Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hēth R. Turnquist"'
Autor:
Kassandra J. Baron, Hēth R. Turnquist
Publikováno v:
Organogenesis, Vol 19, Iss 1 (2023)
ABSTRACTBased on successes in preclinical animal transplant models, adoptive cell therapy (ACT) with regulatory T cells (Tregs) is a promising modality to induce allograft tolerance or reduce the use of immunosuppressive drugs to prevent rejection. E
Externí odkaz:
https://doaj.org/article/89c8e652515c45e7bca87b5ca3b59f0d
IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease
Autor:
Gaelen K. Dwyer, Lisa R. Mathews, José A. Villegas, Anna Lucas, Anne Gonzalez de Peredo, Bruce R. Blazar, Jean-Philippe Girard, Amanda C. Poholek, Sanjiv A. Luther, Warren Shlomchik, Hēth R. Turnquist
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses. In allogeneic hematopoietic stem cell transplantation (alloHCT), recipient conditioning releases damage-associated molecular pa
Externí odkaz:
https://doaj.org/article/79d274cbbf384598a5e3943e8a19aee2
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/661785b178724830b5d60bd933b2615f
Autor:
Gaelen K. Dwyer, Hēth R. Turnquist
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Detrimental inflammatory responses after solid organ transplantation are initiated when immune cells sense pathogen-associated molecular patterns (PAMPs) and certain damage-associated molecular patterns (DAMPs) released or exposed during transplant-a
Externí odkaz:
https://doaj.org/article/58878939c5454e69959f9b2b726e38c5
Autor:
Johnny Bou Saba, Hēth R. Turnquist
Publikováno v:
Transplantation. 107:1069-1078
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f8342189c7d7776bb194d0bd413cb7f
https://doi.org/10.1097/tp.0000000000004447
https://doi.org/10.1097/tp.0000000000004447
Publikováno v:
Annual Review of Immunology. 40:15-43
Our understanding of the functions of the IL-1 superfamily cytokine and damage-associated molecular pattern IL-33 continues to evolve with our understanding of homeostasis and immunity. The early findings that IL-33 is a potent driver of type 2 immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19d3e9dfc1b86cc076348b064387822
https://doi.org/10.1146/annurev-immunol-101320-124243
https://doi.org/10.1146/annurev-immunol-101320-124243
Publikováno v:
Trends in immunology. 43(11)
Group 2 innate lymphoid cells (ILC2s) contribute to the maintenance of mammalian barrier tissue homeostasis. We review how ILC2s integrate epithelial signals and neurogenic components to preserve the tissue microenvironment and modulate inflammation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448d4a37ac92d2340417fb34443a3c48
https://pubmed.ncbi.nlm.nih.gov/36253275
https://pubmed.ncbi.nlm.nih.gov/36253275
Autor:
Benjamin M, Matta, Hēth R, Turnquist
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1371
Thymic-derived, regulatory T cells (Treg) represent a subset of CD4(+) T cells that are required for normal immune homeostasis and suppression of unwanted responses against self-antigens (Ags) that prevent autoimmunity. Their role as immune regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eec3bfc4019ca11c28cb701dd7c9d03e
https://pubmed.ncbi.nlm.nih.gov/26530793
https://pubmed.ncbi.nlm.nih.gov/26530793
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 380
Herein, we succinctly review mechanisms underlying self-tolerance and the roles of dendritic leukocytes (DCs) in T-cell tolerance to self and foreign antigens. We also consider the properties of naturally arising and other populations of regulatory T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d2110d59da9789f1965df0d4ea8faf3
https://pubmed.ncbi.nlm.nih.gov/17876084
https://pubmed.ncbi.nlm.nih.gov/17876084
Autor:
Virginia Camacho, Victoria R. Matkins, Sweta B. Patel, Jeremie M. Lever, Zhengqin Yang, Li Ying, Ashley E. Landuyt, Emma C. Dean, James F. George, Henry Yang, Paul Brent Ferrell, Craig L. Maynard, Casey T. Weaver, Heth R. Turnquist, Robert S. Welner
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory an
Externí odkaz:
https://doaj.org/article/1f60283a5d9849e4826f16038c6c5f98