Identification of preoptic sleep neurons using retrograde labelling and gene profiling

Autor: Chung, Shinjae, Weber, Franz, Zhong, Peng, Tan, Chan Lek, Nguyen, Thuc Nghi, Beier, Kevin T, Hörmann, Nikolai, Chang, Wei-Cheng, Zhang, Zhe, Do, Johnny Phong, Yao, Shenqin, Krashes, Michael J, Tasic, Bosiljka, Cetin, Ali, Zeng, Hongkui, Knight, Zachary A, Luo, Liqun, Dan, Yang

Publikováno v: Nature, vol 545, iss 7655

In humans and other mammalian species, lesions in the preoptic area of the hypothalamus cause profound sleep impairment, indicating a crucial role of the preoptic area in sleep generation. However, the underlying circuit mechanism remains poorly unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f0e423883433045493cfa1c6091c9a05
https://escholarship.org/uc/item/5ph3c89d

Identification of preoptic sleep neurons using retrograde labelling and gene profiling.

Autor: Chung S; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Weber F; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Zhong P; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Tan CL; Department of Physiology, University of California, San Francisco, San Francisco, California 94158, USA., Nguyen TN; Allen Institute for Brain Science, Seattle, Washington 98103, USA., Beier KT; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, USA., Hörmann N; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Chang WC; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Zhang Z; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Do JP; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Yao S; Allen Institute for Brain Science, Seattle, Washington 98103, USA., Krashes MJ; Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.; National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA., Tasic B; Allen Institute for Brain Science, Seattle, Washington 98103, USA., Cetin A; Allen Institute for Brain Science, Seattle, Washington 98103, USA., Zeng H; Allen Institute for Brain Science, Seattle, Washington 98103, USA., Knight ZA; Department of Physiology, University of California, San Francisco, San Francisco, California 94158, USA., Luo L; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, USA., Dan Y; Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA.

Publikováno v: Nature [Nature] 2017 May 25; Vol. 545 (7655), pp. 477-481. Date of Electronic Publication: 2017 May 17.