Výsledky vyhledávání - "Hüseyin Sirma"

Akademický článek

Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report

Autor: Jürgen Kurt Rockstroh, Jan van Lunzen, Stefan Schmiedel, Hüseyin Sirma, Christian Noah, Knud Schewe, Oliver Schildgen

Publikováno v: Viruses, Vol 2, Iss 8, Pp 1564-1570 (2010)

A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatm

Externí odkaz: https://doaj.org/article/cdabd5aea8584a96b1d8f27b6b00c569

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Akademický článek

Matrix conditions and KLF2-dependent induction of heme oxygenase-1 modulate inhibition of HCV replication by fluvastatin.

Autor: Andrea Wuestenberg, Janine Kah, Katrin Singethan, Hüseyin Sirma, Amelie Dorothea Keller, Sergio René Perez Rosal, Jörg Schrader, Christine Loscher, Tassilo Volz, Ralf Bartenschlager, Volker Lohmann, Ulrike Protzer, Maura Dandri, Ansgar W Lohse, Gisa Tiegs, Gabriele Sass

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96533 (2014)

HMG-CoA-reductase-inhibitors (statins) have been shown to interfere with HCV replication in vitro. We investigated the mechanism, requirements and contribution of heme oxygenase-1(HO-1)-induction by statins to interference with HCV replication.HO-1-i

Externí odkaz: https://doaj.org/article/d9a789efe7fe4d4bba23098c50588636

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Supplementary Figure 2 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer

Autor: Ronald Simon, Hüseyin Sirma, Guido Sauter, Sarah Minner, Thorsten Schlomm, Markus Graefen, Thomas Steuber, Hartwig Huland, Frederik Bachmann, Martina Kluth, Malte Mader, Sawinee Masser, Antje Krohn, Sarah Fuchs, Lia Burkhardt

PDF file - 155K, Baseline CHD1 mRNA (a) and protein (b) expression levels in prostate cancer cell lines cells. Efficacy of ectopic overexpression of CHD1 in PC-3 cells on mRNA (c) and protein level (d) by Taqman PCR and immunoblot analysis, respectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1639382bd2320176d0a0264089050cb5
https://doi.org/10.1158/0008-5472.22399392.v1

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Supplementary Figure 4 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer

PDF file - 44K, Overexpression of RB1 and PTEN in PC-3 cells transfected with PSG5L-RB1 and PSG5L-PTEN as compared to the control vector PLNGY. Lysates were analysed for RB1 (a) and PTEN (b) by immunoblot analysis. Tubulin immunoblot served as loadin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7818e002783e80091db88ac20c16d94d
https://doi.org/10.1158/0008-5472.22399386

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Supplementary Figure 6 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer

PDF file - 163K, Homozygous CHD1 deletion in areas of prostatic intraepithelial neoplasia (PIN) and invasive cancer cells. Overwiew of a hematoxylin- and eosin stained tissue section containing areas of PIN (a, b) and invasive cancer (c). Correspondi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbaffa68e8b47d010031f36af4a8c4f
https://doi.org/10.1158/0008-5472.22399377

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Supplementary Figure 5 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer

PDF file - 636K, Impact of CHD1 on colony formation, soft agar growth and cell invasiveness. a) Effect of CHD1 overexpression on cell growth. DU-145 cells were transfected with expression vectors encoding CHD1, PLNGY (control) and the known tumor sup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7ec8626c496ad681360c5a046fe27a
https://doi.org/10.1158/0008-5472.22399383

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