Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Héloïse Ragelle"'
Autor:
Thomas L. Maurissen, Alena J. Spielmann, Gabriella Schellenberg, Marc Bickle, Jose Ricardo Vieira, Si Ying Lai, Georgios Pavlou, Sascha Fauser, Peter D. Westenskow, Roger D. Kamm, Héloïse Ragelle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Diabetic retinopathy (DR) is a microvascular disorder characterized by inner blood-retinal barrier (iBRB) breakdown and irreversible vision loss. While the symptoms of DR are known, disease mechanisms including basement membrane thickening,
Externí odkaz:
https://doaj.org/article/ec45dba5d88548cbb695e377fc41e056
Autor:
Héloïse Ragelle, Mark W. Tibbitt, Shang-Yun Wu, Michael A. Castillo, George Z. Cheng, Sidharta P. Gangadharan, Daniel G. Anderson, Michael J. Cima, Robert Langer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Integrating cell-laden hydrogels effectively into the 3D printing process is a challenge in the creation of tissue engineering scaffolds. Here, the authors describe an additive manufacturing technique to combine polymer and cell-containing networks w
Externí odkaz:
https://doaj.org/article/6821c75783f24309bc2cbbf92d921df0
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2475
Relevant human in vitro models of the retinal microvasculature can be used to study the role of disease mediators on retinal barrier dysfunction and assess the efficacy of early drug candidates. This chapter describes an organ-on-a-chip model of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa6e785092f688bd5b98433ca51c4cc4
https://pubmed.ncbi.nlm.nih.gov/35451763
https://pubmed.ncbi.nlm.nih.gov/35451763
Autor:
Leonard D. Goldstein, Filip Roudnicky, Bo Kyoung Kim, Claas A. Meyer, Lisa Sach-Peltason, Nikhil J. Pandya, Klaus Christensen, Christoph Patsch, Héloïse Ragelle, Oliv Eidam, Chad A. Cowan, Martin Graf, Pamela Strassburger, Zora Modrusan, Mark Burcin, Balazs Banfai, Verena Kueppers, Manuel Tzouros, Mirjana Lazendic, Sabine Uhles, Gregor Sturm, Peter D. Westenskow, Franco Revelant, Yanjun Lan, Jitao David Zhang, Sabine Gruener
Publikováno v:
Proc Natl Acad Sci U S A
The blood–retina barrier and blood–brain barrier (BRB/BBB) are selective and semipermeable and are critical for supporting and protecting central nervous system (CNS)-resident cells. Endothelial cells (ECs) within the BRB/BBB are tightly coupled,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2681eba3f4ec57913642788bbe14e23c
https://doi.org/10.1073/pnas.1911532117
https://doi.org/10.1073/pnas.1911532117
Autor:
Fangheng Zhou, Richard O. Hynes, Daniel G. Anderson, Robert Langer, Héloïse Ragelle, Benjamin L. Larson, Charles A. Whittaker, Amanda M. Del Rosario, Miralem Prijić, Alexandra Naba
Publikováno v:
Biomaterials
Prof. Hynes
Prof. Hynes
In the stem-cell niche, the extracellular matrix (ECM) serves as a structural support that additionally provides stem cells with signals that contribute to the regulation of stem-cell function, via reciprocal interactions between cells and components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048e2ed060733c2b40898890918a9dac
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e09ab42ec23ca5a8bf437a74a00d2b6
https://doi.org/10.1007/978-1-0716-2217-9_18
https://doi.org/10.1007/978-1-0716-2217-9_18
Autor:
Thomas L. Maurissen, Georgios Pavlou, Colette Bichsel, Roberto Villaseñor, Roger D. Kamm, Héloïse Ragelle
Publikováno v:
Journal of personalized medicine. 12(2)
Blood-neural barriers regulate nutrient supply to neuronal tissues and prevent neurotoxicity. In particular, the inner blood-retinal barrier (iBRB) and blood–brain barrier (BBB) share common origins in development, and similar morphology and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6009741add31590ec4b3dbe9fce0d39b
https://pubmed.ncbi.nlm.nih.gov/35207637
https://pubmed.ncbi.nlm.nih.gov/35207637
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606100
The fabrication of functional biomaterials for organ replacement and tissue repair remains a major goal of biomedical engineering. Advances in additive manufacturing (AM) technologies and computer-aided design (CAD) are advancing the tools available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eb7891c3999f7b8d53562f2ab3012f0
https://doi.org/10.1007/978-1-0716-0611-7_13
https://doi.org/10.1007/978-1-0716-0611-7_13
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2147
The fabrication of functional biomaterials for organ replacement and tissue repair remains a major goal of biomedical engineering. Advances in additive manufacturing (AM) technologies and computer-aided design (CAD) are advancing the tools available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3630a4dc969abd74c7bee5034e90169b
https://pubmed.ncbi.nlm.nih.gov/32840818
https://pubmed.ncbi.nlm.nih.gov/32840818
Autor:
Stefan Kustermann, Sascha Fauser, Sonia Khemais, Peter D. Westenskow, Héloïse Ragelle, Chris Louche, Cordula Keppler, Yohan Farouz, Lucien Cousin, Mark W. Tibbitt, Karen Dernick
Publikováno v:
Advanced Healthcare Materials. 9:2001531
Retinal cells within neurovascular units generate the blood-retinal barrier (BRB) to regulate the local retinal microenvironment and to limit access to inflammatory cells. Breakdown of the endothelial junctional complexes in the BRB negatively affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b475120a5f73fc4bfa21a3c7005eadd8
https://doi.org/10.1002/adhm.202001531
https://doi.org/10.1002/adhm.202001531