Zobrazeno 1 - 10
of 257
pro vyhledávání: '"H A Dissanayake"'
Autor:
N P Somasundaram, M Sumanatilleke, P Katulanda, C Garusinghe, S Abhayarathna, S Pathmanathan, S S C Gunathilake, C J Subhasinghe, A M Wijesinghe, M Arambewela, M D S A Dilrukshi, R U Vithiya, I Ranathunga, P S A Wijewickrama, H A Dissanayake, A M N L de Silva, N Yogendranathan, C A Jayasuriya,, W M U A Wijetunga, K K K Gamage
Publikováno v:
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, Vol 10, Iss 1, Pp 41-85 (2020)
No abstraxt available
Externí odkaz:
https://doaj.org/article/32433e220dde4d2a8e90d7f1cca83ecd
Autor:
Priyanga Ranasinghe, Chiranthi Liyanage, Nirmala Sirisena, Sandamini Liyanage, C. D. Nelanka Priyadarshani, D. P. Bhagya Hendalage, Vajira H. W. Dissanayake
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract Background Immunomodulators are important for management of autoimmune diseases and hematological malignancies. Significant inter-individual variation in drug response/reactions exists due to genetic polymorphisms. We describe frequency of i
Externí odkaz:
https://doaj.org/article/1837d50994954a04a2fec128baa4708e
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-7 (2024)
Abstract Background Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes and nemaline myopathy are two rare genetic conditions. We report the first case reported in world literature with coexistence of both these rare disorders.
Externí odkaz:
https://doaj.org/article/265d09f6f4e74b8996a9e257ccd61727
Autor:
Priyanga Ranasinghe, Nirmala Sirisena, Thuwaragesh Vishnukanthan, J. N. Ariadurai, Sathsarani Thilakarathne, C. D. Nelanka Priyadarshani, D. P. Bhagya Hendalage, Vajira H. W. Dissanayake
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Background Therapy with anti-cancer drugs remain the cornerstone of treating cancer. The effectiveness and safety of anti-cancer drugs vary significantly among individuals due to genetic factors influencing the drug response and metabolism.
Externí odkaz:
https://doaj.org/article/279e894234f64531bcf8cbe8cf81a772
Autor:
T. Nitharshan, T. Kumanan, N. D. Sirisena, G. Anandagoda, V. H. W. Dissanayake, S. Navaneethakrishnan, V. Sujanitha, V. Sutharhan, N. Mathangi
Publikováno v:
Sri Lanka Journal of Medicine, Vol 32, Iss 2, Pp 69-73 (2023)
A 27-year-old Sri Lankan man with Neurofibromatosis-1 (NF-1) [MIM:162200] who presented with vague abdominal pain associated with loss of weight and appetite for 1-year duration is described. He had multiple cutaneous neurofibromas, café-au-lait mac
Externí odkaz:
https://doaj.org/article/14238b048be944a3baca1d90e84e4b34
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-5 (2023)
Abstract Introduction Leber hereditary optic neuropathy is a genetic disease of mitochondrial inheritance characterized by bilateral irreversible vision loss, predominantly affecting males. We report the first genetically authenticated Sri Lankan cas
Externí odkaz:
https://doaj.org/article/2dd32faac22a491f9b359e89e43e4baa
Autor:
Madara S. B. Ralapanawe, Sugandika L. Gajaweera, Nishendra Karunaratne, Vajira H. W. Dissanayake, Malcolm J. Price, Pedro Melo, Arri Coomarasamy, Ioannis D. Gallos
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Recent studies suggest that chromosomal polymorphic variations are associated with infertility. A systematic review of chromosomal polymorphisms in assisted reproduction found an association with higher rates of miscarriage. Aim of this stud
Externí odkaz:
https://doaj.org/article/1f4adc6117c244239801da5ad8c41472
Autor:
M. C. P. Madurapperuma, R . B. A. T. Dulanjalie, T. M. H. M. Thennakoon, K. W. Gunawardena, W. W. L. A. Jayanaga, V. H. W. Dissanayake
Publikováno v:
Asian Journal of Internal Medicine, Vol 2, Iss 2 (2023)
Hereditary spherocytosis (HS) refers to a group of autosomal dominantly inherited heterogeneous hereditary haemolytic anaemias (HHA). Significant iron overload in HS is uncommon. Iron overload has been described as a complication of HS when there is
Externí odkaz:
https://doaj.org/article/4051818d96a0451e8d1738e3c9e8b2dd
Autor:
Ruwangi Dissanayake, Nayana Samarasinghe, Samantha Waidyanatha, Sajeewani Pathirana, Nilaksha Neththikumara, Vajira H. W. Dissanayake, Kalum Wetthasinghe, Lallindra Gooneratne, Pujitha Wickramasinghe
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Iron overload (IO) is a complication in transfusion dependent beta thalassaemia (TDT). Pathogenic variants in genes involving iron metabolism may confer increased risk of IO. The objective of this study was to determine the magnit
Externí odkaz:
https://doaj.org/article/22a2c7cc87bf4e4badf379c18be06a3b
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract The formation of the digits is a tightly regulated process. During embryogenesis, disturbance of genetic pathways in limb development could result in syndactyly; a common congenital malformation consisting of webbing in adjacent digits. Curr
Externí odkaz:
https://doaj.org/article/9f0ed4dc6e1d48d3b79264cf8404855c