A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations

Autor: Kelly F. Meijsen, Hugo R. de Jonge, Antje Ballauff, Anke H M van Vugt, Roderick H. J. Houwen, Manuel B Bryant, Thomas Müller, Sabine Middendorp, Tanja Restin, Marcel J. C. Bijvelds, Andreas R. Janecke, Bart G. P. Koot

Publikováno v: Clinical and Translational Gastroenterology, 12(11):e00427. Nature Publishing Group
van Vugt, A H M, Bijvelds, M J C, de Jonge, H R, Meijsen, K F, Restin, T, Bryant, M B, Ballauff, A, Koot, B, Müller, T, Houwen, R H J, Janecke, A R & Middendorp, S 2021, ' A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 12, no. 11, pp. e00427 . https://doi.org/10.14309/ctg.0000000000000427
Clinical and translational gastroenterology, 12(11). Nature Publishing Group
Clinical and Translational Gastroenterology
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 12(11). Nature Publishing Group

INTRODUCTION: Gain-of-function mutations in guanylyl cyclase C (GCC) result in persistent diarrhea with perinatal onset. We investigated a specific GCC inhibitor, SSP2518, for its potential to treat this disorder. METHODS: We investigated the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d3192ebcfb634acea304772d3b318e
https://pure.eur.nl/en/publications/476a3967-0cd2-4270-92cc-95c7bcb17260

[From annual check-up to annual appraisal: personalised diabetes care]

Autor: G E H M, Rutten, H A, van Vugt, I, de Weerdt, S W J, Lamberts, E J P, de Koning

Publikováno v: Nederlands tijdschrift voor geneeskunde. 160

Diabetes care is shifting from disease management to personalised care. Internationally, diabetes care providers are advised to integrate the patient's preferences, wishes and possibilities into diabetes care in order to improve its efficiency. The D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0a5e147ae998c430d329fdb9f333ddc
https://pubmed.ncbi.nlm.nih.gov/27405571

When too heavy is just fine: Creating trustworthy e-health advisors

Autor: Elly A. Konijn, H. C. van Vugt, Jolanda Veldhuis, Johan F. Hoorn

Publikováno v: International Journal of Human-computer Studies, 67(7), 571-583. Academic Press Inc.
Van Vught, H C, Konijn, E A, Hoorn, J F & Veldhuis, J 2009, ' When too heavy is just fine: Creating trustworthy e-health advisors ', International Journal of Human-computer Studies, vol. 67, no. 7, pp. 571-583 . https://doi.org/10.1016/j.ijhcs.2009.02.005

In using weight and diet advisors, people compare embodied agents with their actual selves and with the person they want to be: someone with an ideal weight; their ideal selves. In a laboratory and an online experiment, we scrutinized the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046c6481b40decf05dccaf4db3c3ba40
https://research.vu.nl/en/publications/33147024-509d-4777-b7c1-9531aefad1fe

Realism is not all! User engagement with task-related interface characters

Autor: Johan F. Hoorn, H. C. van Vugt, Elly A. Konijn, Anton Eliëns, I. Keur

Publikováno v: van Vugt, H C, Konijn, E A, Hoorn, J F, Eliëns, A P W & Keur, I 2007, ' Realism is not all! User engagement with task-related interface characters ', Interacting with Computers, vol. 19, no. 2, pp. 267-280 . https://doi.org/10.1016/j.intcom.2006.08.005
Interacting with Computers, 19(2), 267-280. Oxford University Press

Human-like characters in the interface may evoke social responses in users, and literature suggests that realism is the most important factor herein. However, the effects of interface characters on the user are not well understood. We developed an in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649d3288e2676f4a389eae054803a5a2
https://research.vu.nl/en/publications/7b5e9cd1-5905-4a52-8a02-1d403850b892

Neonatal Dexamethasone Treatment Increases Susceptibility to Experimental Autoimmune Disease in Adult Rats

Autor: F van Bel, J. M. Bakker, Annemieke Kavelaars, Cobi Jacoba Johanna Heijnen, Patrick Joseph Gerardus Hendrikus Kamphuis, Pieter M. Cobelens, H. H. Van Vugt

Publikováno v: The Journal of Immunology. 165:5932-5937

Major concern has emerged about the possible long term adverse effects of glucocorticoid treatment, which is frequently used for the prevention of chronic lung disease in preterm infants. Here we show that neonatal glucocorticoid treatment of rats in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87d960d736654aac06de09ec1462af8
https://doi.org/10.4049/jimmunol.165.10.5932