FGF2 gene's antisense protein, NUDT6, plays a depressogenic role by promoting inflammation and suppressing neurogenesis without altering FGF2 signalling.

Autor: Uzay B; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA.; Brain Institute, Vanderbilt University, Nashville, Tennessee, United States., Bahadır-Varol A; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey., Hökelekli FÖ; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.; Department of Psychiatry, University of Texas Southwestern, Dallas, TX, USA., Yılmaz M; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.; Department of Biology, Faculty of Science, Hacettepe University, Ankara, Turkey., Esen EC; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey., Başar K; Department of Psychiatry, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Ayhan Y; Department of Psychiatry, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Dalkara T; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey., Eren-Koçak E; Institute of Neurological Sciences and Psychiatry, Hacettepe University, Ankara, Turkey.; Department of Psychiatry, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Publikováno v: The Journal of physiology [J Physiol] 2024 Apr; Vol. 602 (7), pp. 1427-1442. Date of Electronic Publication: 2024 Mar 11.