Saurabh Mishra, Nicole Welch, Manikandan Karthikeyan, Annette Bellar, Ryan Musich, Shashi Shekhar Singh, Dongmei Zhang, Jinendiran Sekar, Amy H. Attaway, Aruna Kumar Chelluboyina, Shuhui Wang Lorkowski, Sanjoy Roychowdhury, Ling Li, Belinda Willard, Jonathan D. Smith, Charles L. Hoppel, Vidula Vachharajani, Avinash Kumar, Srinivasan Dasarathy
Publikováno v:
Aging Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::facd9d55f010b78d202ae2d7d15b87cf
https://doi.org/10.1111/acel.13852
https://doi.org/10.1111/acel.13852
Publikováno v:
The Journal of Allergy and Clinical Immunology. in Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b3d43750e9e2dae710ecabf2297f6a
https://pubmed.ncbi.nlm.nih.gov/34718213
https://pubmed.ncbi.nlm.nih.gov/34718213
Publikováno v:
The Journal of Allergy and Clinical Immunology. in Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2453dff5be1aa4d8da0a0d59946a0ee
http://europepmc.org/articles/PMC8733312
http://europepmc.org/articles/PMC8733312
Autor:
Joe G. Zein, Ronald Strauss, Amy H. Attaway, Bo Hu, Alex Milinovich, Nesreen Jawhari, Soulaima S. Chamat, Victor E. Ortega
Publikováno v:
The Journal of Allergy and Clinical Immunology. in Practice
Background In addition to their proinflammatory effect, eosinophils have antiviral properties. Similarly, inhaled corticosteroids (ICS) were found to suppress coronavirus replication in vitro and were associated with improved outcomes in coronavirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf388c5f85a1d4d66cfce961e32acff
https://doi.org/10.1016/j.jaip.2021.12.034
https://doi.org/10.1016/j.jaip.2021.12.034